Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yu Angell"'
Autor:
Na Cr, David D. Roberts, Yu Angell, Nguyen At, Kevin Burgess, Shi Q, Nancy Smyth Templeton, Brunicardi Fc, Deng D
Publikováno v:
Gene therapy
We have developed a multi-disciplinary approach combining molecular biology, delivery technology, combinatorial chemistry and reversible masking to create improved systemic, targeted delivery of plasmid DNA while avoiding nonspecific uptake in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab783be0d678a32acd03bb2eeba75b1
http://europepmc.org/articles/PMC2923228
http://europepmc.org/articles/PMC2923228
Autor:
Yu-Chin Li, Jennifer Moscowicz, Dianjun Chen, Yu Angell, Fouad Brahimi, Kevin Burgess, H. Uri Saragovi
Publikováno v:
ACS Chemical Biology. 4:769-781
This study was initiated to find small molecule ligands that would induce a functional response when docked with neurotrophin Trk receptors. “Minimalist” mimics of β-turns were designed for this purpose. These mimics are: (i) rigid, yet easily f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d76b84ef1082046c516ad00dc7da8d
https://doi.org/10.1021/cb9001415
https://doi.org/10.1021/cb9001415
Publikováno v:
Journal of the American Chemical Society. 130:556-565
Piperidine-functionalized, 1,4-disubstituted-1,2,3-triazoles of generic structure 1 were conceived as "minimalist" mimics of peptidic beta-turn structures. Key features of these molecules include (i) the possibility of incorporating amino acid side c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81762dcce3049326cb5ef115e505f985
https://doi.org/10.1021/ja074717z
https://doi.org/10.1021/ja074717z
Autor:
Kevin Burgess, Yu Angell
Publikováno v:
Angewandte Chemie. 119:3723-3725
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d94a35cf1cfcf8065114273c3077f5
https://doi.org/10.1002/ange.200700399
https://doi.org/10.1002/ange.200700399
Autor:
Kevin Burgess, Yu Angell
Publikováno v:
ChemInform. 39
This critical review concerns the impact of copper-mediated alkyne–azide cycloadditions on peptidomimetic studies. It discusses how this reaction has been used to insert triazoles into peptide chains, to link peptides to other functionalities (e.g.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143d8ce892d258ad8faa6e6a5f1d7fee
https://doi.org/10.1002/chin.200801239
https://doi.org/10.1002/chin.200801239
Autor:
Kevin Burgess, Yu Angell
Publikováno v:
The Journal of organic chemistry. 70(23)
[Structure: see text]. Copper-catalyzed azide alkyne cycloadditions of the linear substrates 1 were used to form the cyclic derivatives 2. Computational, NMR, and CD analyses of these compounds indicate that their most favorable conformational states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d607246c376421b892c5d9158ce47f
https://pubmed.ncbi.nlm.nih.gov/16268639
https://pubmed.ncbi.nlm.nih.gov/16268639
Autor:
Kevin Burgess, Yu Angell
Publikováno v:
Chemical Society Reviews. 36:1674
This critical review concerns the impact of copper-mediated alkyne-azide cycloadditions on peptidomimetic studies. It discusses how this reaction has been used to insert triazoles into peptide chains, to link peptides to other functionalities (e.g. c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8eb3846430f48458858276c2a74494
https://doi.org/10.1039/b701444a
https://doi.org/10.1039/b701444a
Autor:
Angell, Yu, Burgess, Kevin
Publikováno v:
Angewandte Chemie International Edition; May2007, Vol. 46 Issue 20, p3649-3651, 3p