Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Yu FUJIWARA"'
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Perioperative use of immune checkpoint blockade (ICB) improves survival in patients with early-stage cancer. Treatment-related adverse events (AEs), frequently involve the endocrine system which may increase perioperative complications an
Externí odkaz:
https://doaj.org/article/0f635a3cff614116978c750a76fefb3e
Autor:
Yu Fujiwara, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mary K. Nesline, Jeffrey M. Conroy, Paul DePietro, Sarabjot Pabla, Scott M. Lippman, Razelle Kurzrock
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109632- (2024)
Summary: Indoleamine 2,3-dioxygenase 1 (IDO1), which catabolizes tryptophan, is a potential target to unlock the immunosuppressive tumor microenvironment. Correlations between IDO1 and immune checkpoint inhibitor (ICI) efficacy remain unclear. Herein
Externí odkaz:
https://doaj.org/article/9df1b09acc8f49f69d386a55f32c1121
Autor:
Taku Maruki, Tomohiro Utsumi, Masahiro Takeshima, Yu Fujiwara, Marie Matsui, Yumi Aoki, Hiroyuki Toda, Norio Watanabe, Koichiro Watanabe, Yoshikazu Takaesu
Publikováno v:
International Journal of Bipolar Disorders, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Background The efficacy and safety of adjunctive therapy are unclear in bipolar depression. In this systematic review and meta-analysis, we aimed to evaluate the efficacy and safety of second-generation antipsychotic, lamotrigine, lithium, o
Externí odkaz:
https://doaj.org/article/9bddb373f9c3412fbbf93318835650a7
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 68-78 (2022)
Mutations of RAS are commonly seen in human cancers, especially in lung, colorectal, and pancreatic adenocarcinoma. Despite huge effort for decades, targeting RAS mutations has been ‘‘undruggable’’ because of the molecular instability of RAS
Externí odkaz:
https://doaj.org/article/e85e1670588a47f2a255abbf721e6157
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Platinum-doublet chemotherapy has been conventionally used for patients with advanced gastroenteropancreatic (GEP) neuroendocrine carcinoma (NEC) but evidence of chemotherapy is based on studies with small sample sizes and remains
Externí odkaz:
https://doaj.org/article/a99f6891e4b1405385c7476c94ab15f3
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-7 (2021)
Abstract Background TAFRO (thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly) syndrome is a recently recognized disease with a variety of presentations of variable severity. In acute settings, this disease
Externí odkaz:
https://doaj.org/article/5dcc3c9498de46329f0ab8aadd7844d2
Autor:
Kohei Somekawa, Nobuyuki Horita, Ayami Kaneko, Yoichi Tagami, Nobuhiko Fukuda, Hiromi Matsumoto, Ho Namkoong, Yu Fujiwara, Kaoru Minegishi, Takeshi Fukumoto, Keisuke Watanabe, Yu Hara, Nobuaki Kobayashi, Takeshi Kaneko
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: No meta-analysis has assessed the pooled frequencies of adverse events (AEs) induced by concomitant nivolumab plus ipilimumab regimen for anticancer-medications-naïve malignancies. Furthermore, no meta-analysis has compared detailed safe
Externí odkaz:
https://doaj.org/article/74a20f8c7cdd4f54a06139cee903b609
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Coral reefs are complex ecosystems composed of many interacting species. One ecologically important group consists of zoantharians, which are closely related to reef-building corals. Like corals, zoantharians form mutualistic symbioses with dinoflage
Externí odkaz:
https://doaj.org/article/2df8ad1e8c0645dc94dbb7e43f74df6e
Publikováno v:
Journal of Medical Case Reports, Vol 12, Iss 1, Pp 1-7 (2018)
Abstract Background TAFRO syndrome, which was first reported in 2010 in Japan, is a relatively rare disease characterized by thrombocytopenia, anasarca, fever, renal impairment, reticulin fibrosis, and organomegaly. Although this disease is considere
Externí odkaz:
https://doaj.org/article/123bb774cc434bf1a744069e14c973b3
Publikováno v:
Urology Case Reports, Vol 24, Iss , Pp - (2019)
It is known that prostate cancer usually presents as adenocarcinoma, frequently metastasizes to bone, appears osteoblastic on radiographs, and shows elevated PSA. Herein, we describe a case of an 80-year-old man diagnosed with prostate cancer present
Externí odkaz:
https://doaj.org/article/aa356445c70a4763a6d701e451b1630b