Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Yu‑Hsin Chiu"'
Autor:
Jascinta P. Santavanond, Yu-Hsin Chiu, Rochelle Tixeira, Zonghan Liu, Jeremy K. Y. Yap, Kaiwen W. Chen, Chen-Lu Li, Yi-Ru Lu, Joan Roncero-Carol, Esteban Hoijman, Stephanie F. Rutter, Bo Shi, Gemma F. Ryan, Amy L. Hodge, Sarah Caruso, Amy A. Baxter, Dilara C. Ozkocak, Chad Johnson, Zoe I. Day, Alyce J. Mayfosh, Mark D. Hulett, Thanh K. Phan, Georgia K. Atkin-Smith, Ivan K. H. Poon
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-12 (2024)
Abstract Discovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions such as cancer and infectious d
Externí odkaz:
https://doaj.org/article/62a57fe64f944d87ab3862e5bd598553
Autor:
Yu-Hsin Chiu, Christopher B. Medina, Catherine A. Doyle, Ming Zhou, Adishesh K. Narahari, Joanna K. Sandilos, Elizabeth C. Gonye, Hong-Yu Gao, Shih Yi Guo, Mahmut Parlak, Ulrike M. Lorenz, Thomas P. Conrads, Bimal N. Desai, Kodi S. Ravichandran, Douglas A. Bayliss
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Pannexin 1 (PANX1) is a membrane channel mediating release of signaling molecules to the extracellular space. PANX1 can be activated by GPCRs. Here, the authors elucidate a non-canonical channel activation pathway by α1-adrenergic receptor that invo
Externí odkaz:
https://doaj.org/article/cbaa0bf914904995ab6ca9e837145a21
Autor:
Chi-Chung Chen, Chih-Cheng Lai, Hui-Ling Huang, Yu-Ting Su, Yu-Hsin Chiu, Han-Siong Toh, Shyh-Ren Chiang, Yin-Ching Chuang, Ying-Chen Lu, Hung-Jen Tang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 3, Pp 447-456 (2021)
Background: This study aims to investigate the antimicrobial ability and mechanism analysis of Lactobacillus species against carbapenemase-producing Enterobacteriaceae (CPE). Methods: Five Lactobacillus spp. strains and 18 CPE clinical isolates were
Externí odkaz:
https://doaj.org/article/3bf435fe0a3441ba92b0da9c7774ef71
Autor:
Kuan-Sheng Wu, Ling-Shan Syue, Aristine Cheng, Ting-Yu Yen, Hsien-Meng Chen, Yu-Hsin Chiu, Yu-Lung Hsu, Chun-Hsiang Chiu, Ting-Yi Su, Wan-Lin Tsai, Wei-Yu Chen, Chung-Hao Huang, Huei-Min Hung, Ling-Ju Huang, Hong-Jie Kuo, Pei-Chin Lin, Ching-Hsiang Yang, Pi-Lien Hong, Susan Shin-Jung Lee, Yao-Shen Chen, Yung-Ching Liu, Li-Ming Huang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 53, Iss 2, Pp 191-208 (2020)
Clostridioides difficile infection (CDI) is a major enteric disease associated with antibiotic use and a leading cause of hospital-acquired infections worldwide. This is the first guideline for treatment of CDI in Taiwan, aiming to optimize medical c
Externí odkaz:
https://doaj.org/article/234be927bb864d6792a2fbc43a02c9bb
Autor:
Hung-Jen Tang, Chih-Cheng Lai, Chi-Chung Chen, Chun-Cheng Zhang, Tzu-Chieh Weng, Yu-Hsin Chiu, Han-Siong Toh, Shyh-Ren Chiang, Wen-Liang Yu, Wen-Chien Ko, Yin-Ching Chuang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 52, Iss 2, Pp 273-281 (2019)
Background/Purpose: In vitro studies of the combination of an aminoglycoside with tigecycline or doxycycline against Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae isolates are rarely published. The goal of this study was to evalua
Externí odkaz:
https://doaj.org/article/cb1a97cccdae435aa17ccef13cbe579a
Autor:
Adishesh K Narahari, Alex JB Kreutzberger, Pablo S Gaete, Yu-Hsin Chiu, Susan A Leonhardt, Christopher B Medina, Xueyao Jin, Patrycja W Oleniacz, Volker Kiessling, Paula Q Barrett, Kodi S Ravichandran, Mark Yeager, Jorge E Contreras, Lukas K Tamm, Douglas A Bayliss
Publikováno v:
eLife, Vol 10 (2021)
Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and other cellular metabolites for local intercellular signaling. However, to date, there has bee
Externí odkaz:
https://doaj.org/article/c4cc7f86651745e69bab242b4d3678d0
Autor:
Hung-Jen Tang, Chi-Chung Chen, Chih-Cheng Lai, Chun-Cheng Zhang, Tzu-Chieh Weng, Yu-Hsin Chiu, Han-Siong Toh, Shyh-Ren Chiang, Wen-Liang Yu, Wen-Chien Ko, Yin-Ching Chuang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 51, Iss 1, Pp 76-81 (2018)
Background/purpose: The aim of this study is to investigate the role of tigecycline in Vibrio vulnificus infection. Methods: Eight randomly selected clinical V. vulnificus isolates were studied to obtain the minimal inhibitory concentrations (MICs) o
Externí odkaz:
https://doaj.org/article/39ee2cbb743748cf9e393b96f6cc4131
Autor:
Yu-Hsin Chiu, Xueyao Jin, Christopher B. Medina, Susan A. Leonhardt, Volker Kiessling, Brad C. Bennett, Shaofang Shu, Lukas K. Tamm, Mark Yeager, Kodi S. Ravichandran, Douglas A. Bayliss
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Pannexins are oligomeric plasma membrane channels that allow permeation of ions and large molecules. Here the authors show that human Pannexin 1 activation is a multistep event, where modification of each monomer opens the channel to a unique conduct
Externí odkaz:
https://doaj.org/article/2fd253debe324fffb44a894dc4d37c5c
Autor:
Samantha E. Adamson, Akshaya K. Meher, Yu-hsin Chiu, Joanna K. Sandilos, Nathaniel P. Oberholtzer, Natalie N. Walker, Stefan R. Hargett, Scott A. Seaman, Shayn M. Peirce-Cottler, Brant E. Isakson, Coleen A. McNamara, Susanna R. Keller, Thurl E. Harris, Douglas A. Bayliss, Norbert Leitinger
Publikováno v:
Molecular Metabolism, Vol 4, Iss 9, Pp 610-618 (2015)
Objective: Defective glucose uptake in adipocytes leads to impaired metabolic homeostasis and insulin resistance, hallmarks of type 2 diabetes. Extracellular ATP-derived nucleotides and nucleosides are important regulators of adipocyte function, but
Externí odkaz:
https://doaj.org/article/9b68597c47644aa7ac673be018d95003
Autor:
Hung-Jen Tang, Chih-Cheng Lai, Chi-Chung Chen, Chun-Cheng Zhang, Tzu-Chieh Weng, Wen-Liang Yu, Hung-Jui Chen, Yu-Hsin Chiu, Wen-Chien Ko, Yin-Ching Chuang
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The empirical combination of both a beta-lactam and glycopeptide to counter potential staphylococcal pathogens may improve the clinical outcomes for cases of Staphylococcus aureus bacteremia. We reported comparative in vitro studies of combination ef
Externí odkaz:
https://doaj.org/article/e5145037b2fa46f6a081e01c265d334d