Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yu Harayama"'
Autor:
Yu Harayama, Daigo Kamimura, Masako Yoshida, Kouji Otani, Hiromichi Fujioka, Yasuyuki Kita, Yasufumi Wada, Noriko Endo
Publikováno v:
Tetrahedron. 65:1059-1062
The first asymmetric total synthesis of prianosin B ( 1 ) is described. Formation of the 16,17-dehydropyrroloiminoquinone skeleton from the pyrroloiminoquinone unit is a key step in this synthesis. Thus, the detosylation and dehydrogenation reactions
Publikováno v:
Chemistry - A European Journal. 12:4893-4899
Hypervalent iodine(III) reagents are readily available, easy to handle, and have a low toxicity and similar reactivities to those of heavy metal reagents, and hence they are used for various oxidative reactions. The oxidative cleavage of alkynes or c
Autor:
Yu Harayama, Yasuyuki Kita
Publikováno v:
Current Organic Chemistry. 9:1567-1588
Publikováno v:
Tetrahedron Letters. 42:6899-6902
A new method for preparing p-quinone derivatives from phenol ether derivatives in water using the hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA) was developed. The present reaction proceeds in good to excellent yields
Autor:
Yasufumi Wada, Daigo Kamimura, Noriko Endo, Yasuyuki Kita, Kouji Otani, Yu Harayama, Masako Yoshida, Hiromichi Fujioka
Publikováno v:
Organic letters. 11(18)
Discorhabdin A (1) exhibits a strong cytotoxic activity in vitro, but it is difficult to synthesize and handle due to the instability of its highly strained N,S-acetal structure. We then designed the analogues of discorhabdin A which also have strong
Autor:
Yu Harayama, Masako Yoshida, Yasuyuki Kita, Daigo Kamimura, Hiromichi Fujioka, Noriko Endo, Kouji Otani, Yasufumi Wada
Publikováno v:
ChemInform. 40
The first asymmetric total synthesis of prianosin B ( 1 ) is described. Formation of the 16,17-dehydropyrroloiminoquinone skeleton from the pyrroloiminoquinone unit is a key step in this synthesis. Thus, the detosylation and dehydrogenation reactions
Autor:
Yasuyuki Kita, Yu Harayama, Yorito Kiyono, Masahiro Egi, Hirofumi Tohma, Minako Iwata, Miki Hashizume
Publikováno v:
Journal of the American Chemical Society. 125(37)
The first stereoselective total synthesis of a potent antitumor alkaloid, discorhabdin A (1), which is a unique sulfur-containing pyrroloiminoquinone alkaloid, is described. The key step in the stereocontrolled total synthesis of 1 involves both a di
Publikováno v:
Chemical communications (Cambridge, England). (13)
The use of hypervalent iodine(III) reagents allowed us to develop the novel and efficient direct synthesis of N,O-acetal compounds via the oxidative fragmentation reaction of alpha-amino acids or alpha-amino alcohols; furthermore, we succeeded in dev
Autor:
Masahiro Egi, Hirofumi Tohma, Minako Iwata, Yorito Kiyono, Miki Hashizume, Yasuyuki Kita, Yu Harayama
Publikováno v:
ChemInform. 35
The first stereoselective total synthesis of a potent antitumor alkaloid, discorhabdin A (1), which is a unique sulfur-containing pyrroloiminoquinone alkaloid, is described. The key step in the stereocontrolled total synthesis of 1 involves both a di