Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Yu‐Sun Chang"'
Autor:
Yi‐Chan Lee, Li‐Yu Lee, Yenlin Huang, Huang‐Kai Kao, Ya‐Ting Chang, Shao‐Yu Hung, Chuieng‐Yi Lu, Yu‐Sun Chang, Jau‐Song Yu, Kai‐Ping Chang
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 8, Iss 6, Pp 1547-1556 (2023)
Abstract Objectives This study aimed to investigate the association between salivary matrix metalloproteinase‐1 (MMP‐1) and clinicopathological parameters of oral cavity squamous cell carcinoma (OSCC) and compare the prognostic efficacy of saliva
Externí odkaz:
https://doaj.org/article/37a98db104df46c6972d2329398a7fbf
Autor:
Hsin-Pai Li, Chen-Yang Huang, Kar-Wai Lui, Yin-Kai Chao, Chun-Nan Yeh, Li-Yu Lee, Yenlin Huang, Tung-Liang Lin, Yung-Chia Kuo, Mei-Yuan Huang, Hsien-Chi Fan, An-Chi Lin, Chia-Hsun Hsieh, Kai-Ping Chang, Chien-Yu Lin, Hung-Ming Wang, Mei Chao, Jai-Shin Liu, Yu-Sun Chang, Cheng-Lung Hsu
Publikováno v:
Translational Oncology, Vol 38, Iss , Pp 101785- (2023)
Background: Nasopharyngeal carcinoma (NPC) is associated with Epstein–Barr virus (EBV) infection. To test preclinical NPC drugs, we established two patient-derived xenograft (PDX) mouse models, EBV-positive PDX-B13 and EBV-negative PDX-Li41, for dr
Externí odkaz:
https://doaj.org/article/f7eab78612ce476a82caf328ba37a37e
Autor:
Chia-Chun Chen, Pi-Yueh Chang, Yu-Sun Chang, Jeng-Fu You, Err-Cheng Chan, Jinn-Shiun Chen, Wen-Sy Tsai, Yen-Lin Huang, Chung-Wei Fan, Hung-Chih Hsu, Jy-Ming Chiang
Publikováno v:
Biomedical Journal, Vol 46, Iss 1, Pp 144-153 (2023)
Background: Colorectal cancer (CRC) is still among the most lethal and prevalent malignancies in the world. Despite continuous efforts, the diagnosis and prognosis of CRC have never been satisfying, especially the non-invasive assays. Methods: Our st
Externí odkaz:
https://doaj.org/article/a2918836db8a4e7ba589b338948d4d2f
Publikováno v:
Diagnostics, Vol 13, Iss 13, p 2270 (2023)
Accumulative evidence suggests metabolic disorders correlate with prostate cancer. Metabolic profiling of urine allows the measurement of numerous metabolites simultaneously. This study set up a metabolomic platform consisting of UPLC-FTMS and UPLC-i
Externí odkaz:
https://doaj.org/article/6a7ef9e1a787441f9723ef4348f38f36
Autor:
Wei-Chen Yen, Ian Yi-Feng Chang, Kai‐Ping Chang, Chun‐Nan Ouyang, Chiao-Rou Liu, Ting-Lin Tsai, Yi-Cheng Zhang, Chun-I Wang, Ya-Hui Wang, Alice L. Yu, Hsuan Liu, Chih-Ching Wu, Yu-Sun Chang, Jau-Song Yu, Chia-Yu Yang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundOral cavity squamous cell carcinoma (OSCC) is an aggressive malignant tumor with high recurrence and poor prognosis in the advanced stage. Patient-derived xenografts (PDXs) serve as powerful preclinical platforms for drug testing and precis
Externí odkaz:
https://doaj.org/article/e4955367bb0648198150020a11e81645
Autor:
An‐Ko Chung, Chun‐Nan OuYang, Hsuan Liu, Mei Chao, Ji‐Dung Luo, Cheng‐Yang Lee, Yen‐Jung Lu, I‐Che Chung, Lih‐Chyang Chen, Shao‐Min Wu, Ngan‐Ming Tsang, Kai‐Ping Chang, Cheng‐Lung Hsu, Hsin‐Pai Li, Yu‐Sun Chang
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 5116-5127 (2019)
Abstract Approximately, 25% of nasopharyngeal carcinoma (NPC) patients develop recurrent disease. NPC may involve relatively few genomic alterations compared to other cancers due to its association with Epstein‐Barr virus (EBV). We envisioned that
Externí odkaz:
https://doaj.org/article/f8ef00ee3b1f461d9a6f56fe509e7a7e
Autor:
Pei-Chun Fan, Chia-Chun Chen, Chen-Ching Peng, Chih-Hsiang Chang, Chia-Hung Yang, Chi Yang, Lichieh Julie Chu, Yung-Chang Chen, Chih-Wei Yang, Yu-Sun Chang, Pao-Hsien Chu
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Acute kidney injury (AKI) is a common complication of acute myocardial infarction (AMI), and is associated with adverse outcomes. The study aimed to identify a miRNA signature for the early diagnosis of post-AMI AKI. Methods A tot
Externí odkaz:
https://doaj.org/article/07070de4bda24acdb78859c0813546e5
Autor:
Shu-Chen Liu, Tien Hsu, Yu-Sun Chang, An-Ko Chung, Shih Sheng Jiang, Chun-Nan OuYang, Chiou-Hwa Yuh, Chuen Hsueh, Ya-Ping Liu, Ngan-Ming Tsang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Molecular pathways regulating nasopharyngeal carcinoma (NPC) metastasis are unclear. Here they report higher levels of cytoplasmic leukemia inhibitory factor (cLIF) and LIF receptor (LIFR) to correlate with higher metastasis in NPC patients, and show
Externí odkaz:
https://doaj.org/article/5859dcee62b843f5bc95e474b541df8d
Autor:
Cheng-Lung Hsu, Kar-Wai Lui, Lang-Ming Chi, Yung-Chia Kuo, Yin-Kai Chao, Chun-Nan Yeh, Li-Yu Lee, Yenlin Huang, Tung-Liang Lin, Mei-Yuan Huang, Yi-Ru Lai, Yuan-Ming Yeh, Hsien-Chi Fan, An-Chi Lin, Yen-Jung Lu, Chia-Hsun Hsieh, Kai-Ping Chang, Ngan-Ming Tsang, Hung-Ming Wang, Alex Y. Chang, Yu-Sun Chang, Hsin-Pai Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-15 (2018)
Abstract Background Patient-derived xenograft (PDX) tumor model has become a new approach in identifying druggable tumor mutations, screening and evaluating personalized cancer drugs based on the mutated targets. Methods We established five nasophary
Externí odkaz:
https://doaj.org/article/dff05e3ff1904297b33a2ee23b7ed33c
Autor:
Hsin-Pai Li, Chen-Ching Peng, Chih-Ching Wu, Chien-Hsun Chen, Meng-Jhe Shih, Mei-Yuan Huang, Yi-Ru Lai, Yung-Li Chen, Ting-Wen Chen, Petrus Tang, Yu-Sun Chang, Kai-Ping Chang, Cheng-Lung Hsu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-16 (2018)
Abstract Background Aberrant hypermethylation of cellular genes is a common phenomenon to inactivate genes and promote tumorigenesis in nasopharyngeal carcinoma (NPC). Methods Methyl binding domain (MBD)-ChIP sequencing of NPC cells, microarray data
Externí odkaz:
https://doaj.org/article/ecce2e592b5540aa8d42367f5e147652