Zobrazeno 1 - 10
of 484
pro vyhledávání: '"Yu-Chih Chen"'
Autor:
Mengli Zhou, Yushu Ma, Chun-Cheng Chiang, Edwin C. Rock, Samuel Charles Butler, Rajiv Anne, Svetlana Yatsenko, Yinan Gong, Yu-Chih Chen
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Considerable evidence suggests that breast cancer therapeutic resistance and relapse can be driven by polyploid giant cancer cells (PGCCs). The number of PGCCs increases with the stages of disease and therapeutic stress. Given the importance
Externí odkaz:
https://doaj.org/article/587f10ebc5df4bb19fe7f179e50945c8
Publikováno v:
International Journal of Health Policy and Management, Vol 12, Iss Issue 1, Pp 1-13 (2023)
Background Evidence of the impact of long-term care insurance (LTCI) on health and well-being has predominantly come from developed countries. China officially launched its city-level LTCI policy in 2016. Recent evidence in China has shown that havin
Externí odkaz:
https://doaj.org/article/776f71fae8c5471fb34339615494977f
Publikováno v:
Journal of the Formosan Medical Association, Vol 123, Iss 6, Pp 727-728 (2024)
Externí odkaz:
https://doaj.org/article/46210eaaa5cc4fd7b12045df79d2d0a9
Autor:
Sarah He, Muhammed Sillah, Aidan R. Cole, Apoorva Uboveja, Katherine M. Aird, Yu-Chih Chen, Yi-Nan Gong
Publikováno v:
Cells, Vol 13, Iss 12, p 1004 (2024)
Background: Identifying cells engaged in fundamental cellular processes, such as proliferation or living/death statuses, is pivotal across numerous research fields. However, prevailing methods relying on molecular biomarkers are constrained by high c
Externí odkaz:
https://doaj.org/article/361366edb0db42e89a5a3a855c51684d
Autor:
Parishmita Sarma, Carlo Marion C. Carino, Deeksha Seetharama, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Xue Rui, Yubo Cao, Kouki Kawakami, Poonam Kumari, Yu-Chih Chen, Kathryn E. Luker, Prem N. Yadav, Gary D. Luker, Stéphane A. Laporte, Xin Chen, Asuka Inoue, Arun K. Shukla
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chemokine receptors constitute an important subfamily of G protein-coupled receptors (GPCRs), and they are critically involved in a broad range of immune response mechanisms. Ligand promiscuity among these receptors makes them an interesting
Externí odkaz:
https://doaj.org/article/00c1bfe069ce44fd80ee66e1ab0d2340
Autor:
Mishal Rao, Yu-Kai Huang, Chia-Chun Liu, Chandler Meadows, Hui-Chun Cheng, Mengli Zhou, Yu-Chih Chen, Xin Xia, Jeffrey L. Goldberg, Andrew M. Williams, Takaaki Kuwajima, Kun-Che Chang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract As part of the central nervous system (CNS), retinal ganglion cells (RGCs) and their axons are the only neurons in the retina that transmit visual signals from the eye to the brain via the optic nerve (ON). Unfortunately, they do not regener
Externí odkaz:
https://doaj.org/article/65c1f36d05de4c6aa38bd2db14f7b436
Autor:
Giuseppina Augimeri, Maria E. Gonzalez, Alessandro Paolì, Ahmad Eido, Yehyun Choi, Boris Burman, Sabra Djomehri, Santhosh Kumar Karthikeyan, Sooryanarayana Varambally, Johanna M. Buschhaus, Yu-Chih Chen, Loredana Mauro, Daniela Bonofiglio, Alexey I. Nesvizhskii, Gary D. Luker, Sebastiano Andò, Euisik Yoon, Celina G. Kleer
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Patients with triple-negative breast cancer remain at risk for metastatic disease despite treatment. The acquisition of chemoresistance is a major cause of tumor relapse and death, but the mechanisms are far from understood. We have demonstrated that
Externí odkaz:
https://doaj.org/article/0fdb611aabcf4f8398eea1d60e3165be
Autor:
Faith O. Osinaga, Yu-Chih Chen, Madan K. Kharel, Yan Waguespack, Sichu Li, Shaochung Victor Hsia
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1104 (2023)
We reported that gamma-hydroxybutyrate (GHB) is released upon Herpes Simplex Virus Type-1 (HSV-1) acute infection. However, the cellular biochemical processes involved in the production of GHB in infected cells are unclear. This study aims to shed li
Externí odkaz:
https://doaj.org/article/88f2124cc116411585a51b91479f7330
Autor:
Maria E. Gonzalez, Giuseppina Daniela Naimo, Talha Anwar, Alessandro Paolì, Shilpa R. Tekula, Suny Kim, Natasha Medhora, Shoshana A. Leflein, Jacob Itkin, Raymond Trievel, Kelley M. Kidwell, Yu-Chih Chen, Loredana Mauro, Euisik Yoon, Sebastiano Andò, Celina G. Kleer
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104827- (2022)
Summary: Triple-negative breast cancers (TNBCs) are frequently poorly differentiated with high propensity for metastasis. Enhancer of zeste homolog 2 (EZH2) is the lysine methyltransferase of polycomb repressive complex 2 that mediates transcriptiona
Externí odkaz:
https://doaj.org/article/5c9cd17d3caa45c1b3036fa63d85ad3f
Autor:
Ajai J. Pulianmackal, Dan Sun, Kenji Yumoto, Zhengda Li, Yu-Chih Chen, Meha V. Patel, Yu Wang, Euisik Yoon, Alexander Pearson, Qiong Yang, Russell Taichman, Frank C. Cackowski, Laura A. Buttitta
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The proliferation-quiescence decision is a dynamic process that remains incompletely understood. Live-cell imaging with fluorescent cell cycle sensors now allows us to visualize the dynamics of cell cycle transitions and has revealed that proliferati
Externí odkaz:
https://doaj.org/article/16500dfcccc5484ebdef456c2397da83