Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yu Ting Ong"'
Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2
Autor:
Rui Li, Jingchen Shao, Young-June Jin, Haruya Kawase, Yu Ting Ong, Kerstin Troidl, Qi Quan, Lei Wang, Remy Bonnavion, Astrid Wietelmann, Francoise Helmbacher, Michael Potente, Johannes Graumann, Nina Wettschureck, Stefan Offermanns
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The authors report that endothelial protocadherin FAT1 inhibits endothelial proliferation and angiogenesis by promoting degradation of the transcriptional cofactors YAP and TAZ by direct interaction with the E3 ubiquitin ligase Mind Bomb-2 (MIB2).
Externí odkaz:
https://doaj.org/article/ae8cf225971e49d0b6bc0f0653d4b7c5
Autor:
Lei Wang, ShengPeng Wang, Yue Shi, Rui Li, Stefan Günther, Yu Ting Ong, Michael Potente, Zuyi Yuan, Enqi Liu, Stefan Offermanns
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The expansion of the white adipose tissue during obesity is accompanied by increased cellular stress, but factors that protect adipocytes from cell death are not well known. Here the authors report that the transcriptional co-activators YAP and TAZ a
Externí odkaz:
https://doaj.org/article/7a8432b5796c4c8c88ffb842b61592ee
Autor:
Ryuichi Fukuda, Alla Aharonov, Yu Ting Ong, Oliver A Stone, Mohamed El-Brolosy, Hans-Martin Maischein, Michael Potente, Eldad Tzahor, Didier YR Stainier
Publikováno v:
eLife, Vol 8 (2019)
During cardiac development, cardiomyocytes form complex inner wall structures called trabeculae. Despite significant investigation into this process, the potential role of metabolism has not been addressed. Using single cell resolution imaging in zeb
Externí odkaz:
https://doaj.org/article/b39dd6c217ae4752949b566bf0a577b0
Autor:
Filipa Neto, Alexandra Klaus-Bergmann, Yu Ting Ong, Silvanus Alt, Anne-Clémence Vion, Anna Szymborska, Joana R Carvalho, Irene Hollfinger, Eireen Bartels-Klein, Claudio A Franco, Michael Potente, Holger Gerhardt
Publikováno v:
eLife, Vol 7 (2018)
Formation of blood vessel networks by sprouting angiogenesis is critical for tissue growth, homeostasis and regeneration. How endothelial cells arise in adequate numbers and arrange suitably to shape functional vascular networks is poorly understood.
Externí odkaz:
https://doaj.org/article/b2e688ced8914f49a847a12fffdbab93
Autor:
Yu Ting Ong, Jorge Andrade, Max Armbruster, Chenyue Shi, Marco Castro, Ana S. H. Costa, Toshiya Sugino, Guy Eelen, Barbara Zimmermann, Kerstin Wilhelm, Joseph Lim, Shuichi Watanabe, Stefan Guenther, Andre Schneider, Francesca Zanconato, Manuel Kaulich, Duojia Pan, Thomas Braun, Holger Gerhardt, Alejo Efeyan, Peter Carmeliet, Stefano Piccolo, Ana Rita Grosso, Michael Potente
Publikováno v:
Nature Metabolism
Funding Information: The research in the M.P. laboratory was supported by the Max Planck Society, the European Research Council (ERC) Consolidator Grant EMERGE (no. 773047), the Deutsche Forschungsgemeinschaft (DFG, Project-ID 75732319 – SFB 834),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949e298d1cb95c83b830f240881e3703
https://doi.org/10.1038/s42255-022-00584-y
https://doi.org/10.1038/s42255-022-00584-y
Autor:
Marco Castro, Kerstin Wilhelm, Yoshiaki Kubota, Gou Young Koh, Christian Frezza, Jorge Andrade, Thomas Braun, Jeongwoon Choi, Jaeryung Kim, Anuradha Doddaballapur, Barbara Zimmermann, Stefan Guenther, Yu Ting Ong, Toshiya Sugino, Manuel Kaulich, Ana Rita Grosso, Ana S. H. Costa, Chenyue Shi, Michael Potente
Publikováno v:
Nature Cell Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© 2021 Springer Nature Limited. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52e2159f7d02b8ee96472905ba43b33
Autor:
Deborah Yu Ting Ong
Publikováno v:
Scaling up ICT-based Innovations in Schools ISBN: 9789811644689
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab32a95cc3b99b2c28202d96da70ca1
https://doi.org/10.1007/978-981-16-4469-6_6
https://doi.org/10.1007/978-981-16-4469-6_6
Autor:
Michael Potente, Yu Ting Ong, Lei Wang, Yue Shi, Zuyi Yuan, Shengpeng Wang, Stefan Günther, Enqi Liu, Stefan Offermanns, Rui Li
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The expansion of the white adipose tissue (WAT) in obesity goes along with increased mechanical, metabolic and inflammatory stress. How adipocytes resist this stress is still poorly understood. Both in human and mouse adipocytes, the transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386e830f19da92d6205057edb1482bc3
Autor:
Alla Aharonov, Oliver A. Stone, Didier Y.R. Stainier, Yu Ting Ong, Ryuichi Fukuda, Michael Potente, Eldad Tzahor, Hans-Martin Maischein, Mohamed A. El-Brolosy
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
During cardiac development, cardiomyocytes form complex inner wall structures called trabeculae. Despite significant investigation into this process, the potential role of metabolism has not been addressed. Using single cell resolution imaging in zeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7a333380a4257b5e657ad424b3c5f9
https://elifesciences.org/articles/50161
https://elifesciences.org/articles/50161
Autor:
Oliver A. Stone, Mohamed A. El-Brolosy, Hans-Martin Maischein, Didier Y.R. Stainier, Alla Aharonov, Eldad Tzahor, Michael Potente, Yu Ting Ong, Ryuichi Fukuda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11d5786d17680acc871d32daaa498b1b
https://doi.org/10.7554/elife.50161.sa2
https://doi.org/10.7554/elife.50161.sa2