STZ-induced gestational diabetes exposure alters PTEN/AKT/mTOR-mediated autophagy signaling pathway leading to increase the risk of neonatal hypoxic-ischemic encephalopathy

Autor: Gong, Lei, Jiang, Siyi, Tian, Jia, Li, Yong, Yu, Wansu, Zhang, Lubo, Xiao, Daliao

Publikováno v: In Reproductive Toxicology January 2024 123

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HSPA12A acts as a scaffolding protein to inhibit cardiac fibroblast activation and cardiac fibrosis.

Autor: Mao Q; Department of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Zhang X; Department of Geriatrics, Jiangsu Provincial Key Laboratory of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Yang J; Department of Geriatrics, Jiangsu Provincial Key Laboratory of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Kong Q; Department of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Cheng H; Department of Anesthesiology, The First Affiliated Hospital with Wannan Medical College, Wuhu, China., Yu W; Department of Geriatrics, Jiangsu Provincial Key Laboratory of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Cao X; Department of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Li Y; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, China., Li C; Departments of Surgery, East Tennessee State University, Johnson City, TN 37614, USA., Liu L; Department of Geriatrics, Jiangsu Provincial Key Laboratory of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, China., Ding Z; Department of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: zhengnianding@njmu.edu.cn.

Publikováno v: Journal of advanced research [J Adv Res] 2024 Jan 14. Date of Electronic Publication: 2024 Jan 14.