Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Yu Ming Xu"'
Autor:
Ling-Jie Li, Xiao-Ying Sun, Ya-Ru Huang, Shuai Lu, Yu-Ming Xu, Jing Yang, Xi-Xiu Xie, Jie Zhu, Xiao-Yun Niu, Dan Wang, Shi-Yu Liang, Xiao-Yu Du, Sheng-Jie Hou, Xiao-Lin Yu, Rui-Tian Liu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background Deoxyribonuclease 2 (DNase II) plays a key role in clearing cytoplasmic double-stranded DNA (dsDNA). Deficiency of DNase II leads to DNA accumulation in the cytoplasm. Persistent dsDNA in neurons is an early pathological hallmark
Externí odkaz:
https://doaj.org/article/7a9b0bec679c43d4b8d1202c43f3c6dc
Autor:
Hang-hang Zhu, Yun-chao Wang, Liu-chang He, Hai-yang Luo, Ce Zong, Ying-hao Yang, Jing-Hao Wu, Bo Song, Yuan Gao, Yu-ming Xu, Yu-sheng Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This study investigated the correlation of newly identified inflammatory and insulin resistance indices with cerebral amyloid angiopathy (CAA), and explored their potential to differentiate CAA from hypertensive arteriopathy (HA). We retrosp
Externí odkaz:
https://doaj.org/article/94a1cd9078d04b42a058a7570006de1c
Autor:
Zhi-yun Wang, Dong-rui Ma, Meng-jie Li, Yuan-yuan Liang, Zheng-wei Hu, Shuang-jie Li, Chun-yan Zuo, Chen-wei Hao, Yan-mei Feng, Meng-nan Guo, Xiao-yan Hao, Yuan-li Guo, Ke-ke Ma, Li-na Guo, Chan Zhang, Yu-ming Xu, Cheng-yuan Mao, Chang-he Shi
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract This study aimed to investigate the association between irritable bowel syndrome (IBS) and Parkinson’s disease (PD) utilizing prospective cohort study and Mendelian randomization. The dataset contained a substantial cohort of 426,911 parti
Externí odkaz:
https://doaj.org/article/c8a9d1ed7a4a4fb2bfb505c7a67c2d9f
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) are three nervous system diseases that partially overlap clinically and genetically. However, bulk RNA-sequencing did not accurately detect the core p
Externí odkaz:
https://doaj.org/article/c0b88462dead405999d7eb65bb79029c
Autor:
Shuang-jie Li, Jing-jing Shi, Cheng-yuan Mao, Chan Zhang, Ya-fang Xu, Yu Fan, Zheng-wei Hu, Wen-kai Yu, Xiao-yan Hao, Meng-jie Li, Jia-di Li, Dong-rui Ma, Meng-nan Guo, Chun-yan Zuo, Yuan-yuan Liang, Yu-ming Xu, Jun Wu, Shi-lei Sun, Yong-gang Wang, Chang-he Shi
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background While previous genome-wide association studies (GWAS) have identified multiple risk variants for migraine, there is a lack of evidence about how these variants contribute to the development of migraine. We employed an integrative
Externí odkaz:
https://doaj.org/article/12c9f62fbffe4c20a6dd0ef0e69729cf
Publikováno v:
Brain and Behavior, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background SRPK1 is a splicing‐related protein that plays an important role in the development and function of the human brain. This article presents evidence that SRPK1 has distinct spatiotemporal expression patterns enriched in processes
Externí odkaz:
https://doaj.org/article/4f676bc7bbdf418793b4a34ea3f60c77
Publikováno v:
Brain and Behavior, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Ischemic stroke is a disease in which cerebral blood flow is blocked due to various reasons, leading to ischemia, hypoxia, softening, and even necrosis of brain tissues. The level of cortisol is related to the occurrence and progr
Externí odkaz:
https://doaj.org/article/17ece5c4b79d417ca2ef26018c1031f7
Publikováno v:
Neurobiology of Disease, Vol 189, Iss , Pp 106347- (2023)
Cerebral small vessel disease (CSVD) causes 20%–25% of stroke and contributes to 45% of dementia cases worldwide. However, since its early symptoms are inconclusive in addition to the complexity of the pathological basis, there is a rather limited
Externí odkaz:
https://doaj.org/article/a664cf47ce064bfaa2377d98d116c87a
Autor:
Wen-Kai Yu, Yun-Chao Wang, Yuan Gao, Chang-He Shi, Yu Fan, Lu-Lu Yu, Zi-Chen Zhao, Shan-Shan Li, Yu-Ming Xu, Yu-Sheng Li
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract Background A loss-of-function mutation in ATPase phospholipid transporting 11-B (putative) (ATP11B) gene causing cerebral small vessel disease (SVD) in vivo, and a single intronic nucleotide polymorphism in ATP11B: rs148771930 that was assoc
Externí odkaz:
https://doaj.org/article/f7de01b27aa1474ba20d30c265aa7045
Autor:
Ying-hao Yang, Shan-shan Li, Yun-chao Wang, Lu-lu Yu, Hang-hang Zhu, Jing-hao Wu, Wen-kai Yu, Lu An, Wen-xin Yuan, Yan Ji, Yu-ming Xu, Yuan Gao, Yu-sheng Li
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundCerebral small vessel disease (CSVD) is common in the elderly population. Neutrophil gelatinase-associated lipocalin (NGAL) is closely related to cardiovascular and cerebrovascular diseases. NGAL causes pathological changes, such as damage
Externí odkaz:
https://doaj.org/article/24baf8dd77404443a808ef8f91082231