Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Multi-omics links IL-6 trans-signalling with neutrophil extracellular trap formation and Haemophilus infection in COPD.

Autor: Winslow S; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Odqvist L; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Diver S; Dept of Respiratory Science, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, UK., Riise R; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Abdillahi S; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Wingren C; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Lindmark H; Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Wellner A; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Lundin S; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Yrlid L; Bioscience COPD/IPF, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ax E; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Krefting Research Centre, Institute of Medicine at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Djukanovic R; NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, University of Southampton, Southampton, UK., Sridhar S; Oncology Bioinformatics, Translational Science, Early Oncology, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Higham A; The University of Manchester Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust, Manchester, UK., Singh D; The University of Manchester Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust, Manchester, UK., Southworth T; The University of Manchester Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust, Manchester, UK., Brightling CE; Dept of Respiratory Science, Institute for Lung Health, NIHR Leicester Biomedical Research Centre, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, UK., Olsson HK; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Jevnikar Z; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden Zala.JevnikarRojnik@astrazeneca.com.

Publikováno v: The European respiratory journal [Eur Respir J] 2021 Oct 14; Vol. 58 (4). Date of Electronic Publication: 2021 Oct 14 (Print Publication: 2021).

Cholera toxin adjuvant promotes a balanced Th1/Th2/Th17 response independently of IL-12 and IL-17 by acting on Gsα in CD11b⁺ DCs.

Autor: Mattsson, J, Schön, K, Ekman, L, Fahlén-Yrlid, L, Yrlid, U, Lycke, N Y

Publikováno v: Mucosal Immunology (1933-0219); Jul2015, Vol. 8 Issue 4, p815-827, 13p

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus.

Autor: Odqvist L; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Jevnikar Z; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Riise R; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Öberg L; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Rhedin M; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Leonard D; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Yrlid L; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Jackson S; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Mattsson J; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Nanda S; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Cohen P; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Knebel A; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Arthur S; Division of Immunology and Cell Signaling, School of Life Sciences, University of Dundee, Dundee, UK., Thörn K; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Svenungsson E; Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden., Jönsen A; Skåne University Hospital, Department of Clinical Science Lund, Rheumatology, Lund University, Lund, Sweden., Gunnarsson I; Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden., Tandre K; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Alexsson A; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Kastbom A; Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linkoping, Sweden., Rantapää-Dahlqvist S; Department of Public Health and Clinical Medicine/Rheumatology, Umeå Universitet Medicinska fakulteten, Umea, Sweden., Eloranta ML; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Syvänen AC; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Bengtsson A; Skåne University Hospital, Department of Clinical Science Lund, Rheumatology, Lund University, Lund, Sweden., Johansson P; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Sandling JK; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Sjöwall C; Department of Rheumatology and Department of Clinical and Experimental Medicine, Linköping University, Linkoping, Sweden., Rönnblom L; Department of Medical Sciences, Science for Life Laboratories, Uppsala University, Uppsala, Sweden., Collins B; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden., Vaarala O; Research and Early Development, Respiratory, Inflammation and Autoimmune, BioPharmaceuticals R&D, AstraZeneca R&D Gothenburg, Mölndal, Sweden vaaralao@medimmune.com.; Respiratory, Inflammation and Autoimmunity Department, MedImmune LLC, Gaithersburg, Maryland, USA.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2019 Oct; Vol. 78 (10), pp. 1363-1370. Date of Electronic Publication: 2019 Jul 12.

Polymorphisms in the multidrug-resistance 1 gene related to glucocorticoid response in rheumatoid arthritis treatment.

Autor: Cuppen BV; Rheumatology and Clinical Immunology, University Medical Center Utrecht, F02.127, 3508 GA, Utrecht, The Netherlands. b.v.j.cuppen@umcutrecht.nl., Pardali K; Respiratory and Inflammation iMed, AstraZeneca, Pepparedsleden 1, 431 83, Mölndal, Sweden. katerina.pardali@astrazeneca.com., Kraan MC; Rheumatology and Clinical Immunology, University Medical Center Utrecht, F02.127, 3508 GA, Utrecht, The Netherlands.; Respiratory and Inflammation iMed, AstraZeneca, Pepparedsleden 1, 431 83, Mölndal, Sweden., Marijnissen AC; Rheumatology and Clinical Immunology, University Medical Center Utrecht, F02.127, 3508 GA, Utrecht, The Netherlands., Yrlid L; Respiratory and Inflammation iMed, AstraZeneca, Pepparedsleden 1, 431 83, Mölndal, Sweden., Olsson M; Respiratory and Inflammation iMed, AstraZeneca, Pepparedsleden 1, 431 83, Mölndal, Sweden., Bijlsma JW; Rheumatology and Clinical Immunology, University Medical Center Utrecht, F02.127, 3508 GA, Utrecht, The Netherlands., Lafeber FP; Rheumatology and Clinical Immunology, University Medical Center Utrecht, F02.127, 3508 GA, Utrecht, The Netherlands., Fritsch-Stork RD; Rheumatology and Clinical Immunology, University Medical Center Utrecht, F02.127, 3508 GA, Utrecht, The Netherlands.; 1st Medical Department and Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Hanusch Hospital, Vienna, Austria.; Sigmund Freud University, Vienna, Austria.

Publikováno v: Rheumatology international [Rheumatol Int] 2017 Apr; Vol. 37 (4), pp. 531-536. Date of Electronic Publication: 2017 Jan 28.