Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yram Foli"'
Autor:
Xingxing Wang, Marius Wollan, In-Jung Kim, Devon M. Chenette, Yuichi Sekine, Joshua R. Sanes, Yram Foli, Nicholas M. Tran, Stephen M. Strittmatter, Jane A. Lindborg, Kristin DeLuca, Ramakrishnan Kannan
Publikováno v:
Cell reports
SUMMARY Adult mammalian central nervous system (CNS) trauma interrupts neural networks and, because axonal regeneration is minimal, neurological deficits persist. Repair via axonal growth is limited by extracellular inhibitors and cell-autonomous fac
Autor:
S Selvaraj, Zongzhi Liu, Elijah Paintsil, Yiming Hu, G Wang, Yram Foli, Wing Lam, Qiongshi Lu, Min Li
Publikováno v:
HIV Medicine
Objectives We recently observed a decrease in deoxyribonucleotide (dNTP) pools in HIV-infected individuals on antiretroviral therapy (ART). Alterations in dNTPs result in mutations in mitochondrial DNA (mtDNA) in cell culture and animal models. There
Publikováno v:
Antimicrobial agents and chemotherapy. 61(8)
A case-control study of the effect of antiretroviral therapy (ART) on apoptosis pathway genes comprising 16 cases (HIV infected with mitochondrial toxicity) and 16 controls (HIV uninfected) was conducted. A total of 26 of 84 genes of the apoptosis pa
Autor:
Nana Y. Amakye, Min Li, Elijah Paintsil, Taline Monteiro Klein, Yram Foli, Lingeng Lu, Shanmugapriya Selvaraj
Publikováno v:
Journal of clinical pharmacology. 55(10)
Keywords: antiretroviral therapy; mitochondrial toxicity; telomere length; telomerase; immune activation
Autor:
Musie Ghebremichael, Wing Lam, Regina Edifor, Yung-Chi Cheng, Allison Langs-Barlow, Shanmugapriya Selvaraj, Min Li, Yram Foli, Lydia Barakat, Elizabeth Tubridy, Arit Ogbuagu, Elijah Paintsil
Publikováno v:
Clinical pharmacology and therapeutics
We hypothesized that competition between nucleotide reverse-transcriptase inhibitor triphosphate and endogenous deoxyribonucleotide triphosphate (dNTP) may lead to depletion of dNTP pools and mitochondrial dysfunction independent of polymerase-γ (po