NAT10 Promotes Prostate Cancer Growth and Metastasis by Acetylating mRNAs of HMGA1 and KRT8

Autor: Kang‐Jing Li, Yaying Hong, Yu‐Zhong Yu, Zhiyue Xie, Dao‐Jun Lv, Chong Wang, Tao Xie, Hong Chen, Zhe‐Sheng Chen, Jianwen Zeng, Shan‐Chao Zhao

Publikováno v: Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)

Abstract N4‐acetylcytidine (ac4C) is essential for the development and migration of tumor cells. According to earlier research, N‐acetyltransferase 10 (NAT10) can increase messenger RNAs (mRNAs) stability by catalyzing the synthesis of ac4C. Howe

Externí odkaz: https://doaj.org/article/cac7cd653f3b44c9b69f645b1ca0cbca

Correction: CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling

Autor: Tao Xie, Du-jiang Fu, Zhi-min Li, Dao-jun Lv, Xian-Lu Song, Yu-zhong Yu, Chong Wang, Kang-jin Li, Baoqian Zhai, Jiacheng Wu, Ning-Han Feng, Shan-Chao Zhao

Publikováno v: Molecular Cancer, Vol 22, Iss 1, Pp 1-6 (2023)

Externí odkaz: https://doaj.org/article/1ea41e44fa144218bbc8318a7d009b72

Identification of UAP1L1 as a critical factor for prostate cancer and underlying molecular mechanism in tumorigenicity

Autor: Xing-cheng Wu, Yu-zhong Yu, Yu-zhi Zuo, Xian-Lu Song, Zhi-en Zhou, Yu Xiao, Dao-sheng Luo, Wei-gang Yan, Shan-Chao Zhao

Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)

Abstract Background Prostate cancer is the second most common cancer in men, and some new target genes are needed to predict the risk of prostate cancer progression and the treatment. Methods In this study, the effects of UAP1L1 (UAP1-like-1) on pros

Externí odkaz: https://doaj.org/article/7b71c557da214f2990ff28bd68859a2b

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A novel palmitic acid hydroxy stearic acid (5‐PAHSA) plays a neuroprotective role by inhibiting phosphorylation of the m‐TOR‐ULK1 pathway and regulating autophagy.

Autor: Wang, Jian‐tao¹ (AUTHOR), Yu, Zhong‐yu¹ (AUTHOR), Tao, Ying‐hong² (AUTHOR), Liu, Ying‐chao³ (AUTHOR), Wang, Yan‐mei¹ (AUTHOR), Guo, Qi‐lin⁴ (AUTHOR), Xue, Jian‐zhong⁵ (AUTHOR), Wen, Xiao‐hong⁴ (AUTHOR), Zhang, Qian⁴ (AUTHOR), Xu, Xiao‐die⁴ (AUTHOR), He, Cheng‐feng⁴ (AUTHOR), Xue, Wen‐jiao⁴ (AUTHOR), Guo, Jing‐chun⁴ (AUTHOR) jingchunguo@shmu.edu.cn, Zhou, Hou‐guang¹ (AUTHOR) jingchunguo@shmu.edu.cn

Publikováno v: CNS Neuroscience & Therapeutics. Apr2021, Vol. 27 Issue 4, p484-496. 13p.