Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yrr Morch"'
Autor:
Astrid Hyldbakk, Yrr Mørch, Sofie Snipstad, Andreas K.O. Åslund, Geir Klinkenberg, Vu To Nakstad, Ane-Marit Wågbø, Ruth Schmid, Peter P. Molesworth
Publikováno v:
International Journal of Pharmaceutics: X, Vol 4, Iss , Pp 100124- (2022)
Poly (alkyl cyanoacrylate) (PACA) polymeric nanoparticles (NPs) are promising drug carriers in drug delivery. However, the selection of commercially available alkyl cyanoacrylate (ACA) monomers is limited, because most monomers were designed for use
Externí odkaz:
https://doaj.org/article/25e19769b35c47c6b4460205bdec8409
Autor:
Karianne Giller Fleten, Astrid Hyldbakk, Caroline Einen, Sopisa Benjakul, Berit Løkensgard Strand, Catharina de Lange Davies, Ýrr Mørch, Kjersti Flatmark
Publikováno v:
Marine Drugs, Vol 20, Iss 12, p 744 (2022)
Alginate hydrogels have been broadly investigated for use in medical applications due to their biocompatibility and the possibility to encapsulate cells, proteins, and drugs. In the treatment of peritoneal metastasis, rapid drug clearance from the pe
Externí odkaz:
https://doaj.org/article/a16079ac8abc4d238536f173635e1d74
Autor:
Abhilash D. Pandya, Tore-Geir Iversen, Siver Moestue, Maria T. Grinde, Ýrr Mørch, Sofie Snipstad, Andreas K. O. Åslund, Geir F. Øy, Wanja Kildal, Olav Engebråten, Kirsten Sandvig, Tore Skotland, Gunhild M. Mælandsmo
Publikováno v:
Nanomaterials, Vol 11, Iss 5, p 1140 (2021)
We have investigated the biodistribution and tumor macrophage infiltration after intravenous injection of the poly(alkyl cyanoacrylate) nanoparticles (NPs): PEBCA (poly(2-ethyl-butyl cyanoacrylate), PBCA (poly(n-butyl cyanoacrylate), and POCA (poly(o
Externí odkaz:
https://doaj.org/article/8c550cf215934d1a9f834853b4184879
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 640 (2021)
Therapeutic agents can benefit from encapsulation in nanoparticles, due to improved pharmacokinetics and biodistribution, protection from degradation, increased cellular uptake and sustained release. Microbubbles in combination with ultrasound have b
Externí odkaz:
https://doaj.org/article/74f96de38ab64b08b368df2f3927d2e8
Autor:
Einar Sulheim, Tore-Geir Iversen, Vu To Nakstad, Geir Klinkenberg, Håvard Sletta, Ruth Schmid, Anne Rein Hatletveit, Ane Marit Wågbø, Anders Sundan, Tore Skotland, Kirsten Sandvig, Ýrr Mørch
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2454 (2017)
Although nanotoxicology has become a large research field, assessment of cytotoxicity is often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and should, preferentially, be evaluated in several cell lines with dif
Externí odkaz:
https://doaj.org/article/202d45f8c0644fa68206a5cb1e219976
Publikováno v:
Drug Delivery and Translational Research
The development of drug nanocarriers based on polymeric, lipid and ceramic biomaterials has been paving the way to precision medicine, where the delivery of poorly soluble active compounds and personalized doses are made possible. However, the nano-s
Autor:
Karianne Giller Fleten, Christin Lund-Andersen, Stein Waagene, Torveig Weum Abrahamsen, Yrr Mørch, Kjetil Boye, Annette Torgunrud, Kjersti Flatmark
Publikováno v:
Translational Oncology, Vol 13, Iss 8, Pp 100793- (2020)
Mucinous peritoneal metastases (PM) generally respond poorly to systemic treatment, and there is a clear unmet need for new treatment strategies to improve survival and quality of life for patients with PM. In this work, the growth inhibitory effect
Externí odkaz:
https://doaj.org/article/c664c599f0e54faea0f890aa18ffc530
Autor:
Habib Baghirov, Sofie Snipstad, Einar Sulheim, Sigrid Berg, Rune Hansen, Frits Thorsen, Yrr Mørch, Catharina de Lange Davies, Andreas K O Åslund
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191102 (2018)
The treatment of brain diseases is hindered by the blood-brain barrier (BBB) preventing most drugs from entering the brain. Focused ultrasound (FUS) with microbubbles can open the BBB safely and reversibly. Systemic drug injection might induce toxici
Externí odkaz:
https://doaj.org/article/46b56ab6ef9b467a8cea41c9f0493381