Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yow Yong Tan"'
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1910 (2021)
Integrases of different retroviruses assemble as functional complexes with varying multimers of the protein. Retroviral integrases require a divalent metal cation to perform one-step transesterification catalysis. Tetrameric prototype foamy virus (PF
Externí odkaz:
https://doaj.org/article/50d6c6106d0c4d368abdd692035608cf
Autor:
Jiazi Tan, Yow-Yong Tan, Zhen-Kai Ngian, Suet-Yen Chong, Vinay Kumar Rao, Jiong-Wei Wang, Xianmin Zeng, Chin-Tong Ong
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109231- (2024)
Summary: ApoE regulates neurogenesis, although how it influences genetic programs remains elusive. Cortical neurons induced from isogenic control and ApoE−/− human neural stem cells (NSCs) recapitulated key transcriptomic signatures of in vivo co
Externí odkaz:
https://doaj.org/article/435dcf059a2749398cfe3bb525b64f9b
Autor:
Zhen-Kai Ngian, Yow-Yong Tan, Ching-Thong Choo, Wei-Qi Lin, Chao-Yong Leow, Shan-Jie Mah, Mitchell Kim-Peng Lai, Christopher Li-Hsian Chen, Chin-Tong Ong
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β plaques and Tau tangles in brain tissues. Recent studies indicate that aberrant splicing and increased level of intron retention is linked to AD pathogenesis. Bioinformatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799763856e292a87831fadc2c5ca751e
https://doi.org/10.1073/pnas.2204179119
https://doi.org/10.1073/pnas.2204179119
Autor:
Anne M. Gardner, Yow Yong Tan, Richard Fishel, Kristine E. Yoder, Nathan D. Jones, Ryan K. Messer, Gayan Senavirathne, Randi M. Kotlar, Anthony J. Rabe
Publikováno v:
The Journal of Biological Chemistry
Retroviral integrases must navigate host DNA packaged as chromatin during integration of the viral genome. Prototype foamy virus (PFV) integrase (IN) forms a tetramer bound to two viral DNA (vDNA) ends in a complex termed an intasome. PFV IN consists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0972a0bff672c3b59ec64ad9561804f
https://doi.org/10.1016/j.jbc.2021.100550
https://doi.org/10.1016/j.jbc.2021.100550
Autor:
Kotlar, Randi M.1, Jones, Nathan D.1,2, Senavirathne, Gayan1,2, Gardner, Anne M.1,2, Messer, Ryan K.1,2, Yow Yong Tan1,2, Rabe, Anthony J.1,2, Fishel, Richard1,2, Yoder, Kristine E.1,2 yoder.176@osu.edu
Publikováno v:
Journal of Biological Chemistry. Jan-Jun2021, Vol. 296, p1-14. 14p.