The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

Autor: Ines Hahn, André Voelzmann, Yu-Ting Liew, Beatriz Costa-Gomes, Andreas Prokop

Publikováno v: Neural Development, Vol 14, Iss 1, Pp 1-28 (2019)

Abstract Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime. This makes them

Externí odkaz: https://doaj.org/article/cc49e45a31e041a78115bd47689071b9

The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology

Autor: Andreas Prokop, André Voelzmann, Yu-Ting Liew, Ines Hahn, Beatriz Costa-Gomes

Publikováno v: Neural Development, Vol 14, Iss 1, Pp 1-28 (2019)
Neural Development
Hahn, I, Voelzmann, A, Liew, Y T, Costa Gomes, B & Prokop, A 2019, ' The model of local axon homeostasis-explaining the role and regulation of microtubule bundles in axon maintenance and pathology ', Neural Development, vol. 14, no. 11, 10.1186/s13064-019-0134-0 . https://doi.org/10.1186/s13064-019-0134-0

Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime. This makes them key lesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3888fa799dc945b2f630712a614cef51
http://link.springer.com/article/10.1186/s13064-019-0134-0

DrosophilaShort stop as a paradigm for the role and regulation of spectraplakins

Autor: Natalia Sanchez-Soriano, Andreas Prokop, Cristina Melero, Yu Ting Liew, Ines Hahn, André Voelzmann, Yue Qu

Publikováno v: SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Voelzmann, A, Liew, Y T, Qu, Y, Hahn, I, Melero, C, Sanchez-Soriano, N & Prokop, A 2017, ' Drosophila Short stop as a paradigm for the role and regulation of spectraplakins ', Seminars in Cell and Developmental Biology, vol. 69, YSCDB2225, pp. 40-57 . https://doi.org/10.1016/j.semcdb.2017.05.019

Spectraplakins are evolutionarily well conserved cytoskeletal linker molecules that are true members of three protein families: plakins, spectrins and Gas2-like proteins. Spectraplakin genes encode at least 7 characteristic functional domains which a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d36fe5acdbb62dfc3ef36375e62b403
https://doi.org/10.1101/122010