ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.

Autor: Pozner A; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Li L; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Verma SP; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Wang S; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA., Barrott JJ; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Nelson ML; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Yu JSE; Department of Pathology, University of British Columbia, Vancouver, BC, Canada., Negri GL; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Colborne S; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Hughes CS; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada., Zhu JF; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Lambert SL; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Carroll LS; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Smith-Fry K; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Stewart MG; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA., Kannan S; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Jensen B; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., John CM; Department of Microbiology, Immunology and Infectious Disease, University of Calgary, Calgary, AB, Canada., Sikdar S; Department of Microbiology, Immunology and Infectious Disease, University of Calgary, Calgary, AB, Canada., Liu H; Department of Microbiology, Immunology and Infectious Disease, University of Calgary, Calgary, AB, Canada., Dang NH; Department of Oncology, Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Bourdage J; Department of Oncology, Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Li J; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Vahrenkamp JM; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Mortenson KL; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Groundland JS; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Wustrack R; Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA., Senger DL; Department of Oncology, Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.; Department of Oncology, McGill University and Lady Davis Institute for Medical Research, Montreal, QC, Canada., Zemp FJ; Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA., Mahoney DJ; Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA., Gertz J; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Zhang X; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Lazar AJ; Departments of Anatomic Pathology, Translational Molecular Pathology and Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hirst M; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.; Department of Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada., Morin GB; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada.; 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Publikováno v: Nature communications [Nat Commun] 2024 Feb 07; Vol. 15 (1), pp. 1165. Date of Electronic Publication: 2024 Feb 07.

The epigenomics of sarcoma.

Autor: Nacev BA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; The Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA., Jones KB; Department of Orthopaedics, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA., Intlekofer AM; Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yu JSE; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Allis CD; The Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA., Tap WD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nielsen TO; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. torsten@mail.ubc.ca.

Publikováno v: Nature reviews. Cancer [Nat Rev Cancer] 2020 Oct; Vol. 20 (10), pp. 608-623. Date of Electronic Publication: 2020 Aug 11.