Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yu Zoe Zhang"'
Autor:
Jared S. Bee, Yu (Zoe) Zhang, Megan Kuhn Phillippi, Sheyla Finkner, Tesfu Mezghebe, Keith Webber, Win Den Cheung, Tristan Marshall
Publikováno v:
Journal of pharmaceutical sciences. 111(5)
There are an increasing number of clinical studies evaluating different adeno-associated virus (AAV) serotypes as vectors for gene therapy. Long-term frozen storage can maximize the stability of AAV. Freeze-thaw (F/T) cycles and exposures to room tem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea2d47e2decad6afd915def76befa9c
https://pubmed.ncbi.nlm.nih.gov/34999092
https://pubmed.ncbi.nlm.nih.gov/34999092
Publikováno v:
International journal of pharmaceutics. 606
Adeno-associated viruses (AAV) are among the most actively investigated vectors for gene therapy. Supply of early clinical studies with frozen drug product (DP) can accelerate timelines and minimize degradation risks. In the long-term, logistical cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c087dd881b8ca9b258583d6755ac2fd
https://pubmed.ncbi.nlm.nih.gov/34298099
https://pubmed.ncbi.nlm.nih.gov/34298099
Autor:
Yu Zoe Zhang, Jared S. Bee, Megan Kuhn Phillippi, Kristin B. O'berry, Roberto A DePaz, Akanksha Kaushal, Tristan Marshall
Publikováno v:
Journal of pharmaceutical sciences. 110(9)
Adeno-associated virus (AAV) vectors for gene therapy have potential to provide a durable treatment response for a number of diseases with unmet need. DNA is released from AAV capsids at high temperatures. Less is known about DNA release that may occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e24c8407bf83abf24319290077bc60
https://pubmed.ncbi.nlm.nih.gov/34107283
https://pubmed.ncbi.nlm.nih.gov/34107283