Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Yu S Huang"'
Autor:
Dalin Xiong, Tiancheng Han, Yulong Li, Yuanyuan Hong, Suxing Li, Xi Li, Wenhui Tao, Yu S. Huang, Weizhi Chen, Chunguang Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we proposed a plasma cfDNA-based approach called TOTEM to detect and trace the cancer signal origin (
Externí odkaz:
https://doaj.org/article/8d6589fa390641a9a252fde9aec24d33
Autor:
Dai-Yin Chao, Adriano Silva, Ivan Baxter, Yu S Huang, Magnus Nordborg, John Danku, Brett Lahner, Elena Yakubova, David E Salt
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002923 (2012)
Understanding the mechanism of cadmium (Cd) accumulation in plants is important to help reduce its potential toxicity to both plants and humans through dietary and environmental exposure. Here, we report on a study to uncover the genetic basis underl
Externí odkaz:
https://doaj.org/article/f6a49397c99a47478fb0261642771188
Autor:
Ivan Baxter, Jessica N Brazelton, Danni Yu, Yu S Huang, Brett Lahner, Elena Yakubova, Yan Li, Joy Bergelson, Justin O Borevitz, Magnus Nordborg, Olga Vitek, David E Salt
Publikováno v:
PLoS Genetics, Vol 6, Iss 11, p e1001193 (2010)
The genetic model plant Arabidopsis thaliana, like many plant species, experiences a range of edaphic conditions across its natural habitat. Such heterogeneity may drive local adaptation, though the molecular genetic basis remains elusive. Here, we d
Externí odkaz:
https://doaj.org/article/2f663dec67e34817982ce1620ec8bc88
Autor:
Alexander Platt, Matthew Horton, Yu S Huang, Yan Li, Alison E Anastasio, Ni Wayan Mulyati, Jon Agren, Oliver Bossdorf, Diane Byers, Kathleen Donohue, Megan Dunning, Eric B Holub, Andrew Hudson, Valérie Le Corre, Olivier Loudet, Fabrice Roux, Norman Warthmann, Detlef Weigel, Luz Rivero, Randy Scholl, Magnus Nordborg, Joy Bergelson, Justin O Borevitz
Publikováno v:
PLoS Genetics, Vol 6, Iss 2, p e1000843 (2010)
The population structure of an organism reflects its evolutionary history and influences its evolutionary trajectory. It constrains the combination of genetic diversity and reveals patterns of past gene flow. Understanding it is a prerequisite for de
Externí odkaz:
https://doaj.org/article/5fc1aacda11f4e94aa8273b6aac6e75b
Autor:
Fenglong Bie, Zhijie Wang, Yulong Li, Wei Guo, Yuanyuan Hong, Tiancheng Han, Fang Lv, Shunli Yang, Suxing Li, Xi Li, Peiyao Nie, Shun Xu, Ruochuan Zang, Moyan Zhang, Peng Song, Feiyue Feng, Jianchun Duan, Guangyu Bai, Yuan Li, Qilin Huai, Bolun Zhou, Yu S. Huang, Weizhi Chen, Fengwei Tan, Shugeng Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Multimodal epigenetic characterization of cell-free DNA (cfDNA) could improve the performance of blood-based early cancer detection. However, integrative profiling of cfDNA methylome and fragmentome has been technologically challenging. Here
Externí odkaz:
https://doaj.org/article/1dac2947a89c4d6f857ab60c3f8e4c7c
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Copy number alterations (CNAs), due to their large impact on the genome, have been an important contributing factor to oncogenesis and metastasis. Detecting genomic alterations from the shallow-sequencing data of a low-purity tumo
Externí odkaz:
https://doaj.org/article/8e1c1d18a88145818f2ac4de7ca18f84
Publikováno v:
Journal of Interpersonal Violence. 37:NP23131-NP23155
The #MeToo movement has facilitated a growing awareness in the UK of rape stereotypes but there has been little research on how accurately rape is perceived in this region, especially regarding demographics such as ethnicity and age. This study recru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555f029febcea3700083481dd4f2440c
https://doi.org/10.1177/08862605221076162
https://doi.org/10.1177/08862605221076162
Autor:
Marissa. M. Gaskill, Isabella V. Soluri, Annemarie E. Branks, Alan P. Boka, Michael R. Stadler, Katherine Vietor, Hao-Yu S. Huang, Tyler J. Gibson, Mustafa Mir, Shelby A. Blythe, Melissa M. Harrison
/SummaryThe eukaryotic genome is organized to enable the precise regulation of gene expression required for development. This organization is established during early development when the embryo transitions from a fertilized germ cell to the totipote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f3267f26c9efa30151a8e471cae5ccc
https://doi.org/10.1101/2022.11.29.518380
https://doi.org/10.1101/2022.11.29.518380
Autor:
Jinnan Hu, Cai Jiang, Yu S. Huang, Haodong Chen, Hanying Feng, Donald Freed, Yan Qu, Rui Fan, Zhencheng Su, Weizhi Chen
Liquid biopsy enables identification of low allele frequency (AF) tumor variants and novel clinical applications such as minimum residual disease (MRD) monitoring. However, challenges remain, primarily due to limited sample volume and low read count
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7fa6232e87cc6055344bb047a29c11c
https://doi.org/10.1101/2022.06.03.494742
https://doi.org/10.1101/2022.06.03.494742
Publikováno v:
Computers in Biology and Medicine. 151:106323
Deep learning-based virtual screening methods have been shown to significantly improve the accuracy of traditional docking-based virtual screening methods. In this paper, we developed Deffini, a structure-based virtual screening neural network model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3756059f19fc05a8c4f597403beb635
https://doi.org/10.1016/j.compbiomed.2022.106323
https://doi.org/10.1016/j.compbiomed.2022.106323