Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Youssef Yakkioui"'
LIM and SH3 protein 1 (LASP1) differentiates malignant chordomas from less malignant chondrosarcomas
Autor:
Cas Vanderheijden, Thomas Vaessen, Youssef Yakkioui, Robert Riedl, Yasin Temel, Koos Hovinga, Govert Hoogland
Publikováno v:
Journal of Neuro-Oncology, 158(1), 81-88. Springer, Cham
Purpose Chordomas are malignant tumors that develop along the neuraxis between skull-base and sacrum. Chondrosarcomas show similarities with chordomas, yet show less malignant behavior. LIM and SH3 protein 1 (LASP1) is a cytoskeletal protein known to
Autor:
Youssef Yakkioui, Cas Vanderheijden, Koos Hovinga, Thomas Vaessen, Govert Hoogland, Yasin Temel
Publikováno v:
World Neurosurgery. 156:125-132
Purpose A chordoma is a slow-growing, invasive neoplasm in the neuraxis, thought to arise from notochordal cells. At 10-year follow-up, the average survival rate is 50%, though the interindividual prognosis varies substantially. Here, we aim to provi
Autor:
Axel zur Hausen, Sreedhar Pujari, Youssef Yakkioui, Jacobus J. van Overbeeke, Ernst-Jan M. Speel, Petra F. G. Wolffs, Merel J.M. Boderie, Yasin Temel
Publikováno v:
World Neurosurgery, 112, E7-E13. Elsevier Science
Background Chordomas are rare tumors assumed to derive from notochordal remnants. We believe that a molecular switch is responsible for their malignant behavior. The involvement of oncogenic viruses has not been studied, however. Thus, in the present
Autor:
Donald E. Born, Joshua W. Osbun, Philip D. Tatman, Manuel Ferreira, Sumanpret Kaur, Jing Zhang, Owais Ahmad, Youssef Yakkioui
Publikováno v:
Journal of Neurological Surgery Part B: Skull Base. 78:S1-S156
Autor:
Sumanpret Kaur, Donald E. Born, Carolina Parada, Philip D. Tatman, Owais Ahmad, Tina Busald, Manuel Ferreira, Youssef Yakkioui, Jing Zhang, Joshua W. Osbun
Publikováno v:
World Neurosurgery, 107, 75-81. Elsevier Science
BACKGROUND: Chordomas and chondrosarcomas can occur in the skull base. Currently, 45% of chordomas and 56% of chondrosarcomas recur within 5 years of surgery. The role of adjuvant therapy is highly debated. No pharmacotherapies have been approved by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbe9c9cf2a8071eea8feb6972cc097e
https://cris.maastrichtuniversity.nl/en/publications/1ceb7e8f-d0a1-4b4b-9c40-1d968d008a6c
https://cris.maastrichtuniversity.nl/en/publications/1ceb7e8f-d0a1-4b4b-9c40-1d968d008a6c
Autor:
Jacobus J. van Overbeeke, Youssef Yakkioui, Yasin Temel, Manon van Engeland, Remco Santegoeds
Publikováno v:
Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides, 1846(2), 655-69. Elsevier BV
Chordomas are malignant tumors of the axial skeleton, characterized by their locally invasive and slow but aggressive growth. These neoplasms are presumed to be derived from notochordal remnants with a molecular alteration preceding their malignant t
Publikováno v:
Surgical Neurology International
Surgical Neurology International, 8(1):196. Medknow Publications and Media Pvt. Ltd.
Surgical Neurology International, 8(1):196. Medknow Publications and Media Pvt. Ltd.
BACKGROUND: Cholesterol granulomas (CG) of the petrous apex (CGPA) are benign lesions that have high recurrence rates after surgical intervention. We describe the use of a robust silicon drain between the petrous apex and mastoid air cells to allow c
Autor:
Jing Zhang, Joshua W. Osbun, Yigit Karasozen, Luis F. Gonzalez-Cuyar, Youssef Yakkioui, Manuel Ferreira, Sumanpreet Kaur, Tina Busald, Robert C. Rostomily, Catherine Pan, Min Shi, Carolina Parada
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
There is a need to better understand meningioma oncogenesis for biomarker discovery and development of targeted therapies. Histological or genetic criteria do not accurately predict aggressiveness. Post-translational studies in meningioma progression
Autor:
Yasin Temel, J. J. Van Overbeeke, Govert Hoogland, Ali Jahanshahi, Youssef Yakkioui, R G C Santegoeds
Publikováno v:
Surgical Neurology International
Surgical Neurology International, 8(1):100. Medknow Publications and Media Pvt. Ltd.
Surgical Neurology International, 8(1):100. Medknow Publications and Media Pvt. Ltd.
BACKGROUND: Chordoma are rare slow-growing tumors of the axial skeleton, which are thought to arise from remnants of the notochord. Little is known about the underlying mechanisms that drive this tumor. However, the assessment of gene expression leve