Bismuth-based mesoporous nanoball carrying sorafenib for synergistic photothermal and molecularly-targeted therapy in an orthotopic hepatocellular carcinoma xenograft mouse model.

Autor: Zhang GC; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Song K; School of Materials and Chemistry, Institute of Bismuth Science, Shanghai Collaborative Innovation Center of Energy Therapy for Tumors, University of Shanghai for Science and Technology, Shanghai 200093, China., Wang XF; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., He Z; School of Materials and Chemistry, Institute of Bismuth Science, Shanghai Collaborative Innovation Center of Energy Therapy for Tumors, University of Shanghai for Science and Technology, Shanghai 200093, China., Du J; School of Materials and Chemistry, Institute of Bismuth Science, Shanghai Collaborative Innovation Center of Energy Therapy for Tumors, University of Shanghai for Science and Technology, Shanghai 200093, China., Sun JL; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Xu RC; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Liu ZY; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Wang F; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Qi ZR; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Yu XN; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Miao Y; School of Materials and Chemistry, Institute of Bismuth Science, Shanghai Collaborative Innovation Center of Energy Therapy for Tumors, University of Shanghai for Science and Technology, Shanghai 200093, China., Dong L; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Weng SQ; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China., Shen XZ; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China; Key Laboratory of Medical Molecular Virology, Shanghai Medical College of Fudan University, 138 Yixueyuan Rd., Shanghai 200032, China., Liu TT; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China; Department of Gastroenterology and Hepatology, Shanghai Geriatric Medical Center, Shanghai, China. Electronic address: liu.taotao@zs-hospital.sh.cn., Li Y; School of Materials and Chemistry, Institute of Bismuth Science, Shanghai Collaborative Innovation Center of Energy Therapy for Tumors, University of Shanghai for Science and Technology, Shanghai 200093, China. Electronic address: yhli@usst.edu.cn., Zhu JM; Department of Gastroenterology and Hepatology and Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, 180 Fenglin Rd., Shanghai 200032, China. Electronic address: zhu.jimin@zs-hospital.sh.cn.

Publikováno v: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2024 Oct 01; Vol. 245, pp. 114279. Date of Electronic Publication: 2024 Oct 01.

UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma

Autor: Liu LL, Zhu JM, Yu XN, Zhu HR, Shi X, Bilegsaikhan E, Guo HY, Wu J, Shen XZ

Publikováno v: Cancer Management and Research, Vol Volume 11, Pp 8359-8370 (2019)

Li-Li Liu,1,2,* Ji-Min Zhu,1,2,* Xiang-Nan Yu,1,2 Hai-Rong Zhu,1,2 Xuan Shi,1,2 Enkhnaran Bilegsaikhan,1,2 Hong-Ying Guo,1,2 Jian Wu,1–3 Xi-Zhong Shen1–3 1Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shangh

Externí odkaz: https://doaj.org/article/eceb21c9db644738b68188e818c9fbe9

Multi-Omics profiling identifies aldehyde dehydrogenase 2 as a critical mediator in the crosstalk between Treg-mediated immunosuppression microenvironment and hepatocellular carcinoma.

Autor: Liu ZY; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Lin XH; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Guo HY; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Shi X; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Zhang DY; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Sun JL; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Zhang GC; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Xu RC; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Wang F; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Yu XN; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Wang D; Department of Gastroenterology, Shigatse People's Hospital, Shigatse, Tibet 857000, China., Weng SQ; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Shen XZ; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China.; Key Laboratory of Medical Molecular Virology, Shanghai Medical College of Fudan University, Shanghai 200030, China., Liu TT; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Dong L; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China., Zhu JM; Department of Gastroenterology and Hepatology, Zhongshan Hospital of Fudan University, Shanghai 200030, China.; Shanghai Institute of Liver Diseases, Shanghai 200030, China.

Publikováno v: International journal of biological sciences [Int J Biol Sci] 2024 May 05; Vol. 20 (7), pp. 2763-2778. Date of Electronic Publication: 2024 May 05 (Print Publication: 2024).

Increased expression of autophagy-related gene 5 indicates poor prognosis in patients with hepatocellular carcinoma.

Autor: Guo HY; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Severe Hepatitis, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China., Yu XN; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Zhang GC; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Yin J; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Dong L; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Liu TT; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Qian ZP; Department of Severe Hepatitis, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China., Zhu JM; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Shen XZ; Department of Gastroenterology and Hepatology, Shanghai Institute of Liver Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.

Publikováno v: Journal of digestive diseases [J Dig Dis] 2023 Jun-Jul; Vol. 24 (6-7), pp. 399-407.

Preclinical Investigations on Anti-fibrotic Potential of Long-Term Oral Therapy of Sodium Astragalosidate in Animal Models of Cardiac and Renal Fibrosis.

Autor: Chen XY; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China.; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China., Wang TT; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China.; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China., Shen Q; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China.; Collaborative Innovation Center of Seafood Deep Processing, Zhejiang Province Joint Key Laboratory of Aquatic Products Processing, Institute of Seafood, Zhejiang Gongshang University, Hangzhou 310012, China., Ma H; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China., Li ZH; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China., Yu XN; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China., Huang XF; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China., Qing LS; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China., Luo P; State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Pharmacy, Macau University of Science and Technology, Macau 999078, China.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2024 Jan 12; Vol. 7 (2), pp. 421-431. Date of Electronic Publication: 2024 Jan 12 (Print Publication: 2024).