Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Yousif, Shamoo"'
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTAntibiotic resistance is a continuing global health crisis. Identifying the evolutionary trajectories leading to increased antimicrobial resistance can be critical to the discovery of biomarkers for clinical diagnostics and new targets for dr
Externí odkaz:
https://doaj.org/article/9315767c91c448b387022a447fd3a67f
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101332- (2022)
Summary: Microdroplet emulsions allow investigators to build controllable microenvironments for applications in experimental evolution and synthetic ecology. We designed a microfluidic platform that uses highly homogenous microdroplets to enable thes
Externí odkaz:
https://doaj.org/article/9f16a278613541b3a33c8cd871f3a576
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Combination antimicrobial therapy has been considered a promising strategy to combat the evolution of antimicrobial resistance. Francisella tularensis is the causative agent of tularemia and in addition to being found in the nature, is recognized as
Externí odkaz:
https://doaj.org/article/1bc069fe5f224c09aa9ce5d0022625f8
Autor:
Jannell V Bazurto, Dipti D Nayak, Tomislav Ticak, Milya Davlieva, Jessica A Lee, Chandler N Hellenbrand, Leah B Lambert, Olivia J Benski, Caleb J Quates, Jill L Johnson, Jagdish Suresh Patel, F Marty Ytreberg, Yousif Shamoo, Christopher J Marx
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001208 (2021)
Normal cellular processes give rise to toxic metabolites that cells must mitigate. Formaldehyde is a universal stressor and potent metabolic toxin that is generated in organisms from bacteria to humans. Methylotrophic bacteria such as Methylorubrum e
Externí odkaz:
https://doaj.org/article/ba4b2563d3db4235ade1603ec90ab87c
Autor:
Ramya Ganiga Prabhakar, Gaoyang Fan, Razan N. Alnahhas, Andrew J. Hirning, Matthew R. Bennett, Yousif Shamoo
Publikováno v:
ACS Synthetic Biology. 12:1239-1251
Spatial structure within microbial communities can provide nearly limitless opportunities for social interactions and are an important driver for evolution. As metabolites are often molecular signals, metabolite diffusion within microbial communities
Autor:
Heer H Mehta, Yousif Shamoo
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008280 (2020)
Externí odkaz:
https://doaj.org/article/e782277756764eb3b8063f6c4a5f1b80
Publikováno v:
ACS Infect Dis
In vitro experimental evolution has complemented clinical studies as an excellent tool to identify genetic changes responsible for the de novo evolution of antimicrobial resistance. However, the in vivo context for adaptation contributes to the succe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbe8f522a50a8b9f3bf4c527a2e6995
https://europepmc.org/articles/PMC9996545/
https://europepmc.org/articles/PMC9996545/
Autor:
Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The validation and analysis of X-ray crystallographic data is essential for reproducibility and the development of crystallographic methods. Here, the authors describe a repository for crystallographic datasets and demonstrate some of the ways it cou
Externí odkaz:
https://doaj.org/article/72383da3679147f9a2668c703d709d2e
Autor:
Seokju Seo, Saoirse Disney-McKeethen, Ramya Ganiga Prabhakar, Xinhao Song, Heer H. Mehta, Yousif Shamoo
Publikováno v:
ACS Infect Dis
In vitro experimental evolution of pathogens to antibiotics is commonly used for the identification of clinical biomarkers associated with antibiotic resistance. Microdroplet emulsions allow exquisite control of spatial structure, species complexity,
The application of microfluidic techniques in experimental and environmental studies is a rapidly emerging field. Water-in-oil microdroplets can serve readily as controllable micro-vessels for studies that require spatial structure. In many applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc99b3775e5b77a88d55a6e031217fe8
https://doi.org/10.1101/2022.12.05.519239
https://doi.org/10.1101/2022.12.05.519239