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Akademický článek

Fluoxetine protects against methamphetamine-induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats.

Autor: Yun Wang¹ ywang28@cmu.edu.cn, Yu-Han Gu¹, Ming Liu², Yang Bai¹, Huai-Liang Wang^1,3

Publikováno v: Molecular Medicine Reports. 2017, Vol. 15 Issue 2, p673-980. 8p.

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Fluoxetine protects against methamphetamine-induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats

Autor: Huai-Liang Wang, Yun Wang, Yu‑Han Gu, Ming Liu, Yang Bai

Publikováno v: Molecular Medicine Reports

Methamphetamine (MA) abuse is a major public health and safety concern throughout the world and a growing burden on healthcare costs. The purpose of the present study was to investigate the protective effect of fluoxetine against MA‑induced chronic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df18dc25c48c4e5ee1b2d026cf937c57
https://doi.org/10.3892/mmr.2016.6072

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Concurrence of autophagy with apoptosis in alveolar epithelial cells contributes to chronic pulmonary toxicity induced by methamphetamine

Autor: Ming Liu, Li-Ye Liang, Lin Shi, Mei-Jia Zhu, Yu-Han Gu, Bin Jiang, Xin Wang, Yun Wang

Publikováno v: Cell proliferation. 51(5)

Objectives Methamphetamine (MA) abuse evokes pulmonary toxicity. The aim of our study is to investigate if autophagy is induced by MA and if autophagy-initiated apoptosis in alveolar epithelial cells is involved in MA-induced chronic pulmonary toxici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61436d52d5e6f0acaedf1a1133333861
https://pubmed.ncbi.nlm.nih.gov/29956395

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TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity

Autor: Ming Liu, Li-Ye Liang, Yang Bai, Yu-Han Gu, Huai-Liang Wang, Yun Wang

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)

Methamphetamine (MA) leads to cardiac and pulmonary toxicity expressed as increases in inflammatory responses and oxidative stress. However, some interactions may exist between oxidative stress and endoplasmic reticulum stress (ERS). The current stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384245d476f86ec33a8443fab702dc3b
http://europepmc.org/articles/PMC5337881

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Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury

Autor: Ming Liu, Yun Wang, Yu-Han Gu, Yang Bai, Huai-Liang Wang

Publikováno v: Environmental toxicology and pharmacology. 49

Methamphetamine (MA) leads to multiple organs lesions and apoptosis. The aim of this study is to investigate if endoplasmic reticulum stress (ERS) - initiated apoptosis is involved in the chronic pulmonary injury induced by MA. In this study, rats we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ef5ead5d32239bc99a8f1b9eb07651
https://pubmed.ncbi.nlm.nih.gov/28081472

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Akademický článek

KLF13 Loss‐of‐Function Mutations Underlying Familial Dilated Cardiomyopathy

Autor: Yu‐Han Guo, Jun Wang, Xiao‐Juan Guo, Ri‐Feng Gao, Chen‐Xi Yang, Li Li, Yu‐Min Sun, Xing‐Biao Qiu, Ying‐Jia Xu, Yi‐Qing Yang

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 22 (2022)

Background Dilated cardiomyopathy (DCM), characterized by progressive left ventricular enlargement and systolic dysfunction, is the most common type of cardiomyopathy and a leading cause of heart failure and cardiac death. Accumulating evidence under

Externí odkaz: https://doaj.org/article/e02dc785a2bd4cfd9f79cf15812d19b1

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Akademický článek

Characterization of the cHS4 insulator in mouse embryonic stem cells

Autor: Xi‐bin Lu, Yu‐han Guo, Wei Huang

Publikováno v: FEBS Open Bio, Vol 10, Iss 4, Pp 644-656 (2020)

Synthetic biology circuits are often constructed with multiple gene expression units assembled in close proximity, and they can be used to perform complex functions in embryonic stem cells (ESCs). However, mutual interference between transcriptional

Externí odkaz: https://doaj.org/article/2749cd1436c0490e8c2b823fa9b135e2

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Akademický článek

Can Time-Lapse Incubation and Monitoring Be Beneficial to Assisted Reproduction Technology Outcomes? A Randomized Controlled Trial Using Day 3 Double Embryo Transfer

Autor: Yu-han Guo, Yan Liu, Lin Qi, Wen-yan Song, Hai-xia Jin

Publikováno v: Frontiers in Physiology, Vol 12 (2022)

Objective: To determine if the application of time-lapse incubation and monitoring can be beneficial to clinical outcomes in assisted reproductive technology.Methods: A total of 600 patients were equally randomized to three groups, namely, convention

Externí odkaz: https://doaj.org/article/058771b365394468a423b8e0c6dd0629

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Akademický článek

PRRX1 Loss‐of‐Function Mutations Underlying Familial Atrial Fibrillation

Autor: Xiao‐Juan Guo, Xing‐Biao Qiu, Jun Wang, Yu‐Han Guo, Chen‐Xi Yang, Li Li, Ri‐Feng Gao, Zun‐Ping Ke, Ruo‐Min Di, Yu‐Min Sun, Ying‐Jia Xu, Yi‐Qing Yang

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 23 (2021)

Background Atrial fibrillation (AF) is the most common form of clinical cardiac dysrhythmia responsible for thromboembolic cerebral stroke, congestive heart failure, and death. Aggregating evidence highlights the strong genetic basis of AF. Neverthel

Externí odkaz: https://doaj.org/article/43d6be9f7b214966928c21bdd4e668d3

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