Déséquilibre de liaison et cartographie de QTL en population sélectionnée

Autor: Ytournel, Florence

Par définition le déséquilibre de liaison (Linkage Disequilibrium, LD) décrit les associations préférentielles entre allèles de deux locus. Ce concept est devenu un outil indispensable pour la cartographie fine de locus quantitatifs (QTL), par

Externí odkaz: http://pastel.archives-ouvertes.fr/pastel-00003789
http://pastel.archives-ouvertes.fr/docs/00/50/08/45/PDF/Manuscrit_YTOURNEL.pdf

Does probabilistic modelling of linkage disequilibrium evolution improve the accuracy of QTL location in animal pedigree?

Autor: Estivals Delphine, Ytournel Florence, Druet Tom, Gilbert Hélène, Legarra Andrés, Dejean Sébastien, Cierco-Ayrolles Christine, Oumouhou Naïma, Mangin Brigitte

Publikováno v: Genetics Selection Evolution, Vol 42, Iss 1, p 38 (2010)

Abstract Background Since 2001, the use of more and more dense maps has made researchers aware that combining linkage and linkage disequilibrium enhances the feasibility of fine-mapping genes of interest. So, various method types have been derived to

Externí odkaz: https://doaj.org/article/f2e0df66306e4bb1adeecddb2c5b7a93

LDSO : A progroam to simulate pedigrees and molecular information under various evolutionary forces

Autor: Ytournel, Florence, Teyssedre, Simon, Roldan, Dana, Erbe, M., Simianer, H., Boichard, Didier, Gilbert, Hélène, Druet, Tom, Legarra, Andres

Publikováno v: Journal of Animal Breeding and Genetics
Journal of Animal Breeding and Genetics, Wiley, 2012, 129 (5), pp.417-421. ⟨10.1111/j.1439-0388.2011.00986.x⟩

Simulations are a major tool to evaluate new statistical methods and optimize experimental designs in the genomic era. However, this can only be achieved when the simulations are close enough to reality, as well as diverse enough to be realistic. For

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d4bc79847de62c8f455cc1544edb67c5
https://hal.archives-ouvertes.fr/hal-01000612

Comment affiner la localisation d'un QTL ?

Autor: Ytournel, Florence, Gilbert, Hélène, Boichard, Didier

Publikováno v: Productions animales
Productions animales, Institut National de la Recherche Agronomique, 2008, 21 (2), pp.147-158

National audience; Many methods are offered to finely map loci implicated in the variability of quantitative traits (Quantitative trait loci or QTL). The diversity of these methods can be explained notably by the differences that exist between specie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2592::949ca93ae45d0f0507ae0ef64c158676
https://hal.inrae.fr/hal-02665716/file/2008_ytournel_prod_anim_1.pdf

Structure of linkage disequilibrium and length of IBD segments in simulated populations

Autor: Ytournel, Florence, Gilbert, Hélène, Druet, Tom, Boichard, Didier

Publikováno v: 8th World Congress on Genetics Applied to Livestock Production, Belo Horizonte, Brazil, INC, 2006
8th World Congress on Genetics Applied to Livestock Production, Belo Horizonte
8th World Congress on Genetics Applied to Livestock Production, Belo Horizonte, 2006, Brazil, pp.Inconnu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::da6283da889ecd510852f40c52a18327
http://prodinra.inra.fr/record/4906