Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Younseo Oh"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
Abstract While their function, as immune checkpoint molecules, is well known, B7-family proteins also function as regulatory molecules in bone remodeling. B7–H3 is a receptor ligand of the B7 family that functions primarily as a negative immune che
Externí odkaz:
https://doaj.org/article/2dd15614197f44f1bf4d5570f6f8e97a
Autor:
Se Hwan Mun, Seyeon Bae, Steven Zeng, Brian Oh, Carmen Chai, Matthew Jundong Kim, Haemin Kim, George Kalliolias, Chitra Lekha Dahia, Younseo Oh, Tae-Hwan Kim, Jong Dae Ji, Kyung-Hyun Park-Min
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA). However, the role of M-CSF
Externí odkaz:
https://doaj.org/article/3a5bddf68ff148bea59fec14bf85d5e3
Publikováno v:
Cells, Vol 10, Iss 12, p 3498 (2021)
Aryl-hydrocarbon receptor (AhR) is a ligand-activated transcription factor and regulates differentiation and function of various immune cells such as dendritic cells, Th17, and regulatory T cells. In recent studies, it was reported that AhR is involv
Externí odkaz:
https://doaj.org/article/97d023f881da453388a36f1c01e9cd49
Autor:
Chanhyeok Jeon, Yurin Jang, Seung Hoon Lee, Subin Weon, Hyosun Park, Suein Lee, Younseo Oh, Sung Hoon Choi, Sung Eun Wang, Tae-Hwan Kim, Il-Hoon Sung, Sungsin Jo
Publikováno v:
International Immunopharmacology. 118:110132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d28853d4ca2d43e800343036979c0067
https://doi.org/10.1016/j.intimp.2023.110132
https://doi.org/10.1016/j.intimp.2023.110132
Autor:
Young Lim Lee, Seong Su Kim, Chul-Su Yang, Jae Hyuk Yang, Younseo Oh, Jee Young Chung, Tae-Hwan Kim, Yoonsung Song, Yong-Hee Kim, Kiseok Jang, Subin Yoon, Sungsin Jo
Publikováno v:
Journal of Controlled Release. 330:1300-1312
Excessive tumor necrosis factor-α (TNF-α) is associated with the pathogenesis of rheumatoid arthritis (RA). Approximately 90% of patients with RA, who have inadequate response to methotrexate, follow anti-TNF-α therapy as the first-line immuno-tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c069ad9f9d1c48b39c3724a2551cf2b8
https://doi.org/10.1016/j.jconrel.2020.11.041
https://doi.org/10.1016/j.jconrel.2020.11.041
Autor:
Jong Dae Ji, Steven Zeng, Carmen Chai, Se Hwan Mun, Matthew Jundong Kim, Haemin Kim, Tae-Hwan Kim, Brian Oh, Kyung-Hyun Park-Min, Younseo Oh, Chitra Lekha Dahia, Seyeon Bae, George D. Kalliolias
Publikováno v:
Bone Research
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA). However, the role of M-CSF in arthri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a96f68459eda9753949f28a8a5dfef
http://europepmc.org/articles/PMC8528869
http://europepmc.org/articles/PMC8528869
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
While their function, as immune checkpoint molecules, is well known, B7-family proteins also function as regulatory molecules in bone remodeling. B7–H3 is a receptor ligand of the B7 family that functions primarily as a negative immune checkpoint.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300ee9f2b670a4a6007635dc19fd2344
http://europepmc.org/articles/PMC8528854
http://europepmc.org/articles/PMC8528854
Autor:
Il Hoon Sung, Sungsin Jo, Young Lim Lee, Joong-Soo Han, Subin Yoon, Jaehyun Lee, Jinil Han, Ye Soo Park, Younseo Oh, Tae-Hwan Kim, Yun Young Lee
Publikováno v:
BMB Reports
Receptor activator of nuclear factor kappa B ligand (RANKL) expression in osteoblasts is regulated by 1,25-dihydroxyvitamin D3 (1,25D3). CCAAT/enhancer-binding protein beta (C/EBPβ) has been proposed to function as a transcription factor and upregul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4181c7b67c5b4d0eb508de12664ebccc
https://doi.org/10.5483/bmbrep.2019.52.6.166
https://doi.org/10.5483/bmbrep.2019.52.6.166
Publikováno v:
Immunology Letters. 206:33-40
TGF-β1 is highly expressed in the synovial tissue of patients with rheumatoid arthritis and is known as a cytokine that plays an important role in tissue repair and immune cell regulation. However, the role of TGF-β1 is still unclear in osteoclasto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0cde0ed74556e71aabd711aa3061c3
https://doi.org/10.1016/j.imlet.2018.12.003
https://doi.org/10.1016/j.imlet.2018.12.003
Autor:
Young Lim Lee, Sung Hoon Choi, Tae-Hwan Kim, So Yeon Kim, Jae Hyuk Yang, Bora Nam, Hyosun Park, Sungsin Jo, Subin Weon, Younseo Oh, Jinsung Park
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9771, p 9771 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
Transforming growth factor &beta
1 (TGF&beta
1) is a major mediator in the modulation of osteoblast differentiation. However, the underlying molecular mechanism is still not fully understood. Here, we show that TGF&beta
1 has a dual st
1 (TGF&beta
1) is a major mediator in the modulation of osteoblast differentiation. However, the underlying molecular mechanism is still not fully understood. Here, we show that TGF&beta
1 has a dual st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4154e58d42588d7296b34e0fb5ef7249
https://www.mdpi.com/1422-0067/21/24/9771
https://www.mdpi.com/1422-0067/21/24/9771