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of 282
pro vyhledávání: '"Yu Zhaoxia"'
It is crucial to assess the predictive performance of a model in order to establish its practicality and relevance in real-world scenarios, particularly for high-dimensional data analysis. Among data splitting or resampling methods, cross-validation
Externí odkaz:
http://arxiv.org/abs/2408.03138
Molecular and genomic technological advancements have greatly enhanced our understanding of biological processes by allowing us to quantify key biological variables such as gene expression, protein levels, and microbiome compositions. These breakthro
Externí odkaz:
http://arxiv.org/abs/2406.06767
We propose a statistical framework to investigate whether a given subpopulation lies between two other subpopulations in a multivariate feature space. This methodology is motivated by a biological question from a collaborator: Is a newly discovered c
Externí odkaz:
http://arxiv.org/abs/2103.09718
With the increasing popularity of calcium imaging data in neuroscience research, methods for analyzing calcium trace data are critical to address various questions. The observed calcium traces are either analyzed directly or deconvolved to spike trai
Externí odkaz:
http://arxiv.org/abs/2103.02163
We propose a ridge-penalized adaptive Mantel test (AdaMant) for evaluating the association of two high-dimensional sets of features. By introducing a ridge penalty, AdaMant tests the association across many metrics simultaneously. We demonstrate how
Externí odkaz:
http://arxiv.org/abs/2103.02156
Optical imaging of genetically encoded calcium indicators is a powerful tool to record the activity of a large number of neurons simultaneously over a long period of time from freely behaving animals. However, determining the exact time at which a ne
Externí odkaz:
http://arxiv.org/abs/2103.03818
Recent advancements in miniaturized fluorescence microscopy have made it possible to investigate neuronal responses to external stimuli in awake behaving animals through the analysis of intra-cellular calcium signals. An on-going challenge is deconvo
Externí odkaz:
http://arxiv.org/abs/2102.09403
We propose a two-stage approach Spec PC-CP to identify change points in multivariate time series. In the first stage, we obtain a low-dimensional summary of the high-dimensional time series by Spectral Principal Component Analysis (Spec-PCA). In the
Externí odkaz:
http://arxiv.org/abs/2101.04334
Akademický článek
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Autor:
Potkin Steven G, Guffanti Guia, Subramanian Aravind, Macciardi Fabio, Weng Lingjie, Yu Zhaoxia, Xie Xiaohui
Publikováno v:
BMC Bioinformatics, Vol 12, Iss 1, p 99 (2011)
Abstract Background Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variations, mostly in the form of single nucleotide polymorphisms (SNPs
Externí odkaz:
https://doaj.org/article/28531c4ed74748baada7881e12f422ce