Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Youssef A Kousa"'
Autor:
Steven Goudy, Peggi Angel, Britni Jacobs, Cynthia Hill, Veronica Mainini, Arianna L Smith, Youssef A Kousa, Richard Caprioli, Lawrence S Prince, Scott Baldwin, Brian C Schutte
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56270 (2013)
Interferon regulatory factor 6 (IRF6) encodes a highly conserved helix-turn-helix DNA binding protein and is a member of the interferon regulatory family of DNA transcription factors. Mutations in IRF6 lead to isolated and syndromic forms of cleft li
Externí odkaz:
https://doaj.org/article/c1d2ac7c32af420c8d9782a740c42130
Autor:
Youssef A. Kousa, Reafa A. Hossain
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 6, Iss 2, p 95 (2021)
Prenatal viral infection can lead to a spectrum of neurodevelopmental disabilities or fetal demise. These can include microencephaly, global developmental delay, intellectual disability, refractory epilepsy, deafness, retinal defects, and cortical-vi
Externí odkaz:
https://doaj.org/article/debce84b57f94024a41766cd301ee806
Autor:
Roberta L. DeBiasi, Nada Harik, Stephanie Russo, Lindsay Pesacreta, Gilbert Vezina, Emily Ansusinha, Adre J. du Plessis, Tracey Ambrose, Rana F Hamdy, Youssef A Kousa, Benjamin Hanisch, Caitlin Cristante, Dorothy I. Bulas, David L. Wessel, Andrea Hahn, Mohamad S. Jaafar, Barbara Jantausch, Taeun Chang, Cara Biddle, Sarah B. Mulkey
Publikováno v:
Am J Trop Med Hyg
The objective of the study was to describe the complexity of diagnosis and evaluation of Zika-exposed pregnant women/fetuses and infants in a U.S. Congenital Zika Program. Pregnant women/fetuses and/or infants referred for clinical evaluation to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa9e1d7bf266b49a2702ecbf0aa2c0e
https://doi.org/10.4269/ajtmh.20-1256
https://doi.org/10.4269/ajtmh.20-1256
Autor:
Reafa A. Hossain, Youssef A. Kousa
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 6, Iss 95, p 95 (2021)
Tropical Medicine and Infectious Disease
Tropical Medicine and Infectious Disease
Prenatal viral infection can lead to a spectrum of neurodevelopmental disabilities or fetal demise. These can include microencephaly, global developmental delay, intellectual disability, refractory epilepsy, deafness, retinal defects, and cortical-vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8d89251e9bb5c4bbccdc11f9860617
https://www.mdpi.com/2414-6366/6/2/95
https://www.mdpi.com/2414-6366/6/2/95
Publikováno v:
Journal of Child Neurology. 34:820-823
Here we report the case of a previously healthy 8-year-old boy who presented with altered mental status, right facial droop and right-sided hemiplegia the day after playing in an inflatable bouncer. No head trauma was reported by the patient nor witn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682b2634f485776a6979b1e734cae9cb
https://doi.org/10.1177/0883073819861851
https://doi.org/10.1177/0883073819861851
Autor:
Walid D. Fakhouri, Yunping Lei, Tamara Busch, Simon G. Gregory, Wei Yang, Richard H. Finnell, Arianna L. Smith, Edward Li, Alexander G. Bassuk, Gary M. Shaw, Huiping Zhu, Trevor Williams, Youssef A. Kousa, Tamer A. Mansour, Yang Chai, A. J. Agopian, Laura E. Mitchell, Akira Kinoshita, Brad A. Amendt, Elizabeth J. Leslie, Brian C. Schutte, Eric C. Liao, Xiao Li, Dhruv B. Sharma, Nicole K Patel, Raeuf Roushangar, Allison E. Ashley-Koch
Publikováno v:
Hum Mol Genet
Mutations in IRF6, TFAP2A and GRHL3 cause orofacial clefting syndromes in humans. However, Tfap2a and Grhl3 are also required for neurulation in mice. Here, we found that homeostasis of Irf6 is also required for development of the neural tube and ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe0c76be9040181391af9fb105ce5b5
https://doi.org/10.1093/hmg/ddz010
https://doi.org/10.1093/hmg/ddz010
Publikováno v:
Journal of Investigative Dermatology. 138:2578-2588
Variants in IRF6 can lead to Van der Woude syndrome and popliteal pterygium syndrome. Furthermore, genes upstream and downstream of IRF6, including GRHL3 and TP63, are also associated with orofacial clefting. Additionally, a variant in an enhancer (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381400d8d137ffa9ab2b2850af2489b8
https://doi.org/10.1016/j.jid.2018.05.030
https://doi.org/10.1016/j.jid.2018.05.030
Autor:
Karl B. Seydel, Chenxi Li, Gretchen L. Birbeck, Terrie E. Taylor, Peter W. Kaplan, Robert O. Opoka, Chandy C. John, Douglas G. Postels, Xiaoting Wu, Richard Idro, Youssef A. Kousa
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-10 (2018)
Malaria Journal
Malaria Journal
Background Electroencephalography at hospital presentation may offer important insights regarding prognosis that can inform understanding of cerebral malaria (CM) pathophysiology and potentially guide patient selection and risk stratification for fut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c24c095fa6197b0e2f513508b84e40
http://link.springer.com/article/10.1186/s12936-018-2355-9
http://link.springer.com/article/10.1186/s12936-018-2355-9
Autor:
Youssef A. Kousa, Caitlin Cristante, Roberta L. DeBiasi, Gilbert Vezina, Zarir Khademian, Adre J. du Plessis, Lindsay Pesacreta, Dorothy I. Bulas, Anna R. Blask, Sarah B. Mulkey
Publikováno v:
Pediatric Neurology. 78:75-78
Background Congenital Zika infection can result in a spectrum of neurological abnormalities in the newborn. Newborns exposed to Zika virus in utero often have neuroimaging as part of their clinical evaluation. Methods Through the Congenital Zika Prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267ff1975ad7ff09b248bd1e55e409df
https://doi.org/10.1016/j.pediatrneurol.2017.10.012
https://doi.org/10.1016/j.pediatrneurol.2017.10.012
Autor:
Brian C. Schutte, Sarah Bakhiet, Youssef A. Kousa, Kareem Metwalli, Walid D. Fakhouri, Ali Naji, Angela Quispe-Salcedo, Larissa Nitschke
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Interferon Regulatory Factor 6 (IRF6) and TWIST1 are transcription factors necessary for craniofacial development. Human genetic studies showed that mutations in IRF6 lead to cleft lip and palate and mandibular abnormalities. In the mouse, we found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22e68de3f015b5670de79499e4a287c
https://doaj.org/article/b269d22767a14456a5a09864fa5151e1
https://doaj.org/article/b269d22767a14456a5a09864fa5151e1