Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Yousheng, Shu"'
Autor:
Xiaoxue Jiang, Kan liu, Peixiang Luo, Zi Li, Fei Xiao, Haizhou Jiang, Shangming Wu, Min Tang, Feixiang Yuan, Xiaoying Li, Yousheng Shu, Bo Peng, Shanghai Chen, Shihong Ni, Feifan Guo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The central nervous system has been implicated in the age-induced reduction in adipose tissue lipolysis. However, the underlying mechanisms remain unclear. Here, we show the expression of SLC7A14 is reduced in proopiomelanocortin (POMC) neur
Externí odkaz:
https://doaj.org/article/b686d17b05534d49bcd30a7354668d47
Autor:
Di-Xian Wang, Zhao-Jun Dong, Sui-Xin Deng, Ying-Ming Tian, Yu-Jie Xiao, Xinran Li, Xiao-Ru Ma, Liang Li, Pengxiao Li, Hui-Zhong Chang, Longqi Liu, Fan Wang, Yang Wu, Xiang Gao, Shuang-Shuang Zheng, Hui-Min Gu, Ya-Nan Zhang, Jian-Bin Wu, Fan Wu, Yonglin Peng, Xiao-Wen Zhang, Ren-Ya Zhan, Li-Xia Gao, Qiming Sun, Xing Guo, Xiao-Dong Zhao, Jian-Hong Luo, Ruhong Zhou, Lei Han, Yousheng Shu, Jing-Wei Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract As a major neuron type in the brain, the excitatory neuron (EN) regulates the lifespan in C. elegans. How the EN acquires senescence, however, is unknown. Here, we show that growth differentiation factor 11 (GDF11) is predominantly expressed
Externí odkaz:
https://doaj.org/article/2a15719e7dfd444ba38f9bdef7833f9d
Autor:
Fei Xiao, Haizhou Jiang, Zi Li, Xiaoxue Jiang, Shanghai Chen, Yuguo Niu, Hanrui Yin, Yousheng Shu, Bo Peng, Wei Lu, Xiaoying Li, Zhigang Li, Shujue Lan, Xiaoyan Xu, Feifan Guo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract An important role for liver in the regulation of adipose tissue thermogenesis upon cold exposure has been suggested; however, the underlying mechanisms remain incompletely defined. Here, we identify elevated serum bradykinin levels in respon
Externí odkaz:
https://doaj.org/article/c5e163e232a84bf3853467f9a482c1a3
Autor:
Yang He, Taohui Liu, Quansheng He, Wei Ke, Xiaoyu Li, Jinjin Du, Suixin Deng, Zhenfeng Shu, Jialin Wu, Baozhi Yang, Yuqing Wang, Ying Mao, Yanxia Rao, Yousheng Shu, Bo Peng
Publikováno v:
eLife, Vol 12 (2023)
General anesthesia leads to a loss of consciousness and an unrousable state in patients. Although general anesthetics are widely used in clinical practice, their underlying mechanisms remain elusive. The potential involvement of nonneuronal cells is
Externí odkaz:
https://doaj.org/article/3a8f586987ad44a4b67fad1debf8c3f3
Autor:
Lei Tong, Shanshan Han, Yao Xue, Minggang Chen, Fuyi Chen, Wei Ke, Yousheng Shu, Ning Ding, Joerg Bewersdorf, Z. Jimmy Zhou, Peng Yuan, Jaime Grutzendler
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107857- (2023)
Summary: Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation. However, this frequently requires relatively high laser powers. Here, we developed a novel strategy that can improve the efficiency of current two
Externí odkaz:
https://doaj.org/article/994e05984c974dc19a448a79e41e1443
Autor:
Dengfeng Liu, Zhengyu Xie, Panyang Gu, Xiangyu Li, Yichun Zhang, Xinying Wang, Zhiheng Chen, Suixin Deng, Yousheng Shu, Jia-Da Li
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
Attention-deficit hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder that affects approximately 5.3% of children and approximately 2.5% of adults. There is an intimate relationship between ADHD and sleep disturbance. Spec
Externí odkaz:
https://doaj.org/article/11a9b9f389444e1d96790b94fccb24b4
Autor:
Lei Qi, Cuiping Xu, Xueyuan Wang, Jialin Du, Quansheng He, Di Wu, Xiaopeng Wang, Guangyuan Jin, Qiao Wang, Jia Chen, Di Wang, Huaqiang Zhang, Xiaohua Zhang, Penghu Wei, Yongzhi Shan, Zaixu Cui, Yuping Wang, Yousheng Shu, Guoguang Zhao, Tao Yu, Liankun Ren
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Direct electrical stimulation of the basal ganglia using implanted SEEG electrodes produced a variety of motor and non-motor effects in human participants, providing insight into the functional architecture of this key brain region.
Externí odkaz:
https://doaj.org/article/3d97eec9fc0d4911ac337939865fe712
Autor:
Tian Zhou, Yuxin Li, Xiaoyu Li, Fanzhuo Zeng, Yanxia Rao, Yang He, Yafei Wang, Meizhen Liu, Dali Li, Zhen Xu, Xin Zhou, Siling Du, Fugui Niu, Jiyun Peng, Xifan Mei, Sheng-Jian Ji, Yousheng Shu, Wei Lu, Feifan Guo, Tianzhun Wu, Ti-Fei Yuan, Ying Mao, Bo Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Microglia are professional phagocytes in the CNS. However, which cells scavenge corpses of microglia is largely neglected. Peng and colleagues found that nonprofessional phagocytes (astrocyte) phagocytose the debris of professional phagocytes (microg
Externí odkaz:
https://doaj.org/article/d6e7d054ad5143fa9bf9501f7b92f302
Autor:
Xiao-Ru Ma, Xudong Zhu, Yujie Xiao, Hui-Min Gu, Shuang-Shuang Zheng, Liang Li, Fan Wang, Zhao-Jun Dong, Di-Xian Wang, Yang Wu, Chenyu Yang, Wenhong Jiang, Ke Yao, Yue Yin, Yang Zhang, Chao Peng, Lixia Gao, Zhuoxian Meng, Zeping Hu, Chong Liu, Li Li, Hou-Zao Chen, Yousheng Shu, Zhenyu Ju, Jing-Wei Zhao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Age-dependent decline in remyelination in the CNS is associated with declined differentiation capacity of oligodendrocyte progenitor cells (OPCs). Here, the authors show nuclear entry of SIRT2 is impaired and NAD+ levels are reduced during ageing in
Externí odkaz:
https://doaj.org/article/5e54229427a044a9afccbf8998af649c
Autor:
Xiaoxue Jiang, Kan Liu, Haizhou Jiang, Hanrui Yin, En-duo Wang, Hong Cheng, Feixiang Yuan, Fei Xiao, Fenfen Wang, Wei Lu, Bo Peng, Yousheng Shu, Xiaoying Li, Shanghai Chen, Feifan Guo
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111984- (2023)
Summary: Lysosomal amino acid accumulation is implicated in several diseases, but its role in insulin resistance, the central mechanism to type 2 diabetes and many metabolic diseases, is unclear. In this study, we show the hepatic expression of lysos
Externí odkaz:
https://doaj.org/article/59ed0553eff74c9cbe99874180fda098