Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yu Sherry Jiang"'
Autor:
Sanchita Bhadra, Yu Sherry Jiang, Mia R Kumar, Reed F Johnson, Lisa E Hensley, Andrew D Ellington
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123126 (2015)
The Middle East respiratory syndrome coronavirus (MERS-CoV), an emerging human coronavirus, causes severe acute respiratory illness with a 35% mortality rate. In light of the recent surge in reported infections we have developed asymmetric five-prime
Externí odkaz:
https://doaj.org/article/23515e760c174d4887d51de0e16481b5
Publikováno v:
Analytical Chemistry. 88:2250-2257
During the past decade, aptasensors have largely been designed on the basis of the notion that ligand-modulated equilibration between aptamer conformations could be exploited for sensing. One implementation of this strategy has been to denature the a
Autor:
Yuefeng Wu, Yu Sherry Jiang, John N. Milligan, Bingling Li, Sanchita Bhadra, Andrew D. Ellington
Publikováno v:
Analytical Chemistry. 87:3314-3320
Loop-mediated isothermal amplification (LAMP) of DNA is a powerful isothermal nucleic acid amplification method that can generate upward of 10(9) copies from less than 100 copies of template DNA within an hour. Unfortunately, although the amplificati
Autor:
Sanchita Bhadra, Yu Sherry Jiang, Andrew D. Ellington, Jessica A. Popoola, Barrett R. Morrow, Sheng Cai, Timothy E. Riedel
Publikováno v:
Water Research
Human fecal contamination of water is a public health risk. However, inadequate testing solutions frustrate timely, actionable monitoring. Bacterial culture-based methods are simple but typically cannot distinguish fecal host source. PCR assays can i
Publikováno v:
ChemBioChem
It is inherently difficult to quantitate nucleic acid analytes with most isothermal amplification assays. We have now developed loop-mediated isothermal amplification (LAMP) reactions in which competition between defined numbers of 'false' and 'true'
Publikováno v:
Angewandte Chemie. 126:1876-1879
Catalytic hairpin assembly (CHA) has previously proven useful as a transduction and amplification method for nucleic acid detection. However, the two hairpin substrates in a CHA circuit can potentially react non-specifically even in the absence of a
Publikováno v:
Journal of the American Chemical Society. 135:7430-7433
Catalytic hairpin assembly (CHA) is an enzyme-free amplification method that has previously proven useful in amplifying and transducing signals at the terminus of nucleic acid amplification reactions. Here, for the first time, we engineered CHA to be
Autor:
Sanchita Bhadra, Zhentong Zhu, Yan Du, Andrew D. Ellington, Bingling Li, Yu Sherry Jiang, Yidan Tang
Publikováno v:
Scientific Reports
Catalytic hairpin assembly (CHA) is one of the most promising nucleic acid amplification circuits based on toehold-mediated strand exchange reactions. But its performance is usually ruined by fluctuated environmental temperatures or unexpected self-s
Publikováno v:
Molecules, Vol 17, Iss 11, Pp 13211-13220 (2012)
Molecules
Molecules; Volume 17; Issue 11; Pages: 13211-13220
Molecules
Molecules; Volume 17; Issue 11; Pages: 13211-13220
DNA circuits have proven to be useful amplifiers for diagnostic applications, in part because of their modularity and programmability. In order to determine whether different circuits could be modularly stacked, we used a catalytic hairpin assembly (
Publikováno v:
Analytical Letters. 45:1919-1927
A novel fluorescence assay, based on the signal amplification through cycling reactions of aptameric recognition and nucleic acid exo-cleaving, was established for the sensitive detection of cocaine. In this assay, a new single fluorophore-labeled DN