Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Youqiong, Ye"'
Autor:
Hongdong Wang, Yanhua Du, Shanshan Huang, Xitai Sun, Youqiong Ye, Haixiang Sun, Xuehui Chu, Xiaodong Shan, Yue Yuan, Lei Shen, Yan Bi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Adipose progenitor cells (APCs) are heterogeneous stromal cells and help to maintain metabolic homeostasis. However, the influence of obesity on human APC heterogeneity and the role of APC subpopulations on regulating glucose homeostasis rem
Externí odkaz:
https://doaj.org/article/0b8630e8f4974402a30fde7d88b36340
Autor:
Zhenzhen Xun, Huanran Zhou, Mingyi Shen, Yao Liu, Chengcao Sun, Yanhua Du, Zhou Jiang, Liuqing Yang, Qing Zhang, Chunru Lin, Qingsong Hu, Youqiong Ye, Leng Han
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Although hypoxia is known to be associated with immune resistance, the adaptability to hypoxia by different cell populations in the tumor microenvironment and the underlying mechanisms remain elusive. This knowledge gap has hindered the deve
Externí odkaz:
https://doaj.org/article/23fd95d98cd0466eac089c2f0d848fcc
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101740- (2024)
Spatially resolved multi-omics revolutionizes cancer therapy by decoding the cellular and molecular heterogeneity of the tumor microenvironment through spatial coordinates. This commentary discusses the roles of spatial multi-omics in identifying pre
Externí odkaz:
https://doaj.org/article/58afd021992c4e9eb6282c081cd3755f
Autor:
Song Li, Xinxing Ouyang, Hongxiang Sun, Jingsi Jin, Yao Chen, Liang Li, Qijun Wang, Yingzhong He, Jiwen Wang, Tongxin Chen, Qing Zhong, Yinming Liang, Philippe Pierre, Qiang Zou, Youqiong Ye, Bing Su
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Peripheral CD8+ T cell number is tightly controlled but the precise molecular mechanism regulating this process is still not fully understood. In this study, we found that epilepsy patients with loss of function mutation of DEPDC5 had reduce
Externí odkaz:
https://doaj.org/article/824b50abd9694c4e8e1778931ed140ef
Autor:
Haidi Huang, Yu Jiang, Jiangying Liu, Dan Luo, Jianghong Yuan, Rongzi Mu, Xiang Yu, Donglei Sun, Jihong Lin, Qiyue Chen, Xinjing Li, Ming Jiang, Jianming Xu, Bo Chu, Chengqian Yin, Lei Zhang, Youqiong Ye, Bo Cao, Qiong Wang, Yongchun Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Basal progenitor cells are crucial for maintaining foregut (the esophagus and forestomach) homeostasis. When their function is dysregulated, it can promote inflammation and tumorigenesis. However, the mechanisms underlying these processes re
Externí odkaz:
https://doaj.org/article/aebb3e94c68b4ce7a03b50aeac0c0035
Autor:
Shaojian Lin, Yuting Dai, Changxi Han, Tianyi Han, Linfeng Zhao, Renyan Wu, Jianyue Liu, Bo Zhang, Ning Huang, Yanting Liu, Shujing Lai, Jintong Shi, Yu Wang, Meiqing Lou, Jing Xie, Yijun Cheng, Hao Tang, Hong Yao, Hai Fang, Yan Zhang, Xuefeng Wu, Lei Shen, Youqiong Ye, Li Xue, Zhe Bao Wu
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-22 (2024)
Abstract Background Pituitary neuroendocrine tumors (PitNETs) are common gland neoplasms demonstrating distinctive transcription factors. Although the role of immune cells in PitNETs has been widely recognized, the precise immunological environment a
Externí odkaz:
https://doaj.org/article/52c6217dd28941fa83eebbb4d1b0a954
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Pyroptosis, mediated by gasdermins with the release of multiple inflammatory cytokines, has emerged as playing an important role in targeted therapy and immunotherapy due to its effectiveness at inhibiting tumor growth. Melanoma i
Externí odkaz:
https://doaj.org/article/e464ff477fef4245bc95718860abcdd0
Autor:
Yu Dong, Qian Gao, Yong Chen, Zhao Zhang, Yanhua Du, Yuan Liu, Guangxiong Zhang, Shengli Li, Gaoyang Wang, Xiang Chen, Hong Liu, Leng Han, Youqiong Ye
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Circular RNAs (circRNAs) play important roles in the regulation of cancer. However, the clinical implications and regulatory networks of circRNAs in cancer patients receiving immune checkpoint blockades (ICB) have not been fully elucidated.
Externí odkaz:
https://doaj.org/article/072cf275c2e5448fa16d892691f8b1c0
Autor:
Muqing Cao, Xiaoxiao Zou, Chaoyi Li, Zaisheng Lin, Ni Wang, Zhongju Zou, Youqiong Ye, Joachim Seemann, Beth Levine, Zaiming Tang, Qing Zhong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Dysfunction of cell cycle control and defects of primary ciliogenesis are two features of many cancers. Whether these events are interconnected and the driving mechanism coordinating them remains elusive. Here, we identify an actin filament
Externí odkaz:
https://doaj.org/article/5a4e7b718e5d4006ac84d208fd7b4f6c
Autor:
Muqing Cao, Xiaoxiao Zou, Chaoyi Li, Zaisheng Lin, Ni Wang, Zhongju Zou, Youqiong Ye, Joachim Seemann, Beth Levine, Zaiming Tang, Qing Zhong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/4b6f113d046c4d62bdde598209ce488f