Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Younis Baqi"'
Autor:
Ahmed Mutanabbi Abdula, Ghosoun Lafta Mohsen, Bilal H. Jasim, Majid S. Jabir, Abduljabbar I.R. Rushdi, Younis Baqi
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32257- (2024)
New 3-furan-1-thiophene-based chalcones were synthesized, characterized and pharmacologically evaluated as antibacterial and anticancer agents against two bacterial species; Gram-positive (Streptococcus pyogenes) and Gram-negative (Pseudomonas aerugi
Externí odkaz:
https://doaj.org/article/2e9d77a83ed349f0aba427498c82aade
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 21 (2023)
The present work focuses on the synthesis and preliminary structure activity relationships (SARs) of furan-derived chalcones and their corresponding ∆2-pyrazoline derivatives as antimicrobial agents. Eight novel chalcone derivatives and eight ∆2-
Externí odkaz:
https://doaj.org/article/b1c856c91d77442aa17e749d20bad5ba
Publikováno v:
Al-Mustansiriyah Journal of Science, Vol 32, Iss 4, Pp 26-33 (2021)
A new series of 2-substituted-1H-benzimidazol as potentially antimicrobial agents were designed, synthesized and characterized by IR, 1H-NMR and Mass spectra. The synthesized compounds were in vitro screened against Escherichia coli, Klebsiella spp.
Externí odkaz:
https://doaj.org/article/28a7acd3d68b4d5bbc84f65f5975dc73
Autor:
Fatma Al-Rubaiai, Zakiya Zahran Al-Shariqi, Khalsa S. Al-Shabibi, John Husband, Asmaa M. Al-Hattali, Marcia Goettert, Stefan Laufer, Younis Baqi, Syed Imran Hassan, Majekodunmi O. Fatope
Publikováno v:
Molecules, Vol 28, Iss 16, p 6077 (2023)
Maytenus dhofarensis Sebsebe (Celestraceae) is a naturally growing shrub in Oman. It is not a reputed medicinal plant in Oman, but it is regionally endemic and causes shivering attacks on goats that graze on it. The chemical investigation of the hexa
Externí odkaz:
https://doaj.org/article/a6184f3a3db9437cba04066cbd899d4f
Autor:
Reiner Schneider, Patrick Leven, Tim Glowka, Ivan Kuzmanov, Mariola Lysson, Bianca Schneiker, Anna Miesen, Younis Baqi, Claudia Spanier, Iveta Grants, Elvio Mazzotta, Egina Villalobos‐Hernandez, Jörg C Kalff, Christa E Müller, Fedias L Christofi, Sven Wehner
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 1, Pp 1-20 (2020)
Abstract Enteric glial cells (EGC) modulate motility, maintain gut homeostasis, and contribute to neuroinflammation in intestinal diseases and motility disorders. Damage induces a reactive glial phenotype known as “gliosis”, but the molecular ide
Externí odkaz:
https://doaj.org/article/f5469403716a46148ae5ebeaac3b0ffb
Autor:
Wenjin Li, Joren Guillaume, Younis Baqi, Isabell Wachsmann, Volkmar Gieselmann, Serge Van Calenbergh, Christa E. Müller
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1503-1512 (2020)
Metachromatic leukodystrophy (MLD) is a rare genetic disease characterised by a dysfunction of the enzyme arylsulphatase A leading to the lysosomal accumulation of cerebroside sulphate (sulphatide) causing subsequent demyelination in patients. The en
Externí odkaz:
https://doaj.org/article/583b2f06989a4d3d8e2f03ed4b6cde5e
Autor:
Younis Baqi, Mahmoud Rashed, Laura Schäkel, Enas M. Malik, Julie Pelletier, Jean Sévigny, Amelie Fiene, Christa E. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Ectonucleoside triphosphate diphosphohydrolases (NTPDases) catalyze the hydrolysis of nucleoside tri- and di-phosphates to mono-phosphates. The products are subsequently hydrolyzed by ecto-5′-nucleotidase (ecto-5′-NT) to nucleosides. NTPDase inhi
Externí odkaz:
https://doaj.org/article/e7d069e48d514c518acb6445ea293fe9
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 121, Iss , Pp 109522- (2020)
Date palm fruit (Phoenix dactylifera L.) is an endemic functional food, with great nutritional and economic importance due to its phytochemical compositions. The microenvironment of pancreatic cancer consists of cellular and acellular components, inc
Externí odkaz:
https://doaj.org/article/9d978fbf08204119af344c50d9514baa
Autor:
Emilie Faivre, Joana E. Coelho, Katja Zornbach, Enas Malik, Younis Baqi, Marion Schneider, Lucrezia Cellai, Kevin Carvalho, Shéhérazade Sebda, Martin Figeac, Sabiha Eddarkaoui, Raphaëlle Caillierez, Yijuang Chern, Michael Heneka, Nicolas Sergeant, Christa E. Müller, Annett Halle, Luc Buée, Luisa V. Lopes, David Blum
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Consumption of caffeine, a non-selective adenosine A2A receptor (A2AR) antagonist, reduces the risk of developing Alzheimer’s disease (AD) and mitigates both amyloid and Tau lesions in transgenic mouse models of the disease. While short-term treatm
Externí odkaz:
https://doaj.org/article/28a678928c254d56b36a2ddfc3b2ac6c
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 2326-2333 (2015)
Anthraquinone (AQ) derivatives play a prominent role in medicine and also in textile industry. Bromaminic acid (1-amino-4-bromoanthraquinone-2-sulfonic acid) is an important precursor for obtaining dyes as well as biologically active compounds throug
Externí odkaz:
https://doaj.org/article/795a8938e0f243a5b141fc49b05e64a9