Zobrazeno 1 - 10
of 594
pro vyhledávání: '"Yu Hong, Li"'
Autor:
Ying Jin, Run-Jie Huang, Wen-Long Guan, Zhi-Qiang Wang, Zong-Jiong Mai, Yu-Hong Li, Jian Xiao, Xing Zhang, Qi Zhao, Shi-Fu Chen, Ming Liu, Yan-Xia Shi, Feng Wang, Rui-Hua Xu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Patients carrying mutations in polymerase epsilon/polymerase delta have shown positive responses to immune checkpoint inhibitors. Yet, prospective trials exploring the efficacy in those with polymerase epsilon/polymerase delta mutations are
Externí odkaz:
https://doaj.org/article/e6f6d0c5d1ef434bbde38b71bbd7b039
Autor:
Zi-yi Zhang, Yu-hong Li
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Introduction Skeletal muscle dysfunction is a significant factor contributing to exercise limitation in patients with chronic obstructive pulmonary disease (COPD). Although exercise training is often recommended to enhance patient outcomes, there con
Externí odkaz:
https://doaj.org/article/5a3ffaa8f5834cdc98b506c819d70df0
Autor:
Zi-Jing Li, William Pat Fong, Dong-Sheng Zhang, Hui-Yan Luo, Dong-Liang Chen, Yan-Yu Cai, Zhi-Gang Chen, Jian-Li Duan, Zi-Yao Huang, Yu-Ting Lu, Xiao-Xia Huang, Yu-Hong Li, De-Shen Wang
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract Anaplastic lymphoma kinase (ALK) fusion-positive colorectal cancer (CRC) is a rare and chemotherapy-refractory subtype that lacks established and effective treatment strategies. Additionally, the efficacy and safety of ALK inhibitors (ALKi)
Externí odkaz:
https://doaj.org/article/bbdc714779f84f3980277043828d8a35
Autor:
De-Shen Wang, Chao Ren, Shan-Shan Li, William Pat Fong, Xiao-Jun Wu, Jian Xiao, Bin-Kui Li, Yun Zheng, Pei-Rong Ding, Gong Chen, Miao-Zhen Qiu, Zhi-Qiang Wang, Feng-Hua Wang, Hui-Yan Luo, Feng Wang, Xiao-Zhong Wang, Ling-Yun Wang, De-Jin Xie, Tao Chen, Li-Ren Li, Zhen-Hai Lu, Xiao-Hui Zhai, Tian-Shu Liu, Ying Yuan, Jia-Qi Chen, Qiong Tan, Zhi-Zhong Pan, De-Sen Wan, Rong Zhang, Yun-Fei Yuan, Rui-Hua Xu, Yu-Hong Li
Publikováno v:
PLoS Medicine, Vol 21, Iss 5, p e1004389 (2024)
BackgroundIt remains unclear whether intensification of the chemotherapy backbone in tandem with an anti-EGFR can confer superior clinical outcomes in a cohort of RAS/BRAF wild-type colorectal cancer (CRC) patients with initially unresectable colorec
Externí odkaz:
https://doaj.org/article/b9e6a45661f549378ef2d8ab851edf5e
Autor:
Renjing Zhang, Yang Yang, Chunfang Hu, Mayan Huang, Wenjian Cen, Dongyi Ling, Yakang Long, Xin-Hua Yang, Boheng Xu, Junling Peng, Sujie Wang, Weijie Zhu, Mingbiao Wei, Jiaojiao Yang, Yuxia Xu, Xu Zhang, Jiangjun Ma, Fang Wang, Hongtu Zhang, Peiqing Ma, Xiaojun Zhu, Guohui Song, Li-Yue Sun, De-Shen Wang, Feng-Hua Wang, Yu-Hong Li, Sandro Santagata, Qin Li, Yan-Fen Feng, Ziming Du
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Solitary fibrous tumors (SFTs) are rare mesenchymal tumors with unpredictable evolution and with a recurrence or metastasis rate of 10-40%. Current medical treatments for relapsed SFTs remain ineffective. Here, we identify potential therapeu
Externí odkaz:
https://doaj.org/article/40b85ffd685f4b10bbdd4c6df9fa3b0a
Publikováno v:
Translational Neuroscience, Vol 14, Iss 1, Pp 1577-90 (2023)
Baicalin has been shown to promote spatial learning and neural regeneration, which might increase the differentiation of neural stem cells in Alzheimer’s disease (AD) rat models. We aimed to study the role of baicalin on neuronal pentraxin-1 (NPTX-
Externí odkaz:
https://doaj.org/article/9e340668cfc64520bbf4633f11df6a46
Autor:
Zhi-Gang Chen, Xiao-Meng Ji, Yu-Xia Xu, William Pat Fong, Xiao-Yun Liu, Jie-Ying Liang, Qiong Tan, Lei Wen, Yan-Yu Cai, De-Shen Wang, Yu-Hong Li
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Patients with initially unresectable colorectal cancer liver metastases (IU-CRLM) might benefit from using an effective systemic treatment followed by resection of liver metastases but the curative success rate is quite low. Indeed, nearl
Externí odkaz:
https://doaj.org/article/ccaf6294ee4a4f3d94a0190ab3a31533
Autor:
Zi-Yao Huang, Lei Wen, Liu-Fang Ye, Yu-Ting Lu, William Pat Fong, Ren-Jing Zhang, Si-Xian Wu, Zhi-Gang Chen, Yan-Yu Cai, Rui-Hua Xu, Yu-Hong Li, Zi-Ming Du, De-Shen Wang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Transmembrane E3 ubiquitin ligase ( RNF43 ) mutations are present in approximately 6–18% of colorectal cancers (CRC) and could enhance Wnt/β-catenin signaling, which is emerging as a promising therapeutic target. This study aims to inv
Externí odkaz:
https://doaj.org/article/d267fbf1f23c40f6a8146f578616f919
Autor:
Xiao-Hui Liu, Zhi-Juan Cao, Li-Wei Chen, Dong-Lan Zhang, Xiao-Xian Qu, Yu-Hong Li, Yu-Ping Tang, Yi-Rong Bao, Hao Ying
Publikováno v:
Public Health Nutrition, Vol 26, Pp 1014-1021 (2023)
Abstract Objective: To investigate the association between folate levels and the risk of gestational diabetes mellitus (GDM) risk during the whole pregnancy. Design: In this retrospective cohort study of pregnant women, serum folate levels were me
Externí odkaz:
https://doaj.org/article/ab1060132bf54090acf2f45f35aaf80d
Autor:
Li Zhang, Jun Huang, Lu Dai, Gang Zhu, Xiao-Lin Yang, Zeng He, Yu-Hong Li, Hui Yang, Chun-Qing Zhang, Kai-Feng Shen, Ping Liang
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundFocal cortical dysplasia (FCD) IIb and tuberous sclerosis complex (TSC) are common causes of drug-resistant epilepsy in children. However, the etiologies related to the development of FCD IIb and TSC are not fully understood. α-synuclein (
Externí odkaz:
https://doaj.org/article/7a234aca22ca4d9f828eecde59085784