Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Autor: Alexander Teumer, Layal Chaker, Stefan Groeneweg, Yong Li, Celia Di Munno, Caterina Barbieri, Ulla T. Schultheiss, Michela Traglia, Tarunveer S. Ahluwalia, Masato Akiyama, Emil Vincent R. Appel, Dan E. Arking, Alice Arnold, Arne Astrup, Marian Beekman, John P. Beilby, Sofie Bekaert, Eric Boerwinkle, Suzanne J. Brown, Marc De Buyzere, Purdey J. Campbell, Graziano Ceresini, Charlotte Cerqueira, Francesco Cucca, Ian J. Deary, Joris Deelen, Kai-Uwe Eckardt, Arif B. Ekici, Johan G. Eriksson, Luigi Ferrrucci, Tom Fiers, Edoardo Fiorillo, Ian Ford, Caroline S. Fox, Christian Fuchsberger, Tessel E. Galesloot, Christian Gieger, Martin Gögele, Alessandro De Grandi, Niels Grarup, Karin Halina Greiser, Kadri Haljas, Torben Hansen, Sarah E. Harris, Diana van Heemst, Martin den Heijer, Andrew A. Hicks, Wouter den Hollander, Georg Homuth, Jennie Hui, M. Arfan Ikram, Till Ittermann, Richard A. Jensen, Jiaojiao Jing, J. Wouter Jukema, Eero Kajantie, Yoichiro Kamatani, Elisa Kasbohm, Jean-Marc Kaufman, Lambertus A. Kiemeney, Margreet Kloppenburg, Florian Kronenberg, Michiaki Kubo, Jari Lahti, Bruno Lapauw, Shuo Li, David C. M. Liewald, Lifelines Cohort Study, Ee Mun Lim, Allan Linneberg, Michela Marina, Deborah Mascalzoni, Koichi Matsuda, Daniel Medenwald, Christa Meisinger, Ingrid Meulenbelt, Tim De Meyer, Henriette E. Meyer zu Schwabedissen, Rafael Mikolajczyk, Matthijs Moed, Romana T. Netea-Maier, Ilja M. Nolte, Yukinori Okada, Mauro Pala, Cristian Pattaro, Oluf Pedersen, Astrid Petersmann, Eleonora Porcu, Iris Postmus, Peter P. Pramstaller, Bruce M. Psaty, Yolande F. M. Ramos, Rajesh Rawal, Paul Redmond, J. Brent Richards, Ernst R. Rietzschel, Fernando Rivadeneira, Greet Roef, Jerome I. Rotter, Cinzia F. Sala, David Schlessinger, Elizabeth Selvin, P. Eline Slagboom, Nicole Soranzo, Thorkild I. A. Sørensen, Timothy D. Spector, John M. Starr, David J. Stott, Youri Taes, Daniel Taliun, Toshiko Tanaka, Betina Thuesen, Daniel Tiller, Daniela Toniolo, Andre G. Uitterlinden, W. Edward Visser, John P. Walsh, Scott G. Wilson, Bruce H. R. Wolffenbuttel, Qiong Yang, Hou-Feng Zheng, Anne Cappola, Robin P. Peeters, Silvia Naitza, Henry Völzke, Serena Sanna, Anna Köttgen, Theo J. Visser, Marco Medici

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

Thyroid dysfunction is a common public health problem and associated with cardiovascular co-morbidities. Here, the authors carry out genome-wide meta-analysis for thyroid hormone (TH) levels, hyper- and hypothyroidism and identify SLC17A4 as a TH tra

Externí odkaz: https://doaj.org/article/34ab5dc1d5c54e85877b61677f6ec6a8

Relationship Between Time in Range, Glycemic Variability, HbA1c, and Complications in Adults With Type 1 Diabetes Mellitus

Autor: Chantal Mathieu, Régis Radermecker, Pieter Gillard, Bart Keymeulen, Michiel Van Elsen, Sara Charleer, Eveline Dirinck, Chris Vercammen, Anass El Malahi, Laurent Crenier, Youri Taes, Kristien J. Ledeganck, Frank Nobels, Christophe De Block

Publikováno v: The journal of clinical endocrinology and metabolism

Purpose Real-time continuous glucose monitoring (RT-CGM) provides information on glycemic variability (GV), time in range (TIR), and guidance to avoid hypoglycemia, thereby complimenting HbA1c for diabetes management. We investigated whether GV and T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be44c3d8d90a8c54c999d2b3417e6454
https://doi.org/10.1210/clinem/dgab688

Growth, sexual and bone development in a boy with bilateral anorchia under testosterone treatment guided by the development of his monozygotic twin

Autor: Sara Vandewalle, Youri Taes, Jean-Marc Kaufman, Margarita Craen, Guy T'Sjoen, Eva Van Caenegem

Publikováno v: Journal of Pediatric Endocrinology and Metabolism. 31:361-367

Background:Sex steroids are essential for sexual maturation, linear growth and bone development. However, there is no consensus on the optimal timing, dosage and dosage interval of testosterone therapy to induce pubertal development and achieve a nor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d1154a177ef4d9dba42d8a91ec68b21
https://doi.org/10.1515/jpem-2017-0126

An unusual case of pubertas tarda: IGSF-1 deficiency syndrome

Autor: I Matthys, Youri Taes, B Callewaert, Schepper J De

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b0f401e903e97cffc4385da564e2bcf
https://doi.org/10.1530/endoabs.64.034

Effect of continuous glucose monitoring on glycemic control, acute admissions, and quality of life : a real-world study

Autor: Pieter Gillard, Régis Radermecker, Rescue Trial Investigators, Sara Charleer, Steffen Fieuws, Chris Vercammen, Michel P. Hermans, Laurent Crenier, Frank Nobels, Bart Keymeulen, Youri Taes, Chantal Mathieu, Christophe De Block, Guy T'Sjoen

Publikováno v: The journal of clinical endocrinology and metabolism
The Journal of Clinical Endocrinology & Metabolism, Vol. 103, no. 3, p. 1224-1232 (2018)

CONTEXT: Randomized controlled trials evaluating real-time continuous glucose monitoring (RT-CGM) patients with type 1 diabetes (T1D) show improved glycemic control, but limited data are available on real-world use. OBJECTIVE: To assess impact of RT-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6731b6b3cfbc128a66bd4c1035647e2
https://hdl.handle.net/10067/1500820151162165141