Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Yu-Chiao Chiu"'
Autor:
Cheng-Han Wu, Yu-Chiao Chiu
Publikováno v:
Journal of Cancer Research and Practice, Vol 11, Iss 2, Pp 62-66 (2024)
Objective: Immune checkpoint inhibitors (ICIs) have become an important treatment option for cancer. However, the predictive power of current biomarkers is limited for treatment response, especially in triple-negative breast cancer (TNBC). Investigat
Externí odkaz:
https://doaj.org/article/dda2f5b44a244183baf64d723f9ee354
Autor:
Carla Zeballos Torrez, Acarizia Easley, Hakim Bouamar, Guixi Zheng, Xiang Gu, Junhua Yang, Yu-Chiao Chiu, Yidong Chen, Glenn A. Halff, Francisco G. Cigarroa, Lu-Zhe Sun
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Six Transmembrane Epithelial Antigen of Prostate 2 (STEAP2) belongs to a family of metalloreductases, which indirectly aid in uptake of iron and copper ions. Its role in hepatocellular carcinoma (HCC) remains to be characterized. Here, we re
Externí odkaz:
https://doaj.org/article/06f30e39d0924192bb9c64cb274a9c44
Autor:
Anwaar Saeed, Robin Park, Harsh Pathak, Ayah Nedal Al-Bzour, Junqiang Dai, Milind Phadnis, Raed Al-Rajabi, Anup Kasi, Joaquina Baranda, Weijing Sun, Stephen Williamson, Yu-Chiao Chiu, Hatice Ulku Osmanbeyoglu, Rashna Madan, Hassan Abushukair, Kelly Mulvaney, Andrew K. Godwin, Azhar Saeed
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract CAMILLA is a basket trial (NCT03539822) evaluating cabozantinib plus the ICI durvalumab in chemorefractory gastrointestinal cancer. Herein, are the phase II colorectal cohort results. 29 patients were evaluable. 100% had confirmed pMMR/MSS t
Externí odkaz:
https://doaj.org/article/ef214cc1e88d4bb382653082f8b6a181
Autor:
Jian Zou, Osama Shah, Yu-Chiao Chiu, Tianzhou Ma, Jennifer M Atkinson, Steffi Oesterreich, Adrian V Lee, George C Tseng
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011754 (2024)
Cancer models are instrumental as a substitute for human studies and to expedite basic, translational, and clinical cancer research. For a given cancer type, a wide selection of models, such as cell lines, patient-derived xenografts, organoids and ge
Externí odkaz:
https://doaj.org/article/d6056c710d1441368e8499b836e820b4
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background The state-of-the-art deep learning based cancer type prediction can only predict cancer types whose samples are available during the training where the sample size is commonly large. In this paper, we consider how to utilize the e
Externí odkaz:
https://doaj.org/article/6e34493e23d54b46a66fb1e4a7ddf5f5
Publikováno v:
BMC Medical Genomics, Vol 13, Iss S5, Pp 1-13 (2020)
Abstract Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Through a predictive model, important cancer marker genes can be inferred. Several studies have attempted to build machine learning models for this task
Externí odkaz:
https://doaj.org/article/3b580f3653204baca4bc1e8d0340ec79
Autor:
Li-Ju Wang, Catherine W. Zhang, Sophia C. Su, Hung-I H. Chen, Yu-Chiao Chiu, Zhao Lai, Hakim Bouamar, Amelie G. Ramirez, Francisco G. Cigarroa, Lu-Zhe Sun, Yidong Chen
Publikováno v:
BMC Genomics, Vol 20, Iss S12, Pp 1-14 (2019)
Abstract Background Europeans and American Indians were major genetic ancestry of Hispanics in the U.S. These ancestral groups have markedly different incidence rates and outcomes in many types of cancers. Therefore, the genetic admixture may cause b
Externí odkaz:
https://doaj.org/article/6f841f21e0174d6690f11bfbde34b91a
Autor:
Cheng-Hong Tsai, Chi-Yuan Yao, Feng-Min Tien, Jih-Luh Tang, Yuan-Yeh Kuo, Yu-Chiao Chiu, Chien-Chin Lin, Mei-Hsuan Tseng, Yen-Ling Peng, Ming-Chih Liu, Chia-Wen Liu, Ming Yao, Liang-In Lin, Wen-Chien Chou, Chien-Yu Chen, Hsin-An Hou, Hwei-Fang Tien
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 240-250 (2019)
Background: Expression of long non-coding RNAs (lncRNAs) has recently been recognized as a potential prognostic marker in acute myeloid leukemia (AML). However, it remains unclear whether incorporation of the lncRNAs expression in the 2017 European L
Externí odkaz:
https://doaj.org/article/9408d3a4d7ab488fb4e6d2b8f6f08a36
Publikováno v:
BMC Genomics, Vol 20, Iss S1, Pp 17-29 (2019)
Abstract Background Cell lines form the cornerstone of cell-based experimentation studies into understanding the underlying mechanisms of normal and disease biology including cancer. However, it is commonly acknowledged that contamination of cell lin
Externí odkaz:
https://doaj.org/article/035fd043f5af413f8fbeefbcecd26068
Autor:
Yu-Chiao Chiu, Hung-I Harry Chen, Tinghe Zhang, Songyao Zhang, Aparna Gorthi, Li-Ju Wang, Yufei Huang, Yidong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S1, Pp 143-155 (2019)
Abstract Background The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent study screened for the response of a thousand human
Externí odkaz:
https://doaj.org/article/431965f3a55c42008775e01409ca85e1