Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yu Larpin"'
Autor:
Hervé Besançon, Viktoriia Babiychuk, Yu Larpin, René Köffel, Dominik Schittny, Lara Brockhus, Lucy J. Hathaway, Parham Sendi, Annette Draeger, Eduard Babiychuk
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of patho
Externí odkaz:
https://doaj.org/article/ef137a52471f4d6bbf852b1b4d4f936b
Publikováno v:
Cells, Vol 11, Iss 1, p 166 (2022)
The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their vir
Externí odkaz:
https://doaj.org/article/1a6c0cf01d9f4eb68bc7fbae3a765c70
Publikováno v:
Toxins, Vol 13, Iss 2, p 126 (2021)
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small
Externí odkaz:
https://doaj.org/article/5850a966b2c24dbba6cd675c17b075bb
Autor:
René Köffel, Heidi Wolfmeier, Yu Larpin, Hervé Besançon, Roman Schoenauer, Viktoria S. Babiychuk, Patrick Drücker, Thomas Pabst, Timothy J. Mitchell, Eduard B. Babiychuk, Annette Draeger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell
Externí odkaz:
https://doaj.org/article/ab204a27906c4eb7b16198098641d220
Autor:
Yu Larpin, Frank Oechslin, Philippe Moreillon, Grégory Resch, José Manuel Entenza, Stefano Mancini
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192507 (2018)
The recent rise of multidrug-resistant Gram-negative bacteria represents a serious threat to public health and makes the search for novel effective alternatives to antibiotics a compelling need. Bacteriophage (Phage) lysins are enzymes that hydrolyze
Externí odkaz:
https://doaj.org/article/7442f6c46ee94e4ca3c179e537cc3241
Autor:
Eduard B. Babiychuk, Yu Larpin, Annette Draeger, Mircea-Ioan Iacovache, Victoriia S. Babiychuk, Hervé Besançon, Benoît Zuber, René Köffel
Publikováno v:
The FASEB Journal. 34:1665-1678
Bacterial infectious diseases can lead to death or to serious illnesses. These outcomes are partly the consequence of pore‐forming toxins, which are secreted by the pathogenic bacteria (eg, pneumolysin of Streptococcus pneumoniae). Pneumolysin bind
Publikováno v:
Toxins
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small
Autor:
Parham Sendi, Dominik Schittny, Viktoriia S. Babiychuk, Yu Larpin, René Köffel, Eduard B. Babiychuk, Annette Draeger, Lara Brockhus, Lucy J. Hathaway, Hervé Besançon
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Nanobiotechnology
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), p. 46. BioMed Central 10.1186/s12951-021-00775-x
Journal of Nanobiotechnology
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), p. 46. BioMed Central 10.1186/s12951-021-00775-x
Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of pathogen clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb5557779461e243883cb8371dabbc
https://doi.org/10.21203/rs.3.rs-52770/v1
https://doi.org/10.21203/rs.3.rs-52770/v1
Autor:
Roger Stephan, Jan Dobias, Yu Larpin, Jean-Yves Madec, Jean-Winoc Decousser, Patrice Nordmann, Laurent Poirel
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 90:7-10
The Rapid Polymyxin NP test has been recently developed to rapidly detect polymyxin resistance in Enterobacteriaceae. Here we evaluated this test for detecting MCR-1/MCR-2-producing Enterobacteriaceae using a collection of 70 non-redundant strains ei
Autor:
Elita Avota, René Köffel, Eduard B. Babiychuk, Roman Schoenauer, Burkhard Kleuser, Viktoriia S. Babiychuk, Patrick Drücker, Sibylle Schneider-Schaulies, Annette Draeger, Yu Larpin, Fabian Schumacher
Bacterial pore-forming toxins compromise plasmalemmal integrity, leading to Ca2+ influx, leakage of the cytoplasm, and cell death. Such lesions can be repaired by microvesicular shedding or by the endocytic uptake of the injured membrane sites. Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e7c7a19e351c499664ca4a26c9ca1f