Anti-Cancer and Radio-Sensitizing Properties of New Bimetallic (N-Heterocyclic Carbene)-Amine-Pt(II) Complexes

Autor: Tao Jia, Oumar Diane, Deepanjan Ghosh, Myriem Skander, Gaelle Fontaine, Pascal Retailleau, Joël Poupon, Jérôme Bignon, Ytabelle Maga Moulai Siasia, Vincent Servajean, Nathalie Hue, Jean-François Betzer, Angela Marinetti, Sophie Bombard

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2023, 66 (10), pp.6836-6848. ⟨10.1021/acs.jmedchem.3c00267⟩

International audience; Bioactive NHC-transition metal complexes have shown promise as anti-cancer agents, but their potential use as radiosensitizers has been neglected so far. We disclose here a new series of bimetallic platinum(II) complexes displ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5350758825484445abd2a2d5b6b0ba
https://doi.org/10.1021/acs.jmedchem.3c00267