Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Youwei, Xu"'
Autor:
Sanshan Jin, Shimeng Guo, Youwei Xu, Xin Li, Canrong Wu, Xinheng He, Benxun Pan, Wenwen Xin, Heng Zhang, Wen Hu, Yuling Yin, Tianwei Zhang, Kai Wu, Qingning Yuan, H. Eric Xu, Xin Xie, Yi Jiang
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis, making QRFPR an attractive
Externí odkaz:
https://doaj.org/article/1dd02c6ef3f34c349ea569c47548e552
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114511- (2024)
Summary: Bombesin receptor subtype-3 (BRS3) is an important orphan G protein-coupled receptor that regulates energy homeostasis and insulin secretion. As a member of the bombesin receptor (BnR) family, the lack of known endogenous ligands and high-re
Externí odkaz:
https://doaj.org/article/854de4b8d8a54817b8b51437325d9661
Autor:
Hongmin Cai, Shimeng Guo, Youwei Xu, Jun Sun, Junrui Li, Zhikan Xia, Yi Jiang, Xin Xie, H. Eric Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The adenosine A3 receptor (A3AR), a key member of the G protein-coupled receptor family, is a promising therapeutic target for inflammatory and cancerous conditions. The selective A3AR agonists, CF101 and CF102, are clinically significant, y
Externí odkaz:
https://doaj.org/article/4814eb6bde874961bae82507728016df
Autor:
Yongxin Lu, Yuwei Zhou, Pengjun Wen, Fan Luo, Jian Cao, Youwei Xu, Shiqing Wang, Xiao Li, Xiaoyong Zhang, Wenya Li
Publikováno v:
Journal of Materials Research and Technology, Vol 27, Iss , Pp 2964-2975 (2023)
K418 alloy was prepared by selective laser melting (SLM) at different laser powers (160∼240 W) in this paper. The influence of laser power on the densification behavior, microstructure, microhardness, and tensile properties was studied systematical
Externí odkaz:
https://doaj.org/article/61816b45e0ee46c8a32b9f529ed1037d
Autor:
Jun Niu, Qi Wang, Wenwen Zhao, Bing Meng, Youwei Xu, Xianfang Zhang, Yi Feng, Qilian Qi, Yanling Hao, Xuan Zhang, Ying Liu, Jiangchao Xiang, Yiming Shao, Bei Yang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Structure-guided immunofocusing HIV-1 vaccine design entails a comprehensive understanding of Envs from diverse HIV-1 subtypes, including circulating recombinant forms (CRFs). Here, we present the cryo-EM structures of Envs from two Asia pre
Externí odkaz:
https://doaj.org/article/72a7e6a3b85d4ed9a39e7206d9e05b90
Autor:
Peiwen Jiang, Youwei Xu, Shuai Zhang, Shannan Xu, Yancong Cai, Yutao Yang, Zuozhi Chen, Min Li
Publikováno v:
Ecological Indicators, Vol 160, Iss , Pp 111893- (2024)
Comprehending fish diversity through multiple dimensions is a crucial aspect in advancing our understanding of fish populations and promoting sustainable fisheries as well as diversity conservation. Traditional research on fish diversity has been lim
Externí odkaz:
https://doaj.org/article/b2b93e80b7dd41a0a1a91dba0b4505bc
Publikováno v:
Ecological Indicators, Vol 160, Iss , Pp 111758- (2024)
Understanding the impact of climate change on the distribution of marine species is of vital importance for the sustainable development of marine fisheries. In this study, an ensemble species distribution model is employed to predict the potential di
Externí odkaz:
https://doaj.org/article/76d44dd4ac8b40f583017b7b86d99dd8
Autor:
Canrong Wu, Youwei Xu, Qian He, Dianrong Li, Jia Duan, Changyao Li, Chongzhao You, Han Chen, Weiliang Fan, Yi Jiang, H. Eric Xu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Prostaglandin F2α (PGF2α), an endogenous arachidonic acid metabolite, regulates diverse physiological functions in many tissues and cell types through binding and activation of a G-protein-coupled receptor (GPCR), the PGF2α receptor (FP),
Externí odkaz:
https://doaj.org/article/47b05886e76b4dfca9555b7c350fb9e2
Autor:
Yan Chen, Qingtong Zhou, Jiang Wang, Youwei Xu, Yun Wang, Jiahui Yan, Yibing Wang, Qi Zhu, Fenghui Zhao, Chenghao Li, Chuan-Wei Chen, Xiaoqing Cai, Ross A .D. Bathgate, Chun Shen, H. Eric Xu, Dehua Yang, Hong Liu, Ming-Wei Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Relaxin family peptide receptor 4 (RXFP4) regulates pleiotropic biological processes. Here, authors report cryo-EM structures revealing the ligand-binding modes and key determinants of peptidomimetic agonism and subtype selectivity
Externí odkaz:
https://doaj.org/article/f964b0fe766549098887ae712849b234
Autor:
Hongmin Cai, Youwei Xu, Shimeng Guo, Xinheng He, Jun Sun, Xin Li, Changyao Li, Wanchao Yin, Xi Cheng, Hualiang Jiang, H. Eric Xu, Xin Xie, Yi Jiang
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/68bdf1b0e0cb472a845e01d9baa18108