Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Yu Sone"'
1
Generic approach for the discovery of drug metabolites in horses based on data-dependent acquisition by liquid chromatography high-resolution mass spectrometry and its applications to pharmacokinetic study of daprodustat
Autor: Hideaki Ishii, Mariko Shibuya, Kanichi Kusano, Yu Sone, Takahiro Kamiya, Ai Wakuno, Hideki Ito, Kenji Miyata, Fumio Sato, Taisuke Kuroda, Masayuki Yamada, Gary Ngai-Wa Leung
Publikováno v: Analytical and Bioanalytical Chemistry. 414:8125-8142
In drug metabolism studies in horses, non-targeted analysis by means of liquid chromatography coupled with high-resolution mass spectrometry with data-dependent acquisition (DDA) has recently become increasingly popular for rapid identification of po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708b1df2fece21db1b1248f4c59e55a5
https://doi.org/10.1007/s00216-022-04347-2
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2
Comprehensive metabolic study of IOX4 in equine urine and plasma using liquid chromatography/electrospray ionization Q Exactive high‐resolution mass spectrometer for the purpose of doping control
Autor: Jenny K.Y. Wong, Yat-Ming So, Kanichi Kusano, Yu Sone, Masayuki Yamada, Takahiro Kamiya, Emmie N.M. Ho, Hideaki Ishii, Ai Wakuno, Hideki Ito, Mariko Shibuya, Gary Ngai-Wa Leung, Kenji Miyata
Publikováno v: Drug Testing and Analysis. 14:233-251
IOX4 is a hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor, which was developed for the treatment of anemia by exerting hematopoietic effects. The administration of HIF-PHD inhibitors such as IOX4 to horses is strictly prohibited by th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30447b32ff75c15c6dafbe05b516909f
https://doi.org/10.1002/dta.3172
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3
Pharmacokinetic Study of Vadadustat and High-Resolution Mass Spectrometric Characterization of its Novel Metabolites in Equines for the Purpose of Doping Control
Autor: Hideaki Ishii, Mariko Shibuya, Kanichi Kusano, Yu Sone, Takahiro Kamiya, Ai Wakuno, Hideki Ito, Kenji Miyata, Fumio Sato, Taisuke Kuroda, Masayuki Yamada, Gary Ngai-Wa Leung
Publikováno v: Current drug metabolism. 23(10)
Background: Vadadustat, a hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitor, is a substance which carries a lifetime ban in both horse racing and equestrian competition. A comprehensive metabolic study of vadadustat in horses has not be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230f7f06f6ebb54032da7bb791996d7e
https://pubmed.ncbi.nlm.nih.gov/36017833
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4
Akademický článek
Generic approach for the discovery of drug metabolites in horses based on data-dependent acquisition by liquid chromatography high-resolution mass spectrometry and its applications to pharmacokinetic study of daprodustat.
Autor: Ishii, Hideaki1,2 (AUTHOR) h-ishii@lrc.or.jp, Shibuya, Mariko1 (AUTHOR), Kusano, Kanichi3 (AUTHOR), Sone, Yu3 (AUTHOR), Kamiya, Takahiro4 (AUTHOR), Wakuno, Ai4 (AUTHOR), Ito, Hideki4 (AUTHOR), Miyata, Kenji5 (AUTHOR), Sato, Fumio6 (AUTHOR), Kuroda, Taisuke6 (AUTHOR), Yamada, Masayuki1 (AUTHOR), Leung, Gary Ngai-Wa1 (AUTHOR)
Publikováno v: Analytical & Bioanalytical Chemistry. Nov2022, Vol. 414 Issue 28, p8125-8142. 18p.
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