Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Yu‐Dong Zhou"'
Autor:
Rahim Ullah, Chuqing Xue, Senjie Wang, Zhewen Qin, Naveed Rauf, Shumin Zhan, Naimat Ullah Khan, Yi Shen, Yu-Dong Zhou, Junfen Fu
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background/Objectives Childhood obesity, particularly in girls, is linked to early puberty onset, heightening risks for adult-onset diseases. Addressing childhood obesity and precocious puberty is vital to mitigate societal burdens. Despite
Externí odkaz:
https://doaj.org/article/141ab49aa3a24cc9814e2a78d259832c
Autor:
Mika B. Jekabsons, Mollie Merrell, Anna G. Skubiz, Noah Thornton, Sandra Milasta, Douglas Green, Taosheng Chen, Yan-Hong Wang, Bharathi Avula, Ikhlas A. Khan, Yu-Dong Zhou
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-24 (2023)
Abstract Gene expression signatures associated with breast cancer metastases suggest that metabolic re-wiring is important for metastatic growth in lungs, bones, and other organs. However, since pathway fluxes depend on additional factors such as ATP
Externí odkaz:
https://doaj.org/article/7e752c0384814035bfa0d6530ec190eb
Autor:
Jinmei Jin, Yaping Wu, Zeng Zhao, Ye Wu, Yu-dong Zhou, Sanhong Liu, Qingyan Sun, Guizhu Yang, Jiayi Lin, Dale G. Nagle, Jiangjiang Qin, Zhiyuan Zhang, Hong-zhuan Chen, Weidong Zhang, Shuyang Sun, Xin Luan
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
The aberrant activation of STAT3 is associated with the etiology and progression in a variety of malignant epithelial-derived tumors, including head and neck squamous cell carcinoma (HNSCC) and colorectal cancer (CRC). Due to the lack of an enzymatic
Externí odkaz:
https://doaj.org/article/655ea3dd69dc4952b87fdc61cbdca2ff
Autor:
Yang He, Mengdi Wei, Yan Wu, Huaping Qin, Weinan Li, Xiaolin Ma, Jingjing Cheng, Jinshuai Ren, Ye Shen, Zhong Chen, Binggui Sun, Fu-De Huang, Yi Shen, Yu-Dong Zhou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
The underlying mechanism of amyloid β (Aβ) oligomer-induced aberrant neurotransmitter release remains unclear. Here, authors show that the release probability at the synapse between the Schaffer collateral and CA1 pyramidal neurons is significantly
Externí odkaz:
https://doaj.org/article/55e5dfe1d82d42c0af364801b3a94fc4
Autor:
Ting Fang, Yi-Xin Jiang, Long Chen, Ling Huang, Xin-Hui Tian, Yu-Dong Zhou, Dale G. Nagle, Dan-Dan Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Coix Seed Oil (CSO) possesses a wide range of pharmacological activities. Kanglaite Injection, a commercial product of CSO, has been used clinically as an anticancer drug in China for decades. However, its molecular mechanisms on triple-negative brea
Externí odkaz:
https://doaj.org/article/cedceb6614d74b25b3d4c9d878fb64f9
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Puberty generally occurs when an individual has stored a sufficient amount of energy. Previous reports have shown that postnatal overfeeding, induced by a small litter size or maternal high fat diet (HFD) feeding during gestation and lactation increa
Externí odkaz:
https://doaj.org/article/799c735616c64054acff01e05a6115bb
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Foraging food in a novel environment is essential for survival. Animals coordinate the complex motivated states and decide whether to initiate feeding or escape from unfamiliar scenes. Neurons in the paraventricular thalamic nucleus (PVT) receive mul
Externí odkaz:
https://doaj.org/article/cfc4b1f65cea496685b667aaa62cf521
Autor:
Juan Chen, Yang He, Yan Wu, Hang Zhou, Li-Da Su, Wei-Nan Li, Richard W. Olsen, Jing Liang, Yu-Dong Zhou, Yi Shen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Alcohol (ethanol, EtOH) is one of the most widely abused drugs with profound effects on brain function and behavior. GABAA receptors (GABAARs) are one of the major targets for EtOH in the brain. Temporary plastic changes in GABAARs after withdrawal f
Externí odkaz:
https://doaj.org/article/9a93d31a3f3741718195b55b37024260
Autor:
J. Brian Morgan, Yang Liu, Veena Coothankandaswamy, Fakhri Mahdi, Mika B. Jekabsons, William H. Gerwick, Frederick A. Valeriote, Yu-Dong Zhou, Dale G. Nagle
Publikováno v:
Marine Drugs, Vol 13, Iss 3, Pp 1552-1568 (2015)
The biologically active lipopeptide kalkitoxin was previously isolated from the marine cyanobacterium Moorea producens (Lyngbya majuscula). Kalkitoxin exhibited N-methyl-d-aspartate (NMDA)-mediated neurotoxicity and acted as an inhibitory ligand for
Externí odkaz:
https://doaj.org/article/81c9cdfe74804be6b9ba6bfe82baaec1
Autor:
Yu-Dong Zhou, Jun Li, Lin Du, Fakhri Mahdi, Thuy P. Le, Wei-Lun Chen, Steven M. Swanson, Kounosuke Watabe, Dale G. Nagle
Publikováno v:
Marine Drugs, Vol 16, Iss 11, p 442 (2018)
Breast tumors reprogram their cellular metabolism, nutrient uptake, and utilization-associated biochemical processes. These processes become further transformed as genetically predisposed metastatic breast tumor cells colonize specific organs. Breast
Externí odkaz:
https://doaj.org/article/7f84aebf78ef426cb74e0e25fc4ec216