Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yousif A. Kariri"'
Autor:
Corinne L. Woodcock, Mansour Alsaleem, Michael S. Toss, Jennifer Lothion-Roy, Anna E. Harris, Jennie N. Jeyapalan, Nataliya Blatt, Albert A. Rizvanov, Regina R. Miftakhova, Yousif A. Kariri, Srinivasan Madhusudan, Andrew R. Green, Catrin S. Rutland, Rupert G. Fray, Emad A. Rakha, Nigel P. Mongan
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background N6-methyladenosine (m6A) is the most common internal RNA modification and is involved in regulation of RNA and protein expression. AlkB family member 5 (ALKBH5) is a m6A demethylase. Given the important role of m6A in biological m
Externí odkaz:
https://doaj.org/article/8fdaac6eb0dd41889920c42b595de135
Autor:
Omar J. Mohammed, Michael S. Toss, Emad A. Rakha, Chitra Joseph, Mansour Alsaleem, Sami Alsaeed, Yousif A Kariri, Andrew R. Green, Abrar I. Aljohani, Sho Shiino
Publikováno v:
Breast Cancer Research and Treatment
Background Lymphovascular invasion (LVI) is a prognostic factor in early-stage invasive breast cancer (BC). Through bioinformatics, data analyses of multiple BC cohorts revealed the positive association between interferon-stimulated gene 15 (ISG15) L
Autor:
Yousif A. Kariri, Chitra Joseph, Mansour A. Alsaleem, Khloud A. Elsharawy, Sami Alsaeed, Michael S. Toss, Nigel P. Mongan, Andrew R. Green, Emad A. Rakha
Publikováno v:
Cancers; Volume 14; Issue 22; Pages: 5643
Background: Cell Division Cycle Associated 5 (CDCA5) plays a role in the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signalling pathway involving cell division, cancer cell migration and apoptosis. This study aims to assess the prognostic and biologica
Autor:
Michael S. Toss, Emad A. Rakha, Andrew R. Green, Yousif A Kariri, Pavan L. Narasimha, Chitra Joseph, Nigel P. Mongan, Mansour Alsaleem, Maryam Althobiti, Abrar I. Aljohani, Sami Alsaeed
Publikováno v:
Cancers
Volume 13
Issue 1
Cancers, Vol 13, Iss 80, p 80 (2021)
Volume 13
Issue 1
Cancers, Vol 13, Iss 80, p 80 (2021)
Simple Summary Breast cancer exhibits significant genetic and clinical heterogeneity. Given the importance of understanding tumour-immune interactions to enable the development of novel immunotherapies, identification of novel prognostic biomarkers i
Autor:
Omar J. Mohammed, Michael S. Toss, Emad A. Rakha, Yousif A Kariri, Mohammed A. Aleskandarany, Andrew R. Green, Sasagu Kurozumi, Chitra Joseph
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology. 87(4)
Lymphovascular invasion (LVI) is associated with poor outcome in breast cancer (BC); however, its underlying mechanisms remain ill-defined. LVI in BC develops through complex molecular pathways involving not only the interplay with the surrounding mi
Autor:
Chitra Joseph, Andrew R. Green, Sultan N Sonbul, Sami Alsaeed, Mansour Alsaleem, Nigel P. Mongan, Stewart G. Martin, Ian O. Ellis, Takaaki Fujii, Christopher C. Nolan, Sasagu Kurozumi, Yousif A Kariri, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Simon J Johnston, Emad A. Rakha, Marian Pigera, Ken Shirabe
Publikováno v:
Breast Cancer Research and Treatment. 172:61-68
BACKGROUND: Ras association and pleckstrin homology domains 1 (RAPH1) is involved in cytoskeleton regulation and re-epithelialisation in invasive carcinoma and therefore may play a key role in carcinogenesis and metastasis. We herein investigated the
Autor:
Carlos Caldas, Sultan N Sonbul, Sasagu Kurozumi, Ibraheem Ashankyty, Yousif A Kariri, Leslie W Dalton, Abrar I. Aljohani, Takaaki Fujii, Andrew R. Green, Ian O. Ellis, Sami Alsaeed, Emad A. Rakha, Ken Shirabe, Sara Raafat, Chitra Joseph, Mohammed A. Aleskandarany, Simon J Johnston, Angela Ogden, Mansour Alsaleem, Nigel P. Mongan, Christine Desmedt
Publikováno v:
British Journal of Cancer
BACKGROUND: Lymphovascular invasion (LVI) is associated with the development of metastasis in invasive breast cancer (BC). However, the complex molecular mechanisms of LVI, which overlap with other oncogenic pathways, remain unclear. This study, usin