Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Yu, Chia Chen"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) describes a group of progressive lung diseases causing breathing difficulties. While COPD development typically involves a complex interplay between genetic and environmental factors, g
Externí odkaz:
https://doaj.org/article/4dd87f0c58ce4d90937b41a66aa2f5e6
Autor:
Wen-Der Lin, Chia-Hao Chang, Jhih-Kai Pan, Forn-Chia Lin, Yu-Chia Chen, Ya-Jyun Chen, Po-Shun Wang, Wei-Qiao Hong, Sheng-Yuan Chen, Cheng-Han Lin, Yao-Lung Kuo, Wei-Pang Chung, Hui-Chuan Cheng, Michael Hsiao, Chia-Ning Yang, Pei-Jung Lu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-15 (2024)
Abstract Breast cancer (BC) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. The 5-year survival rate is over 90% in BC patients, but once BC cells metastasis into distal organs, it is dramatically decreasi
Externí odkaz:
https://doaj.org/article/0e72ccd055a6489e86d1063eb6f30659
Publikováno v:
Biomedical Journal, Vol 47, Iss 6, Pp 100725- (2024)
Background: Tourette syndrome (TS) is a neurodevelopmental disorder characterized by motor and vocal tics. Several susceptibility loci associated with TS have been identified previously in populations of European descent using genome-wide association
Externí odkaz:
https://doaj.org/article/b24a391a6f2a4959877cf9e736c34804
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Objective To identify new genetic variants associated with SLE in Taiwan and establish polygenic risk score (PRS) models to improve the early diagnostic accuracy of SLE.Methods The study enrolled 2429 patients with SLE and 48 580 controls from China
Externí odkaz:
https://doaj.org/article/1d24f5e065f249ef95649fc0be2c978d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
IntroductionAngiopoietin 1 (angpt1) is essential for angiogenesis. However, its role in neurogenesis is largely undiscovered. This study aimed to identify the role of angpt1 in brain development, the mode of action of angpt1, and its prime targets in
Externí odkaz:
https://doaj.org/article/e243d479abf14f628418ea9fca5217bd
Autor:
Yu-Chuen Huang, Wen-Ling Liao, Hui-Ju Lin, Yu-Te Huang, Ya-Wen Chang, Ting-Yuan Liu, Yu-Chia Chen, Angel L. Weng, Fuu-Jen Tsai
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3230 (2024)
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly worldwide. The prevalence and phenotypes of AMD differ among populations, including between people in Taiwan and other regions. We performed a genome-wide associa
Externí odkaz:
https://doaj.org/article/958bb8ba80464c528cbdedd32469ea54
Autor:
Jan-Gowth Chang, Siang-Jyun Tu, Chung-Ming Huang, Yu-Chia Chen, Hui-Shan Chiang, Ya-Ting Lee, Ju-Chen Yen, Chia-Li Lin, Chin-Chun Chung, Ta-Chih Liu, Ya-Sian Chang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Cell subpopulations in the blood and joint fluid of patients with gout are poorly understood. Single-cell RNA sequencing and bioinformatic tools were used to identify cell subsets and their gene signatures in blood and synovial fluid (SF) ce
Externí odkaz:
https://doaj.org/article/648764da88ec49eb81d17b56f7d30f19
Autor:
Yu-Chia Chen
Publikováno v:
International Journal of Child Development and Mental Health, Vol 10, Iss 1, Pp 20-30 (2022)
Attention Deficit and Hyperactivity Disorder (ADHD) is a disease that cannot be overcome only by clinical diagnosis and treatment. It is a complex problem that affects both society and medicine. This article first analyzes the societal causes and dis
Externí odkaz:
https://doaj.org/article/5e47bb503f3049f382c5b56d231265fa
Autor:
Ya-Sian Chang, Chien-Yu Lin, Ting-Yuan Liu, Chung-Ming Huang, Chin-Chun Chung, Yu-Chia Chen, Fuu-Jen Tsai, Jan-Gowth Chang, Shun-Jen Chang
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-11 (2022)
Abstract Background Gout is a highly hereditary disease, but not all those carrying well-known risk variants have developing gout attack even in hyperuricemia status. We performed a genome-wide association study (GWAS) and polygenic risk score (PRS)
Externí odkaz:
https://doaj.org/article/39446ed8b9a54b87973696c8a4650ad2
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