Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude.

Autor: Kadalayil L; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK., Alam MZ; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.; Department of Computer Science and Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh., White CH; Merck Exploratory Science Center in Cambridge MA, Merck Research Laboratories, Cambridge, MA, 02141, USA., Ghantous A; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France., Walton E; Department of Psychology, University of Bath, Bath, UK., Gruzieva O; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden., Merid SK; Centre for Occupational and Environmental Medicine, Region Stockholm, Sweden., Kumar A; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Roy RP; Helen Diller Family Comprehensive Cancer Center University of California, San Francisco, CA, 94143, USA.; Computational Biology and Informatics Core, University of California, San Francisco, CA, 94143, USA., Solomon O; Children's Environmental Health Laboratory, University of California, Berkeley, CA, USA., Huen K; Children's Environmental Health Laboratory, University of California, Berkeley, CA, USA., Eskenazi B; Children's Environmental Health Laboratory, University of California, Berkeley, CA, USA., Rzehak P; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Grote V; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Langhendries JP; CHC, St Vincent, Liège-Rocourt, Belgium., Verduci E; Department of Pediatrics, Vittore Buzzi Children Hospital, University of Milan, Milan, Italy., Ferre N; Pediatric Nutrition and Human Development Research Unit, Universitat Rovira i Virgili, IISPV, Reus, Spain., Gruszfeld D; Neonatal Department, Children's Memorial Health Institute, Warsaw, Poland., Gao L; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, A460 Mayo Building, MMC 303, 420 Delaware St. SE, Minneapolis, MN, 55455, USA., Zeng X; Glotech, Inc., Rockville, MD, USA., Schisterman EF; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA, 19104, USA., Dou JF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA., Bakulski KM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA., Feinberg JI; Wendy Klag Center for Autism and Developmental Disabilities Johns Hopkins University, Baltimore, MD, USA.; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Soomro MH; Sorbonne Université and INSERM, Epidemiology of Allergic and Respiratory Diseases Department, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris Cedex 12, France.; Department of Community Medicine and Public Health, SMBB Medical University, Larkana, Pakistan., Pesce G; Sorbonne Université and INSERM, Epidemiology of Allergic and Respiratory Diseases Department, Pierre Louis Institute of Epidemiology and Public Health (IPLESP UMRS 1136), Saint-Antoine Medical School, Paris Cedex 12, France., Baiz N; Institut Desbrest de Santé Publique (IDESP), INSERM and Montpellier University, Montpellier, France., Isaevska E; Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, CPO Piemonte, Italy., Plusquin M; Center for Environmental Sciences, University of Hasselt, 3590, Diepenbeek, Belgium., Vafeiadi M; Department of Social Medicine, School of Medicine, University of Crete, Heraklion, Greece., Roumeliotaki T; Department of Social Medicine, School of Medicine, University of Crete, Heraklion, Greece., Langie SAS; Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium.; Faculty of Sciences, Hasselt University, Diepenbeek, Belgium.; Department of Pharmacology and Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Limburg, The Netherlands., Standaert A; Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium., Allard C; Centre de Recherche du Centre Hospitalier de l'Universite de Sherbrooke, Sherbrooke, Canada., Perron P; Department of Medicine, Universite de Sherbrooke, Sherbrooke, Canada., Bouchard L; Department of Biochemistry and Functional Genomics, Universite de Sherbrooke, Sherbrooke, Canada.; Clinical Department of Laboratory Medicine, Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean - Hôpital de Chicoutimi, Chicoutimi, Canada., van Meel ER; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Division of Respiratory Medicine and Allergology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Yousefi PD; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK., Ramlau-Hansen CH; Department of Public Health, Aarhus University, Aarhus, Denmark., Relton CL; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK., Tobi EW; Periconceptional Epidemiology, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Starling AP; Life Course Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Yang IV; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, USA., Llambrich M; Institute for Global Health (ISGlobal), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Santorelli G; Bradford Institute for Health Research, Bradford, UK., Lepeule J; Institute for Advanced Biosciences, University Grenoble-Alpes, INSERM, CNRS, Grenoble, France., Salas LA; Institute for Global Health (ISGlobal), Barcelona, Spain.; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Center for Molecular Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Lebanon, NH, USA., Bustamante M; Institute for Global Health (ISGlobal), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Ewart SL; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA., Zhang H; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, USA., Karmaus W; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, USA., Röder S; Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany., Zenclussen AC; Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany., Jin J; 2530 Meridian Pkwy, Suite 200, Durham, NC 27713, USA., Nystad W; Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway., Page CM; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.; Section for Statistics and Data Science, Department of Mathematics, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway., Magnus M; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., Jima DD; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.; Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA., Hoyo C; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA., Maguire RL; Department of Biological Sciences, North Carolina State University, Raleigh, NC, USA.; Department of Obstetrics and Gynaecology, Duke University Medical Center, Durham, NC, USA., Kvist T; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland., Czamara D; Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, 80804, Munich, Germany., Räikkönen K; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland., Gong T; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Ullemar V; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Rifas-Shiman SL; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA., Oken E; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA., Almqvist C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lahti J; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland., Murphy SK; Department of Obstetrics and Gynaecology, Duke University Medical Center, Durham, NC, USA., Håberg SE; Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway., London S; Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, RTP, NC, 27709, USA., Herberth G; Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany., Arshad H; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; David Hide Asthma and Allergy Research Centre, Isle of Wight, UK.; NIHR Southampton Biomedical Research Centre, Southampton General Hospital, Southampton, UK., Sunyer J; Institute for Global Health (ISGlobal), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Grazuleviciene R; Department of Environmental Science, Vytautas Magnus University, 44248, Kaunas, Lithuania., Dabelea D; Life Course Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Steegers-Theunissen RPM; Periconceptional Epidemiology, Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Nohr EA; Department of Clinical Research, Odense Universitetshospital, Odense, Denmark., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Duijts L; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Division of Respiratory Medicine and Allergology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Division of Neonatology, Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Hivert MF; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA.; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA., Nelen V; Provincial Institute for Hygiene, Antwerp, Belgium., Popovic M; Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, CPO Piemonte, Italy., Kogevinas M; Institute for Global Health (ISGlobal), Barcelona, Spain., Nawrot TS; Center for Environmental Sciences, University of Hasselt, 3590, Diepenbeek, Belgium.; Department of Public Health and Primary Care, Leuven University, Louvain, Belgium., Herceg Z; Epigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France., Annesi-Maesano I; Institut Desbrest de Santé Publique (IDESP), INSERM and Montpellier University, Montpellier, France., Fallin MD; Wendy Klag Center for Autism and Developmental Disabilities Johns Hopkins University, Baltimore, MD, USA.; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Yeung E; Epidemiology Branch, Division of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6710B Rockledge Dr, MSC 7004, Bethesda, MD, USA., Breton CV; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Koletzko B; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, Ludwig-Maximilians Universität München (LMU), Munich, Germany., Holland N; Children's Environmental Health Laboratory, CERCH, Berkeley Public Health, University of California, 2121 Berkeley Way #5216, Berkeley, CA, 94720, USA., Wiemels JL; Center for Genetic Epidemiology, University of Southern California, Los Angeles, CA, 90033, USA.; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90033, USA., Melén E; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Sachs' Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden., Sharp GC; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; School of Psychology, University of Exeter, Exeter, UK., Silver MJ; Medical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, The Gambia.; Medical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine, London, UK., Rezwan FI; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.; Department of Computer Science, Aberystwyth University, Aberystwyth, Ceredigion, UK., Holloway JW; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK. J.W.Holloway@soton.ac.uk.; NIHR Southampton Biomedical Research Centre, Southampton General Hospital, Southampton, UK. J.W.Holloway@soton.ac.uk.

Publikováno v: Clinical epigenetics [Clin Epigenetics] 2023 Sep 11; Vol. 15 (1), pp. 148. Date of Electronic Publication: 2023 Sep 11.

Validation and characterisation of a DNA methylation alcohol biomarker across the life course.

Autor: Yousefi PD; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK. paul.yousefi@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. paul.yousefi@bristol.ac.uk., Richmond R; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Langdon R; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Ness A; National Institute of Health Bristol Biomedical Research Centre, University of Bristol, Bristol, UK.; Bristol Dental School, University of Bristol, Bristol, UK., Liu C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Levy D; The Framingham Heart Study, Framingham, MA, USA.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Bethesda, MD, USA., Relton C; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Suderman M; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Zuccolo L; MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Publikováno v: Clinical epigenetics [Clin Epigenetics] 2019 Nov 27; Vol. 11 (1), pp. 163. Date of Electronic Publication: 2019 Nov 27.