Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Youpei Lin"'
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 3, Pp 181-195 (2023)
Advances in antibody engineering have led to the generation of more innovative antibody drugs, such as bispecific antibodies (bsAbs). Following the success associated with blinatumomab, bsAbs have attracted enormous interest in the field of cancer im
Externí odkaz:
https://doaj.org/article/a0d19bf45b04422996cf72d5f49e7f31
Autor:
Yingyu Xu, Xin Xu, Xiaojian Ni, Jiaomeng Pan, MaoPei Chen, Youpei Lin, Zhiying Zhao, Lan Zhang, Ningling Ge, Guohe Song, Juan Zhang
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13269- (2023)
Cancer/testis antigens (CTAs) are reproductive tissue-restricted genes, frequently ectopic expressed in tumors. CTA genes associate with a poor prognosis in some solid tumors, due to their potential roles in the tumorigenesis and progression. However
Externí odkaz:
https://doaj.org/article/d39f1e1ef035452ea6f50f10c3abfd7a
Autor:
Guohe Song, Yang Shi, Lu Meng, Jiaqiang Ma, Siyuan Huang, Juan Zhang, Yingcheng Wu, Jiaxin Li, Youpei Lin, Shuaixi Yang, Dongning Rao, Yifei Cheng, Jian Lin, Shuyi Ji, Yuming Liu, Shan Jiang, Xiaoliang Wang, Shu Zhang, Aiwu Ke, Xiaoying Wang, Ya Cao, Yuan Ji, Jian Zhou, Jia Fan, Xiaoming Zhang, Ruibin Xi, Qiang Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The molecular classification and tumour microenvironment in intrahepatic cholangiocarcinoma (iCCA) need further characterisation. Here, the authors perform single cell RNA-sequencing from 14 pairs of iCCA tumours and non-tumour liver tissues and prop
Externí odkaz:
https://doaj.org/article/d1872e649e1344dba5a7cc26ee3c1275
Autor:
Yuming Liu, Jinmai Zhang, Zhuo Wang, Jiaqiang Ma, Ke Wang, Dongning Rao, Mao Zhang, Youpei Lin, Yingcheng Wu, Zijian Yang, Liangqing Dong, Zhenbin Ding, Xiaoming Zhang, Jia Fan, Yongyong Shi, Qiang Gao
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104921- (2022)
Summary: The molecular landscape and pathogenesis of focal nodular hyperplasia (FNH) have yet to be elucidated. We performed multi-omics approaches on FNH and paired normal liver tissues from 22 patients, followed by multi-level bioinformatic analyse
Externí odkaz:
https://doaj.org/article/b4ceefc482bb40e7ad7060b499f42b7e
Autor:
Yin Li, Youpei Lin, Ling Aye, Liangqing Dong, Chenhao Zhang, Fanghua Chen, Yinkun Liu, Jia Fan, Qiang Gao, Haojie Lu, Chunlai Lu, Shu Zhang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/22906dbae89c4620b8e05365fbbdf144
Autor:
Guohe Song, Yang Shi, Meiying Zhang, Shyamal Goswami, Saifullah Afridi, Lu Meng, Jiaqiang Ma, Yi Chen, Youpei Lin, Juan Zhang, Yuming Liu, Zijie Jin, Shuaixi Yang, Dongning Rao, Shu Zhang, Aiwu Ke, Xiaoying Wang, Ya Cao, Jian Zhou, Jia Fan, Xiaoming Zhang, Ruibin Xi, Qiang Gao
Publikováno v:
Cell Discovery, Vol 6, Iss 1, Pp 1-15 (2020)
Abstract Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular carcinoma (HCC) still remains limited. To assess the plasticity and phenotypes of immune
Externí odkaz:
https://doaj.org/article/c5a666494abc4fdc99a5041b4b14afe1
Autor:
Hui Huang, Youpei Lin, Wenrui Ma, Jiannan Liu, Jing Han, Xiaoyi Hu, Meilin Tang, Shiqiang Yan, Mieradilijiang Abudupataer, Chenping Zhang, Qiang Gao, Weijia Zhang
Publikováno v:
eLife, Vol 10 (2021)
To assure complete tumor removal, frozen section analysis is the most common procedure for intraoperative pathological assessment of resected tumor margins. However, during one operation, multiple biopsies may be sent for examination, but only few of
Externí odkaz:
https://doaj.org/article/726d1170cc6b4532a6f30685452d07c1
Autor:
Guohe Song, Yang Shi, Lu Meng, Jiaqiang Ma, Siyuan Huang, Juan Zhang, Yingcheng Wu, Jiaxin Li, Youpei Lin, Shuaixi Yang, Dongning Rao, Yifei Cheng, Jian Lin, Shuyi Ji, Yuming Liu, Shan Jiang, Xiaoliang Wang, Shu Zhang, Aiwu Ke, Xiaoying Wang, Ya Cao, Yuan Ji, Jian Zhou, Jia Fan, Xiaoming Zhang, Ruibin Xi, Qiang Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/d0f908c656ea4fb5966c094e6f65bf0c
Autor:
Fanghua Chen, Ling Aye, Lei Yu, Longzi Liu, Yuming Liu, Youpei Lin, Dongmei Gao, Qiang Gao, Shu Zhang
Publikováno v:
Carcinogenesis. 44:232-241
Protein tyrosine phosphatases (PTPs) are involved in malignant transformation and metastasis. According to one of our previous studies, Slingshot homolog 1 (SSH1), a member of PTPs, is significantly associated with the survival of intrahepatic cholan
Autor:
Youpei Lin, Lihua Peng, Liangqing Dong, Dongbing Liu, Jiaqiang Ma, Jian Lin, Xiaofang Chen, Penghui Lin, Guohe Song, Mao Zhang, Yuming Liu, Junhua Rao, Chen Wei, Ye Lu, Shu Zhang, Guangyu Ding, Zhenyu Peng, Haorong Lu, Xiaoying Wang, Jian Zhou, Jia Fan, Kui Wu, Qiang Gao
Publikováno v:
Cancer Discovery. 12:2350-2371
Intrahepatic cholangiocarcinoma (iCCA) exhibits extensive intratumoral heterogeneity and an extremely high mortality rate. Here, we performed whole-exome sequencing, RNA sequencing, T-cell receptor (TCR) sequencing, and multiplexed immunofluorescence