Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Yousefian-Jazi A"'
Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease
Autor:
Suhyun Kim, Heejung Chun, Yunha Kim, Yeyun Kim, Uiyeol Park, Jiyeon Chu, Mridula Bhalla, Seung-Hye Choi, Ali Yousefian-Jazi, Sojung Kim, Seung Jae Hyeon, Seungchan Kim, Yeonseo Kim, Yeon Ha Ju, Seung Eun Lee, Hyunbeom Lee, Kyungeun Lee, Soo-Jin Oh, Eun Mi Hwang, Junghee Lee, C. Justin Lee, Hoon Ryu
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Background Astrocytes, one of the most resilient cells in the brain, transform into reactive astrocytes in response to toxic proteins such as amyloid beta (Aβ) in Alzheimer’s disease (AD). However, reactive astrocyte-mediated non-cell aut
Externí odkaz:
https://doaj.org/article/10d1c6d648c04589a8cf3caf530fc135
Autor:
Seung-Hye Choi, Ali Yousefian-Jazi, Seung Jae Hyeon, Phuong Thi Thanh Nguyen, Jiyeon Chu, Sojung Kim, Suhyun Kim, Hannah L. Ryu, Neil W. Kowall, Hoon Ryu, Junghee Lee
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive paralysis due to motor neuron degeneration. It has been proposed that epigenetic modification and transcriptional dysregulation
Externí odkaz:
https://doaj.org/article/ce1f5c250fe848ecbc04308709d14522
Akademický článek
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Autor:
Kröger, Hendrik, Nikoubashman, Omid, Dimitrov, Ivaylo, Yousefian Jazi, Ehsan, Schürmann, Kolja, Wiesmann, Martin, Schulz, Jörg B., Reich, Arno
Publikováno v:
In Journal of Stroke and Cerebrovascular Diseases September 2021 30(9)
Autor:
Franz, Christiane, Hasan, Dimah, Yousefian Jazi, Ehsan, Stockero, Andrea, Wiesmann, Martin, Nikoubashman, Omid *
Publikováno v:
In Clinical Neurology and Neurosurgery April 2021 203
Autor:
Choi, Seung-Hye1 (AUTHOR), Yousefian-Jazi, Ali1 (AUTHOR), Hyeon, Seung Jae1 (AUTHOR), Nguyen, Phuong Thi Thanh1,2 (AUTHOR), Chu, Jiyeon1,3 (AUTHOR), Kim, Sojung1 (AUTHOR), Kim, Suhyun1 (AUTHOR), Ryu, Hannah L.4 (AUTHOR), Kowall, Neil W.4,5 (AUTHOR), Ryu, Hoon1,2 (AUTHOR) hoonryu@kist.re.kr, Lee, Junghee4,5 (AUTHOR) junghee@bu.edu
Publikováno v:
Journal of Biomedical Science. 12/20/2022, Vol. 29 Issue 1, p1-18. 18p.
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12499 (2021)
Huntington’s disease (HD) is a rare neurodegenerative disorder caused by an expansion of CAG trinucleotide repeat located in the exon 1 of Huntingtin (HTT) gene in human chromosome 4. The HTT protein is ubiquitously expressed in the brain. Specific
Externí odkaz:
https://doaj.org/article/78e121f2f6d54299b5e949e76ae78752
Power Failure of Mitochondria and Oxidative Stress in Neurodegeneration and Its Computational Models
Autor:
JunHyuk Woo, Hyesun Cho, YunHee Seol, Soon Ho Kim, Chanhyeok Park, Ali Yousefian-Jazi, Seung Jae Hyeon, Junghee Lee, Hoon Ryu
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 229 (2021)
The brain needs more energy than other organs in the body. Mitochondria are the generator of vital power in the living organism. Not only do mitochondria sense signals from the outside of a cell, but they also orchestrate the cascade of subcellular e
Externí odkaz:
https://doaj.org/article/34d2e8bdf124428bb96573e3fab7dec0
Publikováno v:
Cells, Vol 9, Iss 12, p 2687 (2020)
Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease and a neurodegenerative disorder, affecting the upper and/or lower motor neurons. Notably, it invariably leads to death within a few years of onset. Although most ALS cases
Externí odkaz:
https://doaj.org/article/6ceaf16ad486400ab5a6033ad4a3baf1
Autor:
Choi, Seung-Hye, Yousefian-Jazi, Ali, Hyeon, Seung Jae, Nguyen, Phuong Thi Thanh, Chu, Jiyeon, Kim, Sojung, Kim, Suhyun, Ryu, Hannah L., Kowall, Neil W., Ryu, Hoon, Lee, Junghee
Additional file 1: Fig. S1. LSD1 is induced in a cellular model of ALS (N2a cell line). A, LSD1 immunoreactivity (red) was increased in the nucleus of mSOD1 (G85R) N2a cell line. The nucleus was counterstained with DAPI (blue). B, The densitometry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979f1bda4a7d765ea08c05f4d4200cf9
