Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

Autor: Al-Sanea MM, Gotina L, Mohamed MFA, Grace Thomas Parambi D, Gomaa HAM, Mathew B, Youssif BGM, Alharbi KS, Elsayed ZM, Abdelgawad MA, Eldehna WM

Publikováno v: Drug Design, Development and Therapy, Vol Volume 14, Pp 497-508 (2020)

Mohammad M Al-Sanea,1 Lizaveta Gotina,2 Mamdouh FA Mohamed,3 Della Grace Thomas Parambi,1 Hesham A M Gomaa,4,5 Bijo Mathew,6 Bahaa G M Youssif,7 Khalid Saad Alharbi,8 Zainab M Elsayed,9 Mohamed A Abdelgawad,1,10 Wagdy M Eldehna9,11 1Department of Pha

Externí odkaz: https://doaj.org/article/c1a39e7700174182a2be2b74743ae36f

Synthesis and anti-mycobacterial activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: revitalizing an old drug.

Autor: Abdu-Allah HH; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt. hagag.abdallah@pharm.au.edu.eg., Youssif BG; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt.; Department of Pharmaceutical Chemistry, College of Pharmacy, Aljouf University, Aljouf, Sakaka, 42421, Saudi Arabia., Abdelrahman MH; Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt., Abdel-Hamid MK; Medicinal Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt., Reshma RS; Medicinal Chemistry and Antimycobacterial Research Laboratory, Pharmacy Group, Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Jawahar Nagar, Hyderabad, Telangana, 500078, India., Yogeeswari P; Medicinal Chemistry and Antimycobacterial Research Laboratory, Pharmacy Group, Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Jawahar Nagar, Hyderabad, Telangana, 500078, India., Aboul-Fadl T; Medicinal Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt., Sriram D; Medicinal Chemistry and Antimycobacterial Research Laboratory, Pharmacy Group, Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Jawahar Nagar, Hyderabad, Telangana, 500078, India. dsriram@hyderabad.bits-pilani.ac.in.

Publikováno v: Archives of pharmacal research [Arch Pharm Res] 2017 Feb; Vol. 40 (2), pp. 168-179. Date of Electronic Publication: 2016 Dec 27.

2-Nitroimidazole-tricarbocyanine conjugate as a near-infrared fluorescent probe for in vivo imaging of tumor hypoxia.

Autor: Okuda K; Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, Gifu 501-1196, Japan., Okabe Y, Kadonosono T, Ueno T, Youssif BG, Kizaka-Kondoh S, Nagasawa H

Publikováno v: Bioconjugate chemistry [Bioconjug Chem] 2012 Mar 21; Vol. 23 (3), pp. 324-9. Date of Electronic Publication: 2012 Feb 22.