Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yousef Hajikarimian"'
Autor:
David Clifford, John R. Williams, Terry V. Silk, Christopher P. Ashcroft, Nicholas Murray Thomson, Yousef Hajikarimian, Andrew Derrick, Keith Slucock, Stephen Challenger
Publikováno v:
Organic Process Research & Development. 9:663-669
The development and scale-up of a potential manufacturing route to the endothelin antagonists UK-350,926 1 and UK-349,862 2 are described. A key synthetic challenge in designing an efficient route ...
Autor:
Nicholas Murray Thomson, Stephen Challenger, Yousef Hajikarimian, Christopher P. Ashcroft, Andrew Derrick
Publikováno v:
Process Chemistry in the Pharmaceutical Industry, Volume 2: Challenges in an Ever Changing Climate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c2f27f5f209797a2eaf5a8372451bc7
https://doi.org/10.1201/9781420008357.ch10
https://doi.org/10.1201/9781420008357.ch10
Autor:
Robin Bannister, Lewis Norman John, Amin Shamji, Peter M. Ayrey, Brian M. Adger, Michael Anthony Forth, C. O'farrell, Nicholas Owens, Yousef Hajikarimian
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2791
A synthesis of methyl 3-(2-methoxy-4-pyridyl)propionate (2), a key intermediate in the synthesis of the potent long-acting histamine H2-receptor antagonist SK&F 93574 (1), is described. The key step in the synthesis of compound (1) involves alkylatio