Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Yovanni Casablanca"'
Autor:
Collin A. Sitler, Chunqiao Tian, Chad A. Hamilton, Michael T. Richardson, John K. Chan, Daniel S. Kapp, Charles A. Leath, Yovanni Casablanca, Christina Washington, Nicole P. Chappell, Ann H. Klopp, Craig D. Shriver, Christopher M. Tarney, Nicholas W. Bateman, Thomas P. Conrads, George Larry Maxwell, Neil T. Phippen, Kathleen M. Darcy
Publikováno v:
Cancers, Vol 16, Iss 5, p 1071 (2024)
Purpose: To investigate IMT use and survival in real-world stage IVB cervical cancer patients outside randomized clinical trials. Methods: Patients diagnosed with stage IVB cervical cancer during 2013–2019 in the National Cancer Database and treate
Externí odkaz:
https://doaj.org/article/073012a1d2714c759e8039228d8c9a8c
Autor:
Nicholas W. Bateman, Christopher M. Tarney, Tamara Abulez, Anthony R. Soltis, Ming Zhou, Kelly Conrads, Tracy Litzi, Julie Oliver, Brian Hood, Paul Driggers, Coralie Viollet, Clifton Dalgard, Matthew Wilkerson, William Catherino, Chad A. Hamilton, Kathleen M. Darcy, Yovanni Casablanca, Ayman Al-Hendy, James Segars, Thomas P. Conrads, G. Larry Maxwell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Pathogenic mutations in fumarate hydratase (FH) drive hereditary leiomyomatosis and renal cell cancer (HLRCC) and increase the risk of developing uterine leiomyomas (ULMs). An integrated proteogenomic analysis of ULMs from HLRCC (n = 16; FH-
Externí odkaz:
https://doaj.org/article/c023cf0dac914100a5bb9c69090f4b69
Autor:
Nicholas W. Bateman, Christopher M. Tarney, Tamara S. Abulez, Brian L. Hood, Kelly A. Conrads, Ming Zhou, Anthony R. Soltis, Pang-Ning Teng, Amanda Jackson, Chunqiao Tian, Clifton L. Dalgard, Matthew D. Wilkerson, Michael D. Kessler, Zachary Goecker, Jeremy Loffredo, Craig D. Shriver, Hai Hu, Michele Cote, Glendon J. Parker, James Segars, Ayman Al-Hendy, John I. Risinger, Neil T. Phippen, Yovanni Casablanca, Kathleen M. Darcy, G. Larry Maxwell, Thomas P. Conrads, Timothy D. O'Connor
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103665- (2022)
Summary: Characterization of ancestry-linked peptide variants in disease-relevant patient tissues represents a foundational step to connect patient ancestry with disease pathogenesis. Nonsynonymous single-nucleotide polymorphisms encoding missense su
Externí odkaz:
https://doaj.org/article/42f3b07165c64208ac3226a2c8ca6ac9
Autor:
Nicholas W. Bateman, Pang‐Ning Teng, Erica Hope, Brian L. Hood, Julie Oliver, Wei Ao, Ming Zhou, Guisong Wang, Domenic Tommarello, Katlin Wilson, Tracy Litzy, Kelly A. Conrads, Chad A. Hamilton, Kathleen M. Darcy, Yovanni Casablanca, George Larry Maxwell, Victoria Bae‐Jump, Thomas P. Conrads
Publikováno v:
Cancer Medicine, Vol 9, Iss 3, Pp 1092-1103 (2020)
Abstract Preoperative use of metformin in obese women with endometrioid endometrial cancer (EEC) reduces tumor proliferation and inhibits the mammalian target of rapamycin pathway, though is only effective in select cases. This study sought to identi
Externí odkaz:
https://doaj.org/article/175e0bc27b9348a3a49bceb4ddbd3c53
Autor:
Allison L. Hunt, Nicholas W. Bateman, Waleed Barakat, Sasha Makohon-Moore, Brian L. Hood, Kelly A. Conrads, Ming Zhou, Valerie Calvert, Mariaelena Pierobon, Jeremy Loffredo, Tracy J. Litzi, Julie Oliver, Dave Mitchell, Glenn Gist, Christine Rojas, Brian Blanton, Emma L. Robinson, Kunle Odunsi, Anil K. Sood, Yovanni Casablanca, Kathleen M. Darcy, Craig D. Shriver, Emanuel F. Petricoin, Uma N.M. Rao, G. Larry Maxwell, Thomas P. Conrads
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102757- (2021)
Summary: Enriched tumor epithelium, tumor-associated stroma, and whole tissue were collected by laser microdissection from thin sections across spatially separated levels of ten high-grade serous ovarian carcinomas (HGSOCs) and analyzed by mass spect
Externí odkaz:
https://doaj.org/article/21f41dbd23e4460e8c8c8ab699aed5b8
Autor:
Yovanni Casablanca, Guisong Wang, Heather A. Lankes, Chunqiao Tian, Nicholas W. Bateman, Caela R. Miller, Nicole P. Chappell, Laura J. Havrilesky, Amy Hooks Wallace, Nilsa C. Ramirez, David S. Miller, Julie Oliver, Dave Mitchell, Tracy Litzi, Brian E. Blanton, William J. Lowery, John I. Risinger, Chad A. Hamilton, Neil T. Phippen, Thomas P. Conrads, David Mutch, Katherine Moxley, Roger B. Lee, Floor Backes, Michael J. Birrer, Kathleen M. Darcy, George Larry Maxwell
Publikováno v:
Cancers, Vol 14, Iss 17, p 4070 (2022)
Objectives: A risk assessment model for metastasis in endometrioid endometrial cancer (EEC) was developed using molecular and clinical features, and prognostic association was examined. Methods: Patients had stage I, IIIC, or IV EEC with tumor-derive
Externí odkaz:
https://doaj.org/article/486a382b77b84a11aa60044eef250348
Autor:
Ana Paucarmayta, Hannah Taitz, Latoya McGlorthan, Yovanni Casablanca, G. Larry Maxwell, Kathleen M. Darcy, Viqar Syed
Publikováno v:
Biomedicines, Vol 8, Iss 4, p 73 (2020)
Initially, patients that respond to cisplatin (DDP) treatment later relapse and develop chemoresistance. Agents that enhance DDP effectiveness will have a significant impact on cancer treatment. We have shown pronounced inhibitory effects of the prog
Externí odkaz:
https://doaj.org/article/f48d1d542d6d4e0f859edced7f56dfc7
Publikováno v:
Molecules, Vol 24, Iss 20, p 3722 (2019)
Nitric oxide (NO) is implicated in several biological processes, including cancer progression. At low concentrations, it promotes cell survival and tumor progression, and at high concentrations it causes apoptosis and cell death. Until now, the impac
Externí odkaz:
https://doaj.org/article/0b7f93c3ddd1460b9adcff2d4b32f3bb
Autor:
Eun-Young, Kang, Ashley, Weir, Nicola S, Meagher, Kyo, Farrington, Gregg S, Nelson, Prafull, Ghatage, Cheng-Han, Lee, Marjorie J, Riggan, Adelyn, Bolithon, Gordana, Popovic, Betty, Leung, Katrina, Tang, Neil, Lambie, Joshua, Millstein, Jennifer, Alsop, Michael S, Anglesio, Beyhan, Ataseven, Ellen, Barlow, Matthias W, Beckmann, Jessica, Berger, Christiani, Bisinotto, Hans, Bösmüller, Jessica, Boros, Alison H, Brand, Angela, Brooks-Wilson, Sara Y, Brucker, Michael E, Carney, Yovanni, Casablanca, Alicia, Cazorla-Jiménez, Paul A, Cohen, Thomas P, Conrads, Linda S, Cook, Penny, Coulson, Madeleine, Courtney-Brooks, Daniel W, Cramer, Philip, Crowe, Julie M, Cunningham, Cezary, Cybulski, Kathleen M, Darcy, Mona A, El-Bahrawy, Esther, Elishaev, Ramona, Erber, Rhonda, Farrell, Sian, Fereday, Anna, Fischer, María J, García, Simon A, Gayther, Aleksandra, Gentry-Maharaj, C Blake, Gilks, Marcel, Grube, Paul R, Harnett, Shariska Petersen, Harrington, Philipp, Harter, Arndt, Hartmann, Jonathan L, Hecht, Sebastian, Heikaus, Alexander, Hein, Florian, Heitz, Joy, Hendley, Brenda Y, Hernandez, Susanna Hernando, Polo, Sabine, Heublein, Akira, Hirasawa, Estrid, Høgdall, Claus K, Høgdall, Hugo M, Horlings, David G, Huntsman, Tomasz, Huzarski, Andrea, Jewell, Mercedes, Jimenez-Linan, Michael E, Jones, Scott H, Kaufmann, Catherine J, Kennedy, Dineo, Khabele, Felix K F, Kommoss, Roy F P M, Kruitwagen, Diether, Lambrechts, Nhu D, Le, Marcin, Lener, Jenny, Lester, Yee, Leung, Anna, Linder, Liselore, Loverix, Jan, Lubiński, Rashna, Madan, G Larry, Maxwell, Francesmary, Modugno, Susan L, Neuhausen, Alexander, Olawaiye, Siel, Olbrecht, Sandra, Orsulic, José, Palacios, Celeste Leigh, Pearce, Malcolm C, Pike, Carmel M, Quinn, Ganendra Raj, Mohan, Cristina, Rodríguez-Antona, Matthias, Ruebner, Andy, Ryan, Stuart G, Salfinger, Naoko, Sasamoto, Joellen M, Schildkraut, Minouk J, Schoemaker, Mitul, Shah, Raghwa, Sharma, Yurii B, Shvetsov, Naveena, Singh, Gabe S, Sonke, Linda, Steele, Colin J R, Stewart, Karin, Sundfeldt, Anthony J, Swerdlow, Aline, Talhouk, Adeline, Tan, Sarah E, Taylor, Kathryn L, Terry, Aleksandra, Tołoczko, Nadia, Traficante, Koen K, Van de Vijver, Maaike A, van der Aa, Toon, Van Gorp, Els, Van Nieuwenhuysen, Lilian, van-Wagensveld, Ignace, Vergote, Robert A, Vierkant, Chen, Wang, Lynne R, Wilkens, Stacey J, Winham, Anna H, Wu, Javier, Benitez, Andrew, Berchuck, Francisco J, Candido Dos Reis, Anna, DeFazio, Peter A, Fasching, Ellen L, Goode, Marc T, Goodman, Jacek, Gronwald, Beth Y, Karlan, Stefan, Kommoss, Usha, Menon, Hans-Peter, Sinn, Annette, Staebler, James D, Brenton, David D, Bowtell, Paul D P, Pharoah, Susan J, Ramus, Martin, Köbel
Publikováno v:
Cancer, 129(5), 697-713. Wiley
Cancer: interdisciplinary international journal of the American Cancer Society
Cancer: interdisciplinary international journal of the American Cancer Society
BACKGROUND: Cyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and CCNE1 overexpression with sur
Autor:
John K, Chan, Chunqiao, Tian, Joshua P, Kesterson, Michael T, Richardson, Ken, Lin, Krishnansu S, Tewari, Thomas, Herzog, Daniel S, Kapp, Bradley J, Monk, Yovanni, Casablanca, Parviz, Hanjani, Robert M, Wenham, Joan, Walker, Leah, McNally, Larry J, Copeland, Sharon, Robertson, Samuel, Lentz, Nick M, Spirtos, Jeffery G, Bell
Publikováno v:
Gynecologic Oncology. 167:429-435
To determine the clinical and prognostic significance of CA-125 trends prior to, during, and after chemotherapy in high-risk early-stage epithelial ovarian cancer patients.All patients were enrolled in a phase III randomized trial (GOG 157) following