Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Yu Hung Hsu"'
Autor:
Ching Ying Huang, Martin W. Nicholson, Jyun Yuan Wang, Chien Yu Ting, Ming Heng Tsai, Yu Che Cheng, Chun Lin Liu, Darien Z.H. Chan, Yi Chan Lee, Ching Chuan Hsu, Yu Hung Hsu, Chiou Fong Yang, Cindy M.C. Chang, Shu Chian Ruan, Po Ju Lin, Jen Hao Lin, Li Lun Chen, Marvin L. Hsieh, Yuan Yuan Cheng, Wan Tseng Hsu, Yi Ling Lin, Chien Hsiun Chen, Yu Hsiang Hsu, Ying Ta Wu, Timothy A. Hacker, Joseph C. Wu, Timothy J. Kamp, Patrick C.H. Hsieh
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114748- (2024)
Externí odkaz:
https://doaj.org/article/9ae5935c5e08433db79b9871e1e395fe
Autor:
Ching Ying Huang, Martin W. Nicholson, Jyun Yuan Wang, Chien Yu Ting, Ming Heng Tsai, Yu Che Cheng, Chun Lin Liu, Darien Z.H. Chan, Yi Chan Lee, Ching Chuan Hsu, Yu Hung Hsu, Chiou Fong Yang, Cindy M.C. Chang, Shu Chian Ruan, Po Ju Lin, Jen Hao Lin, Li Lun Chen, Marvin L. Hsieh, Yuan Yuan Cheng, Wan Tseng Hsu, Yi Ling Lin, Chien Hsiun Chen, Yu Hsiang Hsu, Ying Ta Wu, Timothy A. Hacker, Joseph C. Wu, Timothy J. Kamp, Patrick C.H. Hsieh
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110643- (2022)
Summary: In this study, we establish a population-based human induced pluripotent stem cell (hiPSC) drug screening platform for toxicity assessment. After recruiting 1,000 healthy donors and screening for high-frequency human leukocyte antigen (HLA)
Externí odkaz:
https://doaj.org/article/da8bc8cb1a58446e870b6a5639aa6740
Autor:
Martin W. Nicholson, Ching-Ying Huang, Jyun-Yuan Wang, Chien-Yu Ting, Yu-Che Cheng, Darien Z. H. Chan, Yi-Chan Lee, Ching-Chuan Hsu, Yu-Hung Hsu, Cindy M. C. Chang, Marvin L. Hsieh, Yuan-Yuan Cheng, Yi-Ling Lin, Chien-Hsiun Chen, Ying-Ta Wu, Timothy A. Hacker, Joseph C. Wu, Timothy J. Kamp, Patrick C. H. Hsieh
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 765 (2022)
Since December 2019, the novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected ~435 million people and caused ~6 million related deaths as of March 2022. To combat COVID-19, th
Externí odkaz:
https://doaj.org/article/281becb748f34355a75c8da991a28a2e
Autor:
Shih-Ping Liu, Yu-Hung Hsu, Ching-Ying Huang, Ming-Ching Ho, Yu-Che Cheng, Cheng-Hao Wen, Huai-En Lu, Chon-Haw Tsai, Woei-Cherng Shyu, Patrick C.H. Hsieh
Publikováno v:
Stem Cell Research, Vol 28, Iss , Pp 39-43 (2018)
Sialidosis is a rare autosomal recessive disorder that affects the intralysosomal catabolism of sialylated glycoconjugates and is involved in cellular immune response. Mutations in NEU1, which encodes the sialidase enzyme, result in sialidosis. Siali
Externí odkaz:
https://doaj.org/article/c1bf9b454a24419c8c5994688cc5aa91
Autor:
Yu-Che Cheng, Ching-Ying Huang, Ming-Ching Ho, Yu-Hung Hsu, Shih-Han Syu, Huai-En Lu, Han-I Lin, Chin-Hsien Lin, Patrick C.H. Hsieh
Publikováno v:
Stem Cell Research, Vol 28, Iss , Pp 1-5 (2018)
Leucine rich repeat kinase (LRRK2) is the most prevalent genetic cause for Parkinson's disease. LRRK2 p.G2385R is an Asian specific genetic risk factor for sporadic Parkinson's disease. We generated two induced pluripotent stem cells (iPSCs), IBMS-iP
Externí odkaz:
https://doaj.org/article/f1d5cc0ddc224aa8b86c5b0dbe21abff
Autor:
Yu-Ting Wu, Yu-Hung Hsu, Ching-Ying Huang, Ming-Ching Ho, Yu-Che Cheng, Cheng-Hao Wen, Hui-Wen Ko, Huai-En Lu, Yen-Chun Chen, Chia-Ling Tsai, Yi-Chao Hsu, Yau-Huei Wei, Patrick C.H. Hsieh
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 10-14 (2018)
Mitochondrial defects are associated with clinical manifestations from common diseases to rare genetic disorders. Myoclonus epilepsy associated with ragged-red fibers (MERRF) syndrome results from an A to G transition at nucleotide position 8344 in t
Externí odkaz:
https://doaj.org/article/1ac8a05a9b114e69884c09e1c5764f87
Autor:
Jia-Jung Lee, Ming-Ching Ho, Ching-Ying Huang, Cheng-Hao Wen, Yu-Che Cheng, Yu-Hung Hsu, Daw-Yang Hwang, Huai-En Lu, Hung-Chun Chen, Patrick C.H. Hsieh
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 83-87 (2017)
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent monogenic kidney disorder leading to kidney failure. We generated induced pluripotent stem cells (iPSCs) from a 37-year-old man carrying a PKD1 Q533X mutation who suffered fro
Externí odkaz:
https://doaj.org/article/ea7fa7e2ff9947f89198d0e3caf78711
Autor:
Chin-Hsien Lin, Yu-Che Cheng, Han-I Lin, Ming-Ching Ho, Yu-Hung Hsu, Cheng-Hao Wen, Hui-Wen Ko, Huai-En Lu, Ching-Ying Huang, Patrick C.H. Hsieh
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 123-127 (2017)
Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by interactions between genetic and environmental factors. Leucine rich repeat kinase (LRRK2) is the most prevalent mutation in autosomal-dominant inheritance of PD. Here, we
Externí odkaz:
https://doaj.org/article/b66f18682c7a433d8fb30e601c600330
Autor:
Ming-Ching Ho, Ching-Ying Huang, Jia-Jung Lee, Shih-Han Hsu, Yu-Che Cheng, Yu-Hung Hsu, Daw-Yang Hwang, Huai-En Lu, Hung-Chun Chen, Patrick C.H. Hsieh
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 38-41 (2017)
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most commonly inherited forms of polycystic kidney disease, and is characterized by the growth of numerous cysts in both kidneys. Here we generated an induced pluripotent stem cell (i
Externí odkaz:
https://doaj.org/article/00e0c51ee16345da8d4d2b6ad197dfcb