Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yu Onozaki"'
Autor:
Masao Tokuda, Mamoru Miyazawa, Takeshi Ohkuma, Hisanori Senboku, Kazuhiko Orito, Yu Onozaki, Takatoshi Nakamura, Akiyoshi Horibata, Nobuhito Kurono, Takashi Tokuhashi
Publikováno v:
Journal of Heterocyclic Chemistry. 50:E48-E54
A variety of alkoxy-substituted benzolactams with a berbine or yohimbane skeleton were prepared from 1-benzyl-1,2,3,4-tetrahydroisoquinolines or 1-benzyl-1,2,3,4-tetrahydro-β-carbolines by a phosphine-free Pd(II)-catalyzed direct aromatic carbonylat
Autor:
Kazuhiko Orito, Shiho Uchiito, Takeshi Ohkuma, Rika Harada, Nobuhito Kurono, Tokuda Masao, Yu Onozaki, Naoto Nishida, Hisanori Senboku
Publikováno v:
European Journal of Organic Chemistry. 2012:366-379
Phosphane-free Pd0-catalyzed intramolecular aromatic amination was studied. o-Halophenethylamines and 3-(o-halophenyl)propylamines were found to be transformed into indolines and quinolines in a catalytic system based on Pd(OAc)2 and Cu(OAc)2 in the
Publikováno v:
The Journal of Organic Chemistry. 74:5486-5495
Methods for synthesis of a ring system characteristic of isoindolobenzazepine alkaloids were studied. Synthesis of lennoxamine and a formal synthesis of chelenine were accomplished in a short route via radical or Pd(0)-catalyzed cyclization as the ke
Autor:
Miho Tomiki, Yu Onozaki, Harumi Kaga, Masao Tokuda, Kazuhiko Orito, Yasuhiro Wada, Shiho Uchiito, Nobuhito Kurono, Eri Kumazawa, Takeshi Ohkuma
Publikováno v:
The Journal of Organic Chemistry. 72:7301-7306
For the synthesis of protopine alkaloids, we studied a reaction sequence based on a ring enlargement of indeno[2,1-a][3]benzazepines by a singlet oxygen oxygenation, followed by conversion of an amide carbonyl group of the resultant 10-membered keto-
Autor:
Yu Onozaki, Naoto Nishida, Kazuhiko Orito, Takeshi Ohkuma, Rika Harada, Nobuhito Kurono, Hisanori Senboku, Tokuda Masao, Shiho Uchiito
Publikováno v:
ChemInform. 43
Various indoles and pyridine-fused four- and pentacycles are prepared by the title methods, involving alkaloid precursors such as (XVI).
Publikováno v:
ChemInform. 41
Methods for synthesis of a ring system characteristic of isoindolobenzazepine alkaloids were studied. Synthesis of lennoxamine and a formal synthesis of chelenine were accomplished in a short route via radical or Pd(0)-catalyzed cyclization as the ke
Autor:
Yoshikazu Iwasawa, Yu Onozaki, Hidehito Kotani, Akiko Watanabe, Kyosuke Haze, Chie Kadowaki, Kaori Kamijo, Morihiro Mitsuya, Toshiaki Tsujino, Hideki Kurihara, Masato Iida, Sachie Otsuki, Takumitsu Machida, Hideya Komatani, Yoko Nakatsuru, Tetsuya Sugimoto, Yoshiyuki Sato
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(16)
A novel class of imidazopyridine derivatives was designed as PLK1 inhibitors. Extensive SAR studies supported by molecular modeling afforded a highly potent and selective compound 36. Compound 36 demonstrated good antitumor efficacy in xenograft nude
Autor:
Harumi Kaga, Shiho Uchiito, Miho Tomiki, Eri Kumazawa, Yasuhiro Wada, Nobuhito Kurono, Takeshi Ohkuma, Kazuhiko Orito, Masao Tokuda, Yu Onozaki
Publikováno v:
ChemInform. 39
Publikováno v:
The Journal of Organic Chemistry. 74:6414-6414