Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Yu Seok Youn"'
Autor:
Nguyen Thi Nguyen, Xuan Thien Le, Woo Tak Lee, Yong Taik Lim, Kyung Taek Oh, Eun Seong Lee, Han-Gon Choi, Yu Seok Youn
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 345-365 (2024)
Recently, nanovaccine-based immunotherapy has been robustly investigated due to its potential in governing the immune response and generating long-term protective immunity. However, the presentation of a tumor peptide-major histocompatibility complex
Externí odkaz:
https://doaj.org/article/13df5ecfcd1c429098a841239237a4ef
Autor:
Jung Suk Kim, Seunghyun Cheon, Mi Ran Woo, Sanghyun Woo, Jee-Eun Chung, Yu Seok Youn, Kyung Taek Oh, Soo-Jeong Lim, Sae Kwang Ku, Bao Loc Nguyen, Jong Oh Kim, Sung Giu Jin, Han-Gon Choi
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 5, Pp 100953- (2024)
While spray-drying has been widely utilized to improve the bioavailability of poorly water-soluble drugs, the outcomes often exhibit suboptimal particle size distribution and large particle sizes, limiting their effectiveness. In this study, we intro
Externí odkaz:
https://doaj.org/article/844b702e265c4c8c97a71e59fa692049
Autor:
Woo Tak Lee, Hyunjun Lee, Juho Kim, Yujin Jung, Eojin Choi, Ji Hoon Jeong, Jee-Heon Jeong, Jung Heon Lee, Yu Seok Youn
Publikováno v:
Bioactive Materials, Vol 33, Iss , Pp 262-278 (2024)
Idiopathic pulmonary fibrosis (IPF) is a chronic inflammatory and fibrotic response-driven lung disease that is difficult to cure because it manifests excessive profibrotic cytokines (e.g., TGF-β), activated myofibroblasts, and accumulated extracell
Externí odkaz:
https://doaj.org/article/88288d20049c4f0b9d390aaba1442c2d
Autor:
Hanju Kim, Johyun Yoon, Hwang Kyung Kim, Woo Tak Lee, Nguyen Thi Nguyen, Xuan Thien Le, Eun-Hee Lee, Eun Seong Lee, Kyung Taek Oh, Han-Gon Choi, Yu Seok Youn
Publikováno v:
Bioactive Materials, Vol 22, Iss , Pp 112-126 (2023)
Inspired by erythrocytes that contain oxygen-carrying hemoglobin (Hb) and that exhibit photo-driven activity, we introduce homogenous-sized erythrocyte-like Hb microgel (μGel) systems (5–6 μm) that can (i) emit heat, (ii) supply oxygen, and (iii)
Externí odkaz:
https://doaj.org/article/12a32e5f60f2423cab17eda265aedd11
Autor:
Woo Tak Lee, Junyeong Lee, Hanju Kim, Nguyen Thi Nguyen, Eun Seong Lee, Kyung Taek Oh, Han-Gon Choi, Yu Seok Youn
Publikováno v:
Materials Today Bio, Vol 12, Iss , Pp 100164- (2021)
Depletion of tumor extracellular matrix (ECM) is viewed as a promising approach to enhance the antitumor efficacy of chemotherapeutic-loaded nanoparticles. Hyaluronidase (HAase) destroys hyaluronic acid-based tumor ECM, but it is active solely at aci
Externí odkaz:
https://doaj.org/article/04c933e81e9a4e7397ccedd69b3ec6ee
Autor:
Marina Santiago Franco, Yu Seok Youn
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 851 (2022)
Since clinical approval of the first liposomal formulation encapsulating a chemotherapeutic agent, nanoscale delivery systems have been a rapidly developing science [...]
Externí odkaz:
https://doaj.org/article/75ac559fb6354a0a83eb4ec9612b5f78
Autor:
Woo Tak Lee, Johyun Yoon, Sung Soo Kim, Hanju Kim, Nguyen Thi Nguyen, Xuan Thien Le, Eun Seong Lee, Kyung Taek Oh, Han-Gon Choi, Yu Seok Youn
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 148 (2022)
Combined therapy using photothermal and photodynamic treatments together with chemotherapeutic agents is considered one of the most synergistic treatment protocols to ablate hypoxic tumors. Herein, we sought to fabricate an in situ-injectable PEG hyd
Externí odkaz:
https://doaj.org/article/6e80b120c0504121bca32a4928fcbb87
Autor:
Taehoon Sim, Jae Eun Kim, Ngoc Ha Hoang, Jin Kook Kang, Chaemin Lim, Dong Shik Kim, Eun Seong Lee, Yu Seok Youn, Han-Gon Choi, Hyo-Kyung Han, Kwon-Yeon Weon, Kyung Taek Oh
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1362-1371 (2018)
Docetaxel (DTX)-loaded polymeric micelles (DTBM) were formulated using the triblock copolymer, poly(ethylene glycol)–polylactide–poly(ethylene glycol) (PEG–PLA–PEG), to comprehensively study their pharmaceutical application as anticancer nano
Externí odkaz:
https://doaj.org/article/63bce60ed67e42f88ebfcdfaab1d8902
Autor:
Kyeong Soo Kim, Eun Su Yang, Dong Shik Kim, Dong Wuk Kim, Hye Hyun Yoo, Chul Soon Yong, Yu Seok Youn, Kyung Taek Oh, Jun-Pil Jee, Jong Oh Kim, Sung Giu Jin, Han Gon Choi
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1018-1025 (2017)
To develop a novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for a water-insoluble oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) with improved stability and oral bioavailability, numerous S-SNEDDS were prepared with
Externí odkaz:
https://doaj.org/article/75e47abbb4fc4bfdae1a3fb178ddcfd2
Autor:
Fakhar ud Din, Ju Yeon Choi, Dong Wuk Kim, Omer Mustapha, Dong Shik Kim, Raj Kumar Thapa, Sae Kwang Ku, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Han-Gon Choi
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 502-510 (2017)
Intravenously administered for the treatment of rectum cancer, irinotecan produces severe side effects due to very high plasma concentrations. A novel irinotecan-encapsulated double reverse thermosensitive nanocarrier system (DRTN) for rectal adminis
Externí odkaz:
https://doaj.org/article/cee4305d71e74738b78c2d36afc0c4bf