Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Younkin, Curtis"'
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases
Autor:
Allen, Mariet, Wang, Xue, Burgess, Jeremy D., Watzlawik, Jens, Serie, Daniel J., Younkin, Curtis S., Nguyen, Thuy, Malphrus, Kimberly G., Lincoln, Sarah, Carrasquillo, Minerva M., Ho, Charlotte, Chakrabarty, Paramita, Strickland, Samantha, Murray, Melissa E., Swarup, Vivek, Geschwind, Daniel H., Seyfried, Nicholas T., Dammer, Eric B., Lah, James J., Levey, Allan I., Golde, Todd E., Funk, Cory, Li, Hongdong, Price, Nathan D., Petersen, Ronald C., Graff-Radford, Neill R., Younkin, Steven G., Dickson, Dennis W., Crook, Julia R., Asmann, Yan W., Ertekin-Taner, Nilüfer
Publikováno v:
In Alzheimer's & Dementia: The Journal of the Alzheimer's Association March 2018 14(3):352-366
Autor:
Carrasquillo, Minerva M., Allen, Mariet, Burgess, Jeremy D., Wang, Xue, Strickland, Samantha L., Aryal, Shivani, Siuda, Joanna, Kachadoorian, Michaela L., Medway, Christopher, Younkin, Curtis S., Nair, Asha, Wang, Chen, Chanana, Pritha, Serie, Daniel, Nguyen, Thuy, Lincoln, Sarah, Malphrus, Kimberly G., Morgan, Kevin, Golde, Todd E., Price, Nathan D., White, Charles C., De Jager, Philip L., Bennett, David A., Asmann, Yan W., Crook, Julia E., Petersen, Ronald C., Graff-Radford, Neill R., Dickson, Dennis W., Younkin, Steven G., Ertekin-Taner, Nilüfer
Publikováno v:
In Alzheimer's & Dementia: The Journal of the Alzheimer's Association June 2017 13(6):663-673
Autor:
Allen Mariet, Zou Fanggeng, Chai High, Younkin Curtis S, Miles Richard, Nair Asha A, Crook Julia E, Pankratz V, Carrasquillo Minerva M, Rowley Christopher N, Nguyen Thuy, Ma Li, Malphrus Kimberly G, Bisceglio Gina, Ortolaza Alexandra I, Palusak Ryan, Middha Sumit, Maharjan Sooraj, Georgescu Constantin, Schultz Debra, Rakhshan Fariborz, Kolbert Christopher P, Jen Jin, Sando Sigrid B, Aasly Jan O, Barcikowska Maria, Uitti Ryan J, Wszolek Zbigniew K, Ross Owen A, Petersen Ronald C, Graff-Radford Neill R, Dickson Dennis W, Younkin Steven G, Ertekin-Taner Nilüfer
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 13 (2012)
Abstract Background Glutathione S-transferase omega-1 and 2 genes (GSTO1, GSTO2), residing within an Alzheimer and Parkinson disease (AD and PD) linkage region, have diverse functions including mitigation of oxidative stress and may underlie the path
Externí odkaz:
https://doaj.org/article/9cb1ecd93ab640ba96fd4aff80cfec02
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Carrasquillo, Minerva M., Zou, Fanggeng, Pankratz, V. Shane, Wilcox, Samantha L., Ma, Li, Walker, Louise P., Younkin, Samuel G., Younkin, Curtis S., Younkin, Linda H., Bisceglio, Gina D., Ertekin-Taner, Nilufer, Crook, Julia E., Dickson, Dennis W., Peterson, Rnald C., Graff-Radford, Neill R., Younkin, Steven G.
Publikováno v:
弘前医学. 61:S125-S134
By analyzing late onset Alzheimer’s disease (LOAD) in a genome wide association study of 3 American Caucasian series and evaluating the 25 SNPs with most significant allelic association in 4 additional series, we identifi ed a SNP (rs5984894
Autor:
Kouri, Naomi, Ross, Owen A, Dombroski, Beth, Younkin, Curtis S, Serie, Daniel J, Soto-Ortolaza, Alexandra, Baker, Matthew, Finch, Ni Cole A, Yoon, Hyejin, Kim, Jungsu, Fujioka, Shinsuke, McLean, Catriona A, Ghetti, Bernardino, Spina, Salvatore, Cantwell, Laura B, Farlow, Martin R, Grafman, Jordan, Huey, Edward D, Ryung Han, Mi, Beecher, Sherry, Geller, Evan T, Kretzschmar, Hans A, Roeber, Sigrun, Gearing, Marla, Juncos, Jorge L, Vonsattel, Jean Paul G, Van Deerlin, Vivianna M, Grossman, Murray, Hurtig, Howard I, Gross, Rachel G, Arnold, Steven E, Trojanowski, John Q, Lee, Virginia M, Wenning, Gregor K, White, Charles L, Höglinger, Günter U, Müller, Ulrich, Devlin, Bernie, Golbe, Lawrence I, Crook, Julia, Parisi, Joseph E, Boeve, Bradley F, Josephs, Keith A, Wszolek, Zbigniew K, Uitti, Ryan J, Graff-Radford, Neill R, Litvan, Irene, Younkin, Steven G, Wang, Li-San, Ertekin-Taner, Nilüfer, Rademakers, Rosa, Hakonarsen, Hakon, Schellenberg, Gerard D, Dickson, Dennis W
Publikováno v:
Nature communications, vol 6, iss 1
Corticobasal degeneration (CBD) is a neurodegenerative disorder affecting movement and cognition, definitively diagnosed only at autopsy. Here, we conduct a genome-wide association study (GWAS) in CBD cases (n=152) and 3,311 controls, and 67 CBD case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::000a7818eda74c3b5afac83823c14a44
https://escholarship.org/uc/item/10b9b78t
https://escholarship.org/uc/item/10b9b78t
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
Autor:
Srivastava, Gyan, Lunnon, Katie, Burgess, Jeremy, Yu, Lei, Ernst, Jason, McCabe, Cristin, Tang, Anna, Raj, Towfique, Replogle, Joseph, Brodeur, Wendy, Gabriel, Stacey, Younkin, Curtis, Zou, Fanggeng, Szyf, Moshe, Meissner, Alexander, Ertekin-Taner, Nilufer, Kellis, Manolis, Mill, Jonathan, De Jager, Philip L., Schalkwyk, Leonard C., Eaton, Matthew Lucas, Eaton, Matthew L., Keenan, Brendan T., Chai, High S., Younkin, Steven G., Epstein, Charles B., Schneider, Julie A., Bernstein, Bradley E., Chibnik, Lori B., Bennett, David A.
Publikováno v:
Nature neuroscience, vol 17, iss 9
Nature neuroscience
PMC
Nature neuroscience
PMC
We used a collection of 708 prospectively collected autopsied brains to assess the methylation state of the brain's DNA in relation to Alzheimer's disease (AD). We found that the level of methylation at 71 of the 415,848 interrogated CpGs was signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a974837cae6e59fe63347d554da5f01
https://escholarship.org/uc/item/2ht9t8pf
https://escholarship.org/uc/item/2ht9t8pf
Autor:
Reddy, Joseph S., Allen, Mariet, Wang, Xue, Biernacka, Joanna M., Gregory, Jenkins D., Toral, Shastri M., McDonnell, Shannon K., Sarangi, Vivekananda, Sinnwell, Jason P., Asmann, Yan W., Carrasquillo, Minerva M., Pottier, Cyril P., Ren, Yingxue, Younkin, Curtis S., Rademakers, Rosa, Ross, Owen A., Ertekin-Taner, Nilufer, Younkin, Steven G.
Publikováno v:
In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2018 14(7) Supplement:P1025-P1026